Výsledky vyhledávání - "Catherine Ménard"

miR-106b suppresses pathological retinal angiogenesis

Autor: Francois Binet, Rachel Juneau, Catherine Ménard, Agnieszka Dejda, Frédérique Pilon, Célia Parinot, Khalil Miloudi, John Paul SanGiovanni, Gaelle Mawambo, Sergio Crespo-Garcia, Przemyslaw Sapieha, Elisabeth M M A Andriessen, Ariel M. Wilson, Vincent De Guire

Publikováno v: Aging (Albany NY)

MicroRNAs are small non-coding RNAs that post-transcriptionally regulate gene expression. We recently demonstrated that levels of miR-106b were significantly decreased in the vitreous and plasma of patients with neovascular age-related macular degene

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb1a92d4ee147bcc34f2ef512b7683bb
https://doi.org/10.18632/aging.202404

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NOTCH1 signaling induces pathological vascular permeability in diabetic retinopathy

Publikováno v: Proceedings of the National Academy of Sciences. 116:4538-4547

Diabetic macular edema is a major complication of diabetes resulting in loss of central vision. Although heightened vessel leakiness has been linked to glial and neuronal-derived factors, relatively little is known on the mechanisms by which mature e

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e533eb565411f9922cfd6bc9003d32d9
https://doi.org/10.1073/pnas.1814711116

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How does physicians' decisional conflict influence their ability to address treatment outcomes in a decision-making encounter with an advanced-stage cancer simulated patient? A descriptive study

Autor: Darius Razavi, Delphine Canivet, Jean-Louis Slachmuylder, Christine Farvacques, Aurore Liénard, Yves Libert, Isabelle Merckaert, Livia Peternelj, Christine Reynaert, Catherine Ménard

Publikováno v: Patient education and counseling, Vol. 103, no. 9, p. 1752-1759 (2020)
Patient education and counseling

Objectives: This descriptive study assesses how physicians’ decisional conflict influences their ability to address treatment outcomes (TOs) in a decision-making encounter with an advanced-stage cancer simulated patient (SP). Methods: Physicians (N

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a94d57bef59b55e2cb5f9533489efc62
https://hdl.handle.net/2078.1/230777

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Predictors of physicians’ communication performance in a decision-making encounter with a simulated advanced-stage cancer patient: A longitudinal study

Autor: Catherine Ménard, Aurore Liénard, Laetitia Van Achte, Christine Farvacques, Christine Reynaert, Jean Klastersky, Isabelle Merckaert, Darius Razavi, Nicole Delvaux, Yves Libert, Jean-Louis Slachmuylder, Jean-François Durieux, Delphine Canivet

Publikováno v: Patient Education and Counseling. 100:1672-1679

Physicians' characteristics that influence their communication performance (CP) in decision-making encounters have been rarely studied. In this longitudinal study, predictors of physicians' CP were investigated with a simulated advanced-stage cancer

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::391834f0e59766ef32a51fdaae690235
https://doi.org/10.1016/j.pec.2017.02.025

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B7-H7 (HHLA2) inhibits T-cell activation and proliferation in the presence of TCR and CD28 signaling

Autor: Catherine Ménard, Jodi L. Karnell, Christopher E. Rudd, Sadiye Amcaoglu Rieder, Jingya Wang, Geoffrey Stephens, Ariful Qadri, Roland Kolbeck, Natalie White

Publikováno v: Cellular and Molecular Immunology

Modulation of T-cell responses has played a key role in treating cancers and autoimmune diseases. Therefore, understanding how different receptors on T cells impact functional outcomes is crucial. The influence of B7-H7 (HHLA2) and CD28H (TMIGD2) on

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd753f1a59d1a8029b605b2176af8084
https://pubmed.ncbi.nlm.nih.gov/32005952

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MicroRNA signatures in vitreous humour and plasma of patients with exudative AMD

Autor: John Paul SanGiovanni, Pierre Hardy, Flavio A. Rezende, Vincent De Guire, Khalil Miloudi, Catherine Ménard, Ariel M. Wilson, Nicolas Tetreault, Przemyslaw Sapieha

Publikováno v: Oncotarget

Age-related macular degeneration (AMD) is a leading cause of blindness worldwide affecting individuals over the age of 50. The neovascular form (NV AMD) is characterized by choroidal neovascularization (CNV) and responsible for the majority of centra

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ccfc2d50ed1e6c8dfc685d3594e685f
https://doi.org/10.18632/oncotarget.8280

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Neuropilin-1 mediates myeloid cell chemoattraction and influences retinal neuroimmune crosstalk

Autor: Catherine Ménard, Sullivan Henriques, Agnieszka Dejda, Przemyslaw Sapieha, Nathalie Labrecque, Felix Beaudoin, Khalil Miloudi, Flavio A. Rezende, Agustin Cerani, Naoufal Akla, Salix Boulet, Jean-Sébastien Delisle, Malika Oubaha, Gaelle Mawambo, Jean-François Daudelin, Andreas Stahl, Zhuo Shao

Publikováno v: Journal of Clinical Investigation. 124:4807-4822

Immunological activity in the CNS is largely dependent on an innate immune response and is heightened in diseases, such as diabetic retinopathy, multiple sclerosis, amyotrophic lateral sclerosis, and Alzheimer’s disease. The molecular dynamics gove

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7cc6ac08fdc340b07abdd0a9681eb1ca
https://doi.org/10.1172/jci76492

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Neuron-Derived Semaphorin 3A Is an Early Inducer of Vascular Permeability in Diabetic Retinopathy via Neuropilin-1

Autor: Dominique Leboeuf, Chintan Patel, Khalil Miloudi, Vincent De Guire, Nicolas Tetreault, Agnieszka Dejda, Przemyslaw Sapieha, Agustin Cerani, Catherine Ménard, Felix Beaudoin, Francois Binet, Flavio A. Rezende, Eric Lapalme, Nicholas Sitaras

Publikováno v: Cell Metabolism. 18(4):505-518

SummaryThe deterioration of the inner blood-retinal barrier and consequent macular edema is a cardinal manifestation of diabetic retinopathy (DR) and the clinical feature most closely associated with loss of sight. We provide evidence from both human

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::655a94015d7e98261d9633bba264aae3

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Circulating miRNAs as sensitive and specific biomarkers for the diagnosis and monitoring of human diseases: Promises and challenges

Autor: N. Bambace, Przemyslaw Sapieha, V. De Guire, Richard Robitaille, Catherine Ménard, Nicolas Tetreault, Renée Guérin

Publikováno v: Clinical Biochemistry. 46:846-860

The regulation and modulation of gene expression has been a central focus of modern biomedical research ever since the first molecular elucidation of DNA. The cellular mechanisms by which genes are expressed and repressed hold valuable insight for ma

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f46eb4eb2426fa6bebe1eaf9cecb25d6
https://doi.org/10.1016/j.clinbiochem.2013.03.015

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