Zobrazeno 1 - 10
of 204
pro vyhledávání: '"Catherine Lacombe"'
Autor:
Meriem Ladli, Cyrielle Richard, Lilia Cantero Aguilar, Sarah Ducamp, Sabrina Bondu, Pierre Sujobert, Jérôme Tamburini, Catherine Lacombe, Nabih Azar, Marc Foretz, Yael Zermati, Patrick Mayeux, Benoit Viollet, Frédérique Verdier
Publikováno v:
Haematologica, Vol 104, Iss 5 (2019)
AMP-activated protein kinase (AMPK) is a heterotrimeric complex containing α, β, and γ subunits involved in maintaining integrity and survival of murine red blood cells. Indeed, Ampk α1−/−, Ampk β1−/− and Ampk γ1−/− mice develop hem
Externí odkaz:
https://doaj.org/article/a9a0e307e321463b82d48aac27127b72
Autor:
Emilie-Fleur Gautier, Sarah Ducamp, Marjorie Leduc, Virginie Salnot, François Guillonneau, Michael Dussiot, John Hale, Marie-Catherine Giarratana, Anna Raimbault, Luc Douay, Catherine Lacombe, Narla Mohandas, Frédérique Verdier, Yael Zermati, Patrick Mayeux
Publikováno v:
Cell Reports, Vol 16, Iss 5, Pp 1470-1484 (2016)
Mass spectrometry-based proteomics now enables the absolute quantification of thousands of proteins in individual cell types. We used this technology to analyze the dynamic proteome changes occurring during human erythropoiesis. We quantified the abs
Externí odkaz:
https://doaj.org/article/f796025f11234209aeda0500f5e4e97a
Autor:
Anne-Sophie Chretien, Raynier Devillier, Cyril Fauriat, Florence Orlanducci, Samia Harbi, Aude Le Roy, Jérôme Rey, Gaelle Bouvier Borg, Emmanuel Gautherot, Jean-François Hamel, Norbert Ifrah, Catherine Lacombe, Pascale Cornillet-Lefebvre, Jacques Delaunay, Antoine Toubert, Christine Arnoulet, Norbert Vey, Didier Blaise, Daniel Olive
Publikováno v:
OncoImmunology, Vol 6, Iss 12 (2017)
NKp46 is a major determinant of natural killer (NK) cell function and it is implicated in tumor immune surveillance in acute myeloid leukemia (AML). The purpose of this study was to investigate the prognostic significance of NKp46 expression in an in
Externí odkaz:
https://doaj.org/article/026f7a891e304af5822521b862fe116b
Autor:
Pierre Sujobert, Laury Poulain, Etienne Paubelle, Florence Zylbersztejn, Adrien Grenier, Mireille Lambert, Elizabeth C. Townsend, Jean-Marie Brusq, Edwige Nicodeme, Justine Decrooqc, Ina Nepstad, Alexa S. Green, Johanna Mondesir, Marie-Anne Hospital, Nathalie Jacque, Alexandra Christodoulou, Tiffany A. Desouza, Olivier Hermine, Marc Foretz, Benoit Viollet, Catherine Lacombe, Patrick Mayeux, David M. Weinstock, Ivan C. Moura, Didier Bouscary, Jerome Tamburini
Publikováno v:
Cell Reports, Vol 11, Iss 9, Pp 1446-1457 (2015)
AMPK is a master regulator of cellular metabolism that exerts either oncogenic or tumor suppressor activity depending on context. Here, we report that the specific AMPK agonist GSK621 selectively kills acute myeloid leukemia (AML) cells but spares no
Externí odkaz:
https://doaj.org/article/9222733afbf84f689b27bbb06ca36d9b
Autor:
Anne-Sophie Chretien, Cyril Fauriat, Florence Orlanducci, Claire Galseran, Jerome Rey, Gaelle Bouvier Borg, Emmanuel Gautherot, Samuel Granjeaud, Jean-François Hamel-Broza, Clemence Demerle, Norbert Ifrah, Catherine Lacombe, Pascale Cornillet-Lefebvre, Jacques Delaunay, Antoine Toubert, Emilie Gregori, Herve Luche, Marie Malissen, Christine Arnoulet, Jacques A. Nunes, Norbert Vey, Daniel Olive
Publikováno v:
Frontiers in Immunology, Vol 8 (2017)
Accumulating evidence highlights natural killer (NK) cell parameters as potential prognostic factors in cancer patients, which provides a strong rationale for developing therapeutic strategies aiming at restoring NK cell. However, reaching this point
Externí odkaz:
https://doaj.org/article/5133576a9c344b3ca9296d66a3c47857
Autor:
Alessia Pagani, Maud Vieillevoye, Antonella Nai, Marco Rausa, Meriem Ladli, Catherine Lacombe, Patrick Mayeux, Frédérique Verdier, Clara Camaschella, Laura Silvestri
Publikováno v:
Haematologica, Vol 100, Iss 4 (2015)
Transferrin receptor-2 is a transmembrane protein whose expression is restricted to hepatocytes and erythroid cells. Transferrin receptor-2 has a regulatory function in iron homeostasis, since its inactivation causes systemic iron overload. Hepatic t
Externí odkaz:
https://doaj.org/article/ba81c6f23436410986e57ec8d5eaa355
Autor:
Christine Chomienne, Shaun McCann, Tony Green, Anton Hagenbeek, Catherine Lacombe, Margarita Guenova, Irene Roberts, Ineke van der Beek
Publikováno v:
Haematologica, Vol 98, Iss 6 (2013)
Externí odkaz:
https://doaj.org/article/dbcf948533604063aae14130b70f1cb1
Quality of Life in hematology: European Hematology Association theme of the year … and years to come
Autor:
Christine Chomienne, Margarita Guenova, Anton Hagenbeek, Catherine Lacombe, Shaun McCann, Sam Salek, Jan Geissler, Ineke van der Beek
Publikováno v:
Haematologica, Vol 98, Iss 1 (2013)
Externí odkaz:
https://doaj.org/article/28e08bc79c5043b781aedcc016068a83
Autor:
Diane D'allard, Julie Gay, Clotilde Descarpentries, Emilie Frisan, Kevin Adam, Frederique Verdier, Célia Floquet, Patrice Dubreuil, Catherine Lacombe, Michaela Fontenay, Patrick Mayeux, Olivier Kosmider
Publikováno v:
PLoS ONE, Vol 8, Iss 4, p e60961 (2013)
The stem cell factor receptor (SCF) c-Kit plays a pivotal role in regulating cell proliferation and survival in many cell types. In particular, c-Kit is required for early amplification of erythroid progenitors, while it must disappear from cell surf
Externí odkaz:
https://doaj.org/article/fa067dc590e84f4ea8744597e596650e
Autor:
François Vergez, Alexa S. Green, Jerome Tamburini, Jean-Emmanuel Sarry, Baptiste Gaillard, Pascale Cornillet-Lefebvre, Melanie Pannetier, Aymeric Neyret, Nicolas Chapuis, Norbert Ifrah, François Dreyfus, Stéphane Manenti, Cecile Demur, Eric Delabesse, Catherine Lacombe, Patrick Mayeux, Didier Bouscary, Christian Recher, Valerie Bardet
Publikováno v:
Haematologica, Vol 96, Iss 12 (2011)
Background Acute myeloid leukemias arise from a rare population of leukemic cells, known as leukemic stem cells, which initiate the disease and contribute to frequent relapses. Although the phenotype of these cells remains unclear in most patients, t
Externí odkaz:
https://doaj.org/article/4cd593019b8b441587d7e540492219c7