Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Catherine M Clinton"'
Autor:
Andrew L Hong, Yuen-Yi Tseng, Jeremiah A Wala, Won-Jun Kim, Bryan D Kynnap, Mihir B Doshi, Guillaume Kugener, Gabriel J Sandoval, Thomas P Howard, Ji Li, Xiaoping Yang, Michelle Tillgren, Mahmhoud Ghandi, Abeer Sayeed, Rebecca Deasy, Abigail Ward, Brian McSteen, Katherine M Labella, Paula Keskula, Adam Tracy, Cora Connor, Catherine M Clinton, Alanna J Church, Brian D Crompton, Katherine A Janeway, Barbara Van Hare, David Sandak, Ole Gjoerup, Pratiti Bandopadhayay, Paul A Clemons, Stuart L Schreiber, David E Root, Prafulla C Gokhale, Susan N Chi, Elizabeth A Mullen, Charles WM Roberts, Cigall Kadoch, Rameen Beroukhim, Keith L Ligon, Jesse S Boehm, William C Hahn
Publikováno v:
eLife, Vol 8 (2019)
Renal medullary carcinoma (RMC) is a rare and deadly kidney cancer in patients of African descent with sickle cell trait. We have developed faithful patient-derived RMC models and using whole-genome sequencing, we identified loss-of-function intronic
Externí odkaz:
https://doaj.org/article/ea9c3a1d96864bb8bbdbc626e575f019
Autor:
Karuna Mittal, Garrett W. Cooper, Benjamin P. Lee, Yongdong Su, Katie T. Skinner, Jenny Shim, Hunter C. Jonus, Won Jun Kim, Mihir Doshi, Diego Almanza, Bryan D. Kynnap, Amanda L. Christie, Xiaoping Yang, Glenn S. Cowley, Brittaney A. Leeper, Christopher L. Morton, Bhakti Dwivedi, Taylor Lawrence, Manali Rupji, Paula Keskula, Stephanie Meyer, Catherine M. Clinton, Manoj Bhasin, Brian D. Crompton, Yuen-Yi Tseng, Jesse S. Boehm, Keith L. Ligon, David E. Root, Andrew J. Murphy, David M. Weinstock, Prafulla C. Gokhale, Jennifer M. Spangle, Miguel N. Rivera, Elizabeth A. Mullen, Kimberly Stegmaier, Kelly C. Goldsmith, William C. Hahn, Andrew L. Hong
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-13 (2024)
Abstract Wilms tumor (WT) is the most common renal malignancy of childhood. Despite improvements in the overall survival, relapse occurs in ~15% of patients with favorable histology WT (FHWT). Half of these patients will succumb to their disease. Ide
Externí odkaz:
https://doaj.org/article/0c944d44150c49a0b8aca89a9d8db85d
Autor:
David S. Shulman, Lulla V. Kiwinda, Stacey Edwards, Catherine M. Clinton, Sarah Hunt, Lianne Greenspan, Kristen D. Lawler, Gregory Reaman, Hasan Al‐Sayegh, Kira Bona, Allison F. O'Neill, Suzanne Shusterman, Katherine A. Janeway, Andrew E. Place, Susan N. Chi, Clement Ma, Steven G. DuBois
Publikováno v:
Cancer Medicine, Vol 10, Iss 7, Pp 2310-2318 (2021)
Abstract Background Single patient Investigational New Drug (IND) applications are one mechanism through which experimental therapies are accessed for children with cancer. The landscape of use, outcomes, and toxicity from single patient INDs remains
Externí odkaz:
https://doaj.org/article/a55985f140e94952817cff413dfa8e6f
Autor:
Alanna J. Church, Laura B. Corson, Pei-Chi Kao, Alma Imamovic-Tuco, Deirdre Reidy, Duong Doan, Wenjun Kang, Navin Pinto, Luke Maese, Theodore W. Laetsch, AeRang Kim, Susan I. Colace, Margaret E. Macy, Mark A. Applebaum, Rochelle Bagatell, Amit J. Sabnis, Daniel A. Weiser, Julia L. Glade-Bender, Alan C. Homans, John Hipps, Haley Harris, Danielle Manning, Alyaa Al-Ibraheemi, Yvonne Li, Hersh Gupta, Andrew D. Cherniack, Ying-Chun Lo, Gianna R. Strand, Lobin A. Lee, R. Seth Pinches, Lorena Lazo De La Vega, Maegan V. Harden, Niall J. Lennon, Seong Choi, Hannah Comeau, Marian H. Harris, Suzanne J. Forrest, Catherine M. Clinton, Brian D. Crompton, Junne Kamihara, Laura E. MacConaill, Samuel L. Volchenboum, Neal I. Lindeman, Eliezer Van Allen, Steven G. DuBois, Wendy B. London, Katherine A. Janeway
Publikováno v:
Nature Medicine. 28:1581-1589
To evaluate the clinical impact of molecular tumor profiling (MTP) with targeted sequencing panel tests, pediatric patients with extracranial solid tumors were enrolled in a prospective observational cohort study at 12 institutions. In the 345-patien
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e75b332c2f85a30c85057cb884374062
https://doi.org/10.1038/s41591-022-01856-6
https://doi.org/10.1038/s41591-022-01856-6
Autor:
Kimberly Stegmaier, Mignon L. Loh, Marian H. Harris, Jeffrey W. Tyner, Lewis B. Silverman, Katherine A. Janeway, Lia Gore, Neal I. Lindeman, Annette S. Kim, Stephen P. Hunger, Alexandre Puissant, Andrew E. Place, Elliot Stieglitz, Katherine Tarlock, Amy Saur Conway, Amanda L. Robichaud, Angela Su, Neekesh V. Dharia, Matthew P. Jacobson, Diego Garrido Ruiz, Wilian A. Cortopassi, Anjali Cremer, Cristina F. Contreras, Haley L. Faust, Tasleema Patel, Cristina E. Tognon, Alma Imamovic, Shan Lin, Yuting Li, Giacomo Gotti, Nicole Ocasio-Martinez, Catherine M. Clinton, Asmani A. Adhav, Lisa Gennarini, Jeffrey A. Magee, Matthew J. Barth, Jing Chen, Justine M. Kahn, Peter D. Cole, Neerav N. Shukla, Jennifer L. McNeer, Nathan Gossai, Patrick A. Brown, Michael J. Burke, Kelly W. Maloney, Melinda Pauly, Todd M. Cooper, Beth Apsel Winger, Traci M. Blonquist, Kristen Stevenson, Maria Luisa Sulis, Sarah K. Tasian, Yana Pikman
VAF concordance
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af2308b569bf84862a17582216b3dc26
https://doi.org/10.1158/2159-8290.22540342
https://doi.org/10.1158/2159-8290.22540342
Autor:
Kimberly Stegmaier, Mignon L. Loh, Marian H. Harris, Jeffrey W. Tyner, Lewis B. Silverman, Katherine A. Janeway, Lia Gore, Neal I. Lindeman, Annette S. Kim, Stephen P. Hunger, Alexandre Puissant, Andrew E. Place, Elliot Stieglitz, Katherine Tarlock, Amy Saur Conway, Amanda L. Robichaud, Angela Su, Neekesh V. Dharia, Matthew P. Jacobson, Diego Garrido Ruiz, Wilian A. Cortopassi, Anjali Cremer, Cristina F. Contreras, Haley L. Faust, Tasleema Patel, Cristina E. Tognon, Alma Imamovic, Shan Lin, Yuting Li, Giacomo Gotti, Nicole Ocasio-Martinez, Catherine M. Clinton, Asmani A. Adhav, Lisa Gennarini, Jeffrey A. Magee, Matthew J. Barth, Jing Chen, Justine M. Kahn, Peter D. Cole, Neerav N. Shukla, Jennifer L. McNeer, Nathan Gossai, Patrick A. Brown, Michael J. Burke, Kelly W. Maloney, Melinda Pauly, Todd M. Cooper, Beth Apsel Winger, Traci M. Blonquist, Kristen Stevenson, Maria Luisa Sulis, Sarah K. Tasian, Yana Pikman
Supplementary Data file including supplementary methods and clinical case vignettes.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86c0311aeb1a0009a59599a4f819d9ed
https://doi.org/10.1158/2159-8290.22540321.v1
https://doi.org/10.1158/2159-8290.22540321.v1
Autor:
Kimberly Stegmaier, Mignon L. Loh, Marian H. Harris, Jeffrey W. Tyner, Lewis B. Silverman, Katherine A. Janeway, Lia Gore, Neal I. Lindeman, Annette S. Kim, Stephen P. Hunger, Alexandre Puissant, Andrew E. Place, Elliot Stieglitz, Katherine Tarlock, Amy Saur Conway, Amanda L. Robichaud, Angela Su, Neekesh V. Dharia, Matthew P. Jacobson, Diego Garrido Ruiz, Wilian A. Cortopassi, Anjali Cremer, Cristina F. Contreras, Haley L. Faust, Tasleema Patel, Cristina E. Tognon, Alma Imamovic, Shan Lin, Yuting Li, Giacomo Gotti, Nicole Ocasio-Martinez, Catherine M. Clinton, Asmani A. Adhav, Lisa Gennarini, Jeffrey A. Magee, Matthew J. Barth, Jing Chen, Justine M. Kahn, Peter D. Cole, Neerav N. Shukla, Jennifer L. McNeer, Nathan Gossai, Patrick A. Brown, Michael J. Burke, Kelly W. Maloney, Melinda Pauly, Todd M. Cooper, Beth Apsel Winger, Traci M. Blonquist, Kristen Stevenson, Maria Luisa Sulis, Sarah K. Tasian, Yana Pikman
Reasons for not using recommended targeted therapy.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8cab102a90ac6f492696833db0b07120
https://doi.org/10.1158/2159-8290.22540312
https://doi.org/10.1158/2159-8290.22540312
Autor:
Kimberly Stegmaier, Mignon L. Loh, Marian H. Harris, Jeffrey W. Tyner, Lewis B. Silverman, Katherine A. Janeway, Lia Gore, Neal I. Lindeman, Annette S. Kim, Stephen P. Hunger, Alexandre Puissant, Andrew E. Place, Elliot Stieglitz, Katherine Tarlock, Amy Saur Conway, Amanda L. Robichaud, Angela Su, Neekesh V. Dharia, Matthew P. Jacobson, Diego Garrido Ruiz, Wilian A. Cortopassi, Anjali Cremer, Cristina F. Contreras, Haley L. Faust, Tasleema Patel, Cristina E. Tognon, Alma Imamovic, Shan Lin, Yuting Li, Giacomo Gotti, Nicole Ocasio-Martinez, Catherine M. Clinton, Asmani A. Adhav, Lisa Gennarini, Jeffrey A. Magee, Matthew J. Barth, Jing Chen, Justine M. Kahn, Peter D. Cole, Neerav N. Shukla, Jennifer L. McNeer, Nathan Gossai, Patrick A. Brown, Michael J. Burke, Kelly W. Maloney, Melinda Pauly, Todd M. Cooper, Beth Apsel Winger, Traci M. Blonquist, Kristen Stevenson, Maria Luisa Sulis, Sarah K. Tasian, Yana Pikman
Patient sequencing data, by patient number and diagnosis.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac21b42c8423c3474e2acf11d8eb651a
https://doi.org/10.1158/2159-8290.22540324
https://doi.org/10.1158/2159-8290.22540324
Autor:
Katherine A. Janeway, Alanna J. Church, Natalie Collins, Elizabeth Mullen, Nicole R. LeBoeuf, Patrick J. Leavey, Steven G. DuBois, Susan N. Chi, Cigall Kadoch, R. Seth Pinches, Juan Putra, Catherine M. Clinton, Abigail Ward, Duong Doan, Alyaa Al-Ibraheemi, Suzanne J. Forrest
Table S1 shows PD-L1, CD8 and CD163 staining in INI1-negative tumors
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79db95b40eacff5665852c11c6afd9d1
https://doi.org/10.1158/1078-0432.22475259.v1
https://doi.org/10.1158/1078-0432.22475259.v1
Autor:
Katherine A. Janeway, Alanna J. Church, Natalie Collins, Elizabeth Mullen, Nicole R. LeBoeuf, Patrick J. Leavey, Steven G. DuBois, Susan N. Chi, Cigall Kadoch, R. Seth Pinches, Juan Putra, Catherine M. Clinton, Abigail Ward, Duong Doan, Alyaa Al-Ibraheemi, Suzanne J. Forrest
Figure S1 shows Tier 1-3 genomic events in INI1-negative tumors
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f4b8632987760b7cd5ce5771cdb331d
https://doi.org/10.1158/1078-0432.22475265.v1
https://doi.org/10.1158/1078-0432.22475265.v1