Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Catherine L. Keck"'
Autor:
Drazen B. Zimonjic, Marian E. Durkin, Catherine L. Keck-Waggoner, Sang-Won Park, Snorri S. Thorgeirsson, Nicholas C. Popescu
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 5, Iss 5, Pp 390-396 (2003)
Signaling by the transforming growth factor (TGF)family members is transduced from the cell surface to the nucleus by the Smad group of intracellular proteins. Because we detected alterations on the long arm of chromosome 5, we examined the status of
Externí odkaz:
https://doaj.org/article/10afa73f6cf54fb08e27a12f0c301a01
Autor:
Sang Won Park, Marian E. Durkin, Drazen B. Zimonjic, Snorri S. Thorgeirsson, Catherine L. Keck-Waggoner, Nicholas C. Popescu
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 5, Iss 5, Pp 390-396 (2003)
Signaling by the transforming growth factor (TGF)-family members is transduced from the cell surface to the nucleus by the Smad group of intracellular proteins. Because we detected alterations on the long arm of chromosome 5, we examined the status o
Autor:
Shioko Kimura, Mitsuru Munakata, Roy C. Levitt, Catherine L. Keck-Waggoner, Michie Hisada, Nicholas C. Popescu, Tomoaki Niimi
Publikováno v:
The American Journal of Human Genetics. 70(3):718-725
Several traits associated with asthma phenotypes, such as high total serum immunoglobulin E and bronchial hyperresponsiveness, have been linked by numerous genome-screen studies and linkage analyses to markers on human chromosome 5q31-q34. In the pre
Autor:
Roy C. Levitt, Tomoaki Niimi, Yuhong Zhou, Catherine L. Keck-Waggoner, Shioko Kimura, Nicholas C. Popescu
Publikováno v:
Molecular Endocrinology. 15:2021-2036
A novel gene that is down-regulated in lungs of T/ebp/Nkx2.1-null mouse embryos has been identified using a suppressive-subtractive hybridization method. The gene product is a secreted protein, forms a homodimer, and exhibits an amino acid sequence s
Publikováno v:
Genomics. 73:20-27
Transgenic mice expressing c-myc under the control of the albumin promoter and enhancer develop liver tumors and have served as a useful model for studying the progression of hepatocarcinogenesis. The chromosomes of one line of c-myc transgenic mice
Autor:
Drazen B. Zimonjic, Nicholas C. Popescu, Catherine L. Keck-Waggoner, E.R. Lemmer, Snorri S. Thorgeirsson, J.L. Welch, T L Tsai, C.-G. Huh
Publikováno v:
Cytogenetic and Genome Research. 89:129-132
The RelA (p65) subunit of transcription factor NF-κB plays a critical role in development, and rela–/– knockout mice die in utero from massive liver apoptosis. Only partial sequences of the mouse Rela gene are available. We have determined the g
Autor:
Matthew V. Lorenzi, Toru Miki, Paola Castagnino, Catherine L. Keck, Chong Chou Lee, David C. Lieb, Daniel C. Aaronson, Nicholas C. Popescu
Publikováno v:
Genomics. 62:59-66
We have previously identified a chromosomal rearrangement between fibroblast growth factor receptor 2 (FGFR2) and a novel gene, FRAG1, in a rodent model of osteosarcoma. To assess the potential role of FRAG1 in disease further, we have isolated cDNA
Autor:
Nadia Wang, Anil B. Mukherjee, Catherine L. Keck, Nicholas C. Popescu, Zhongjian Zhang, Asim K. Mandal, Drazen B. Zimonjic
Publikováno v:
Gene. 231:203-211
Mutations in the palmitoyl-protein thioesterase (PPT) gene cause infantile neuronal ceroid lipofuscinosis (INCL), the clinical manifestations of which include the early loss of vision followed by deterioration of brain functions. To gain insight into
Publikováno v:
Hepatology. 29:1208-1214
To search for recurrent and specific genomic alterations in human hepatocellular carcinoma (HCC), we examined 18 cell lines by comparative genomic hybridization (CGH), a molecular cytogenetic approach that allows positional identification of gains an
Autor:
Svetlana Pack, Michael I. Lerman, Ming Hui Wei, Jonathan A. Eisen, Catherine L. Keck, Irina Karavanova, Sergey Ivanov, Nicolae C. Popescu
Publikováno v:
Human Genetics. 103:355-364
To discover genes contributing to mental retardation in 3p- syndrome patients we have used in silico searches for neural genes in NCBI databases (dbEST and Uni-Gene). An EST with strong homology to the rat CAM L1 gene subsequently mapped to 3p26 was