Zobrazeno 1 - 10 of 17 pro vyhledávání: '"Catherine M Conway"'
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Akademický článek
Morphometry Predicts Early GFR Change in Primary Proteinuric Glomerulopathies: A Longitudinal Cohort Study Using Generalized Estimating Equations.
Autor: Kevin V Lemley, Serena M Bagnasco, Cynthia C Nast, Laura Barisoni, Catherine M Conway, Stephen M Hewitt, Peter X K Song
Publikováno v: PLoS ONE, Vol 11, Iss 6, p e0157148 (2016)
OBJECTIVE:Most predictive models of kidney disease progression have not incorporated structural data. If structural variables have been used in models, they have generally been only semi-quantitative. METHODS:We examined the predictive utility of qua
Externí odkaz: https://doaj.org/article/5a0226df1c314616a847c2674b2b826b
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4
The TRAIL receptor agonist drozitumab targets basal B triple-negative breast cancer cells that express vimentin and Axl
Autor: Sandra M. Swain, Ciara C. O’Sullivan, Donna Voeller, Laleh Amiri-Kordestani, Jennifer L. Dine, Stephen M. Hewitt, Anand S. Merchant, Catherine M. Conway, Sarah Sinclair, Kathryn J. Chavez, Yoshimi Endo Greer, Brandon Stone, Stanley Lipkowitz, Seth M. Steinberg
Publikováno v: Breast Cancer Research and Treatment. 155:235-251
Previously, we found that GST-tagged tumor necrosis factor-related apoptosis inducing ligand preferentially killed triple-negative breast cancer (TNBC) cells with a mesenchymal phenotype by activating death receptor 5 (DR5). The purpose of this study
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0bef039f1cb060f93da3f20e66e591fe
https://doi.org/10.1007/s10549-015-3673-z
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5
Brightfield Proximity Ligation Assay Reveals Both Canonical and Mixed Transforming Growth Factor-β/Bone Morphogenetic Protein Smad Signaling Complexes in Tissue Sections
Autor: Samuel L. Dengler, Catherine M. Conway, Misako Sato, Binwu Tang, Lalage M. Wakefield, Paul K. Goldsmith, Christopher D. Heger, Kathleen C. Flanders, Stephen M. Hewitt
Publikováno v: Journal of Histochemistry and Cytochemistry
Transforming growth factor-β (TGF-β) is an important regulator of cellular homeostasis and disease pathogenesis. Canonical TGF-β signaling occurs through Smad2/3–Smad4 complexes; however, recent in vitro studies suggest that elevated levels of T
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ecf40cd7a99f1b55fbdffab2204a652b
https://doi.org/10.1369/0022155414550163
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6
PLCE1 mRNA and Protein Expression and Survival of Patients with Esophageal Squamous Cell Carcinoma and Gastric Adenocarcinoma
Autor: Chaoyu Wang, Christian C. Abnet, Catherine M. Conway, Nan Hu, Victoria H. Burton, Alisa M. Goldstein, Stephen M. Hewitt, Lemin Wang, Hua Su, Ti Ding, Howard H. Yang, Yi Xu, Philip R. Taylor, Carol Giffen, Wen-Qing Li
Publikováno v: Cancer Epidemiology, Biomarkers & Prevention. 23:1579-1588
Background: Germline genetic variants in PLCE1 (10q23) have demonstrated consistent associations with risk of esophageal squamous cell carcinoma (ESCC) and gastric cancer among Chinese. We evaluated PLCE1 mRNA and protein expression in paired tumor-n
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2faef8f5d2480c190f89123b7d225818
https://doi.org/10.1158/1055-9965.epi-13-1329
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7
Profiling of Phospho-AKT, Phospho-mTOR, Phospho-MAPK and EGFR in Non-small Cell Lung Cancer
Autor: Yoshinori Doki, Mikiko Takikita, Joon-Yong Chung, Junya Fukuoka, Catherine M. Conway, Haruhisa Kitano, Stephen M. Hewitt, Kris Ylaya, Jun Hanaoka
Publikováno v: Journal of Histochemistry and Cytochemistry
Activation of numerous pathways has been documented in non-small cell lung cancer (NSCLC). Epidermal growth factor receptor (EGFR) has emerged as a common therapeutic target. The mitogen-activated protein kinase (MAPK) and AKT signaling pathways are
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f846ac459c15b4185e148374bbe1290
https://doi.org/10.1369/0022155414523022
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8
Breast cancer susceptibility risk associations and heterogeneity by E-cadherin tumor tissue expression
Autor: Hisani N. Horne, Douglas F. Easton, Jonine D. Figueroa, Paul D.P. Pharoah, Sarah-Jane Dawson, Ludmila Prokunina-Olsson, Carlos Caldas, Louise A. Brinton, Fiona M. Blows, Montserrat Garcia-Closas, Stephen M. Hewitt, Jolanta Lissowska, Mark E. Sherman, Catherine M. Conway, Stephen J. Chanock, Xiaohong R. Yang
Publikováno v: Breast Cancer Research and Treatment. 143:181-187
E-cadherin is involved in cell-cell adhesion and epithelial-to-mesenchymal transitions (EMT). In cancers, loss or inactivation of E-cadherin is associated with epithelial cell proliferation and invasion. Here, we sought to determine if risk associati
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90c9266a5e2557a9075e33fb6a2ffefb
https://doi.org/10.1007/s10549-013-2771-z
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10
Morphometry Predicts Early GFR Change in Primary Proteinuric Glomerulopathies: A Longitudinal Cohort Study Using Generalized Estimating Equations
Autor: Catherine M. Conway, Laura Barisoni, Peter X.-K. Song, Cynthia C. Nast, Kevin V. Lemley, Serena M. Bagnasco, Stephen M. Hewitt
Publikováno v: PLoS ONE
PLoS ONE, Vol 11, Iss 6, p e0157148 (2016)
Objective Most predictive models of kidney disease progression have not incorporated structural data. If structural variables have been used in models, they have generally been only semi-quantitative. Methods We examined the predictive utility of qua
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f2cad1ffe3b53ac8ed3a168ffba8cdcd
http://europepmc.org/articles/PMC4902229
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