Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Catherine Lecoffre"'
Autor:
Christopher N. Berry, Jean-Michel Altenburger, Christian Pfersdorff, Frédérique Guilbert, Stephen E. O'Connor, Catherine Lunven, Jean-Pascal Herault, Lassalle Gilbert, Alain Lalé, Jean-Marc Herbert, Catherine Lecoffre
Publikováno v:
Journal of Pharmacology and Experimental Therapeutics. 303:1189-1198
SSR182289A competitively inhibits human thrombin (K(i) = 0.031 +/- 0.002 microM) and shows good selectivity with respect to other human proteases, e.g., trypsin (K(i) = 54 +/- 2 microM), factor Xa (K(i) = 167 +/- 9 microM), and factor VIIa, factor IX
Autor:
Nigel O. Roome, Catherine Lunven, Catherine Lecoffre, Bénédicte Roger, Nathalie Vivan, Danielle Garrigou-Gadenne, Christopher N. Berry, Pierre Lainée, Alain Rouchouse, Stephen E. O'Connor, Frederic Andre
Publikováno v:
Thrombosis and Haemostasis. 84:278-285
SummaryWe have studied the anticoagulant properties of a novel mixed micellar formulation containing 14 mg/ml argatroban administered by the sub-cutaneous (s. c.) route to rats, rabbits, dogs and primates. Blood samples were taken at various times po
Publikováno v:
Thrombosis and Haemostasis. 84:286-290
SummaryWe studied the antithrombotic activity of a mixed micellar formulation containing 14 mg/ml argatroban administered by the subcutaneous (s. c.) route in rat and rabbit models of venous thrombosis. The effects on bleeding time in the rat tail tr
Autor:
Catherine Lecoffre, Donogh P. O’Brien, Christiane Gauffeny, Catherine Lunven, Nigel O. Roome, Christopher N. Berry
Publikováno v:
Thrombosis and Haemostasis. 75:154-169
SummaryClot-associated thrombin retains amidolytic activity, and is resistant to inhibition by heparin, but not to low molecular weight thrombin inhibitors. We show that clot-associated thrombin induces platelet aggregation, is resistant to heparin:a
Publikováno v:
Thrombosis and Haemostasis. 72:381-386
SummaryThe inhibitory effects of argatroban on clot- or fibrin-bound human thrombin were studied using the thrombin-specific chromogenic substrate S2238 (200 μM). These effects were compared to those of recombinant hirudin (rHV2 Lys 47) and the hepa
1. The antithrombotic action of argatroban, a synthetic thrombin inhibitor, was studied in three models of thrombosis in the rat, and in the tail transection bleeding time test. Heparin was studied as a reference anticoagulant. 2. In the model of ven
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6eddf5928b03c9f2a7d6e59a9b6cf3a5
https://europepmc.org/articles/PMC1510499/
https://europepmc.org/articles/PMC1510499/
Autor:
N, Berry Christopher, Gilbert, Lassalle, Catherine, Lunven, Jean-Michel, Altenburger, Frdrique, Guilbert, Alain, Lal, Jean-Pascal, Hrault, Catherine, Lecoffre, Christian, Pfersdorff, Jean-Marc, Herbert, E, O'Connor Stephen
Publikováno v:
The Journal of Pharmacology and Experimental Therapeutics; December 2002, Vol. 303 Issue: 3 p1189-98, 10p