Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Catherine M. Drerup"'
Publikováno v:
STAR Protocols, Vol 3, Iss 4, Pp 101766- (2022)
Summary: In this protocol, we describe steps that utilize the optical clarity of the zebrafish larvae and the stereotyped motor neuron axon structure in the trunk to measure spontaneous or evoked motor neuron axon activity. This activity is detected
Externí odkaz:
https://doaj.org/article/46436a2e02374d13817c3a0321aeedda
Autor:
Dane Kawano, Katherine Pinter, Madison Chlebowski, Ronald S. Petralia, Ya-Xian Wang, Alex V. Nechiporuk, Catherine M. Drerup
Publikováno v:
iScience, Vol 25, Iss 10, Pp 105072- (2022)
Summary: In the axon terminal, microtubule stability is decreased relative to the axon shaft. The dynamic microtubule plus ends found in the axon terminal have many functions, including serving as a docking site for the Cytoplasmic dynein motor. Here
Externí odkaz:
https://doaj.org/article/b65a0b263d814dbb8ca317db429152c9
Autor:
Amrita Mandal, Catherine M. Drerup
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 13 (2019)
The complex and elaborate architecture of a neuron poses a great challenge to the cellular machinery which localizes proteins and organelles, such as mitochondria, to necessary locations. Proper mitochondrial localization in neurons is particularly i
Externí odkaz:
https://doaj.org/article/f10953438fff4c62b19a4bb5ebd72bcd
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 6 (2018)
Despite their importance for cellular viability, the actual life history and properties of mitochondria in neurons are still unclear. These organelles are distributed throughout the entirety of the neuron and serve many functions, including: energy p
Externí odkaz:
https://doaj.org/article/36dc3bc41a2544d4bfb732f3800a77f4
Publikováno v:
eLife, Vol 8 (2019)
The trafficking mechanisms and transcriptional targets downstream of long-range neurotrophic factor ligand/receptor signaling that promote axon growth are incompletely understood. Zebrafish carrying a null mutation in a neurotrophic factor receptor,
Externí odkaz:
https://doaj.org/article/53e5df06c6ce4567a21e501b970d0619
Publikováno v:
eLife, Vol 6 (2017)
Mitochondrial transport in axons is critical for neural circuit health and function. While several proteins have been found that modulate bidirectional mitochondrial motility, factors that regulate unidirectional mitochondrial transport have been har
Externí odkaz:
https://doaj.org/article/06bd23a1046a4def96486aa452e2a301
Autor:
Dane Kawano, Katherine Pinter, Madison Chlebowski, Ronald S. Petralia, Ya-Xian Wang, Alex V. Nechiporuk, Catherine M Drerup
SummaryAxon terminal structure is critical for neuronal function. This cellular compartment houses synaptic terminals and is a site of high metabolic and functional demand. Axon terminals are also the site of a change in microtubule structure within
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d82b63ae9f6d2d64c9434e270851b265
https://doi.org/10.1101/2022.07.12.499810
https://doi.org/10.1101/2022.07.12.499810
Publikováno v:
Hearing Research. 431:108740
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::301968814f9b9141bcdedc716cf7b74f
https://doi.org/10.1016/j.heares.2023.108740
https://doi.org/10.1016/j.heares.2023.108740
Autor:
Sehoon Won, Katie S. Kindt, Hiu-Tung C. Wong, Amrita Mandal, Natalie Mosqueda, Katherine Pinter, Catherine M. Drerup, Alisha Beirl, Richa Madan Lomash
Publikováno v:
The Journal of Neuroscience
In neurons, mitochondria are transported by molecular motors throughout the cell to form and maintain functional neural connections. These organelles have many critical functions in neurons and are of high interest as their dysfunction is associated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3408644567e007011c6628ffe12d05e4
https://doi.org/10.1523/jneurosci.1316-20.2020
https://doi.org/10.1523/jneurosci.1316-20.2020
Publikováno v:
Genetics
Active transport of organelles within axons is critical for neuronal health. Retrograde axonal transport, in particular, relays neurotrophic signals received by axon terminals to the nucleus and circulates new material among en passant synapses. A si
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2821833d3be07d9bcc8f382fad264b55
https://pubmed.ncbi.nlm.nih.gov/32788307
https://pubmed.ncbi.nlm.nih.gov/32788307