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pro vyhledávání: '"Catherine Ludlow"'
Autor:
S Goehle, Julian A. Simon, John R. Lamb, Philippe Szankasi, Catherine Ludlow, David R. H. Evans, Heather M. Dunstan, Michelle Cronk
Publikováno v:
JNCI Journal of the National Cancer Institute. 94:88-94
Background: We are developing cell-based assays to identify anticancer agents that are selectively toxic to cells with defined mutations. As a test, we used a three-stage strategy to screen compounds from the National Cancer Institute’s repository
Autor:
Gregory A, Cary, Sung Hwan, Yoon, Cecilia Garmendia, Torres, Kathie, Wang, Michelle, Hays, Catherine, Ludlow, David R, Goodlett, Aimée M, Dudley
Publikováno v:
Yeast (Chichester, England). 31(5)
Puromycin is an aminonucleoside antibiotic with structural similarity to aminoacyl tRNA. This structure allows the drug to bind the ribosomal A-site and incorporate into nascent polypeptides causing chain termination, ribosomal subunit dissociation,