Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Catherine L. Silski"'
Publikováno v:
Gene Therapy. 8:586-592
We have used an anti-human polymeric immunoglobulin receptor (plgR) single chain Fv (scFv) to deliver reporter genes to epithelial cells in vitro. The scFv was constructed from a monoclonal antibody directed against plgR and a cysteine residue was ad
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e795e42012301ef02da22b3ad19c9c1
https://doi.org/10.1038/sj.gt.3301451
https://doi.org/10.1038/sj.gt.3301451
Autor:
Catherine L. Silski, Elizabeth Eckman, Tivadar Szegletes, Pamela B. Davis, John R. Schreiber, William D. Mallender, Thomas W. Ferkol
Publikováno v:
American Journal of Respiratory Cell and Molecular Biology. 21:246-252
In cystic fibrosis (CF), the intense host inflammatory response to chronic infection largely accounts for the progressive pulmonary disease, and ultimately death. Neutrophils are the prominent inflammatory cells in the lungs of patients with CF, and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::035687bc3ea847aee29b2abc85fe6953
https://doi.org/10.1165/ajrcmb.21.2.3687
https://doi.org/10.1165/ajrcmb.21.2.3687
Autor:
Stephen E. Alpert, Ronald W. Walenga, Pamela B. Davis, Constance M. Kramer, Catherine L. Silski
Publikováno v:
American Journal of Physiology-Lung Cellular and Molecular Physiology. 262:L192-L197
Tracheal epithelial (TE) cells from both rabbits and humans, when cultured in defined serum-free media without lipid supplements, develop fatty acid profiles significantly different from freshly isolated epithelium, including a markedly decreased cel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92543bd78f151911c9f0fc6b5e310270
https://doi.org/10.1152/ajplung.1992.262.2.l192
https://doi.org/10.1152/ajplung.1992.262.2.l192
Publikováno v:
American journal of respiratory and critical care medicine. 161(3 Pt 1)
Neutrophil elastase (NE) contributes to progression of the lung disease characteristic of cystic fibrosis (CF). We developed a strategy that permits the delivery of alpha(1)-antitrypsin (alpha(1)-AT) to inaccessible CF airways by targeting the respir
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7cd5e75af2cc4708722067bd495af9df
https://pubmed.ncbi.nlm.nih.gov/10712347
https://pubmed.ncbi.nlm.nih.gov/10712347
Publikováno v:
American journal of respiratory cell and molecular biology. 6(2)
Amiloride, a potent blocker of the sodium channel in airway epithelium, has been administered by aerosol as a therapeutic agent for cystic fibrosis. Because amiloride in high concentration has been reported to interfere with cell functions, including
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::909b391fe63f0acd04488353d146e071
https://pubmed.ncbi.nlm.nih.gov/1347224
https://pubmed.ncbi.nlm.nih.gov/1347224
Publikováno v:
The American journal of physiology. 258(1 Pt 1)
Human tracheal epithelial cells in suspension, whether obtained by brushing at bronchoscopy or from necropsy specimens by proteolytic digestion and EDTA treatment, increase adenosine 3',5'-cyclic monophosphate (cAMP) production in response to isoprot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44b757bc7fc3bd0b5eefe67674427dc0
https://pubmed.ncbi.nlm.nih.gov/1689114
https://pubmed.ncbi.nlm.nih.gov/1689114
Autor:
Catherine L. Silski, Pamela B. Davis
Publikováno v:
Clinical science (London, England : 1979). 73(5)
1. Platelets taken from healthy unmedicated subjects over 65 years of age display less inhibition of prostaglandin E1 (PGE1)-stimulated adenosine 3′:5′-cyclic monophosphate (cyclic AMP) synthesis by noradrenaline than do platelets taken from youn
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e89ccfe57ed61bb3ee9075707ffc57ed
https://pubmed.ncbi.nlm.nih.gov/2824117
https://pubmed.ncbi.nlm.nih.gov/2824117