Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Catherine L. Hunt"'
Publikováno v:
Viruses, Vol 4, Iss 2, Pp 258-275 (2012)
Ebolavirus (EBOV) and Marburgvirus (MARV) that compose the filovirus family of negative strand RNA viruses infect a broad range of mammalian cells. Recent studies indicate that cellular entry of this family of viruses requires a series of cellular pr
Externí odkaz:
https://doaj.org/article/91bbea209d514c26a69b4f9925dd49c6
Autor:
Daren S. Mueller, Laura E. Lindsey, William J. Ross, Martin I. Chilvers, Seth L. Naeve, Dominic D. Reisig, Adam M. Byrne, Shawn P. Conley, Yuba R. Kandel, Adam J. Varenhorst, Maciej J. Kazula, Paul D. Esker, Sean Malone, Sally V. Taylor, Devon R. Rossman, Ames Herbert, Loren J. Giesler, Nicholas J. Arneson, Spyridon Mourtzinis, Emerson D. Nafziger, Christian H. Krupke, Carl A. Bradley, Catherine L. Hunt
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-7 (2019)
Scientific Reports
Scientific Reports
Neonicotinoids are the most widely used insecticides worldwide and are typically deployed as seed treatments (hereafter NST) in many grain and oilseed crops, including soybeans. However, there is a surprising dearth of information regarding NST effec
Publikováno v:
Journal of Virology
Identification of host factors that are needed for Zaire Ebolavirus (EBOV) entry provides insights into the mechanism(s) of filovirus uptake, and these factors may serve as potential antiviral targets. In order to identify novel host genes and pathwa
Autor:
Patrick L. Sinn, Andrew S. Kondratowicz, Melinda A. Brindley, Kathrina Quinn, John A. Chiorini, Wendy Maury, Catherine L. Hunt, Melodie L. Weller, Jill Bowman, Paul B. McCray
Publikováno v:
Virology
In a bioinformatics-based screen for cellular genes that enhance Zaire ebolavirus (ZEBOV) transduction, AXL mRNA expression strongly correlated with ZEBOV infection. A series of cell lines and primary cells were identified that require Axl for optima
Autor:
Paul B. McCray, Kathrina Quinn, Patrick L. Sinn, Robert A. Davey, David K. Meyerholz, Andrew S. Kondratowicz, Wendy Maury, Sven Moller-Tank, Robert F. Mullins, Lindsay M Sandersfeld, Melodie L. Weller, Paul D. Rennert, Melinda A. Brindley, John A. Chiorini, Nicholas J. Lennemann, Catherine L. Hunt
Publikováno v:
Proceedings of the National Academy of Sciences
The glycoproteins (GP) of enveloped viruses facilitate entry into the host cell by interacting with specific cellular receptors. Despite extensive study, a cellular receptor for the deadly filoviruses Ebolavirus and Marburgvirus has yet to be identif
Publikováno v:
Journal of virology. 85(1)
Axl, a plasma membrane-associated Tyro3/Axl/Mer (TAM) family member, is necessary for optimal Zaire ebolavirus (ZEBOV) glycoprotein (GP)-dependent entry into some permissive cells but not others. To date, the role of Axl in virion entry is unknown. T
Autor:
John A. Chiorini, William R. Staplin, Melinda A. Brindley, Ramon Flick, Beverly L. Davidson, Catherine L. Hunt, Andrew S. Kondratowicz, Melodie L. Weller, Patrick L. Sinn, Kathrina Quinn, Paul B. McCray, Nikola Kaludov, Colleen S. Stein, Wendy Maury, Robert Mandell
Publikováno v:
Journal of virology. 83(19)
To explore mechanisms of entry for Ebola virus (EBOV) glycoprotein (GP) pseudotyped virions, we used comparative gene analysis to identify genes whose expression correlated with viral transduction. Candidate genes were identified by using EBOV GP pse
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 176(8)
Invading bacteria such as Staphylococcus aureus induce mobilization of professional phagocytes (e.g., neutrophils) and extracellular antibacterial proteins (e.g., group IIA phospholipase A2 (gIIA PLA2)). Accumulation of gIIA PLA2 in inflammatory flui