Zobrazeno 1 - 10
of 249
pro vyhledávání: '"Catherine L. Drennan"'
Autor:
Sheena Vasquez, Melissa D. Marquez, Edward J. Brignole, Amanda Vo, Sunnie Kong, Christopher Park, Deborah L. Perlstein, Catherine L. Drennan
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-12 (2023)
Abstract Iron-sulfur clusters are essential for life and defects in their biosynthesis lead to human diseases. The mechanism of cluster assembly and delivery to cytosolic and nuclear client proteins via the cytosolic iron-sulfur cluster assembly (CIA
Externí odkaz:
https://doaj.org/article/02d17a462c754d74bb13a10be64ddd48
Autor:
Mary C. Andorfer, Devin T. King-Roberts, Christa N. Imrich, Balyn G. Brotheridge, Catherine L. Drennan
Publikováno v:
iScience, Vol 26, Iss 6, Pp 106902- (2023)
Summary: Anaerobic microbial degradation of hydrocarbons is often initiated through addition of the hydrocarbon to fumarate by enzymes known as X-succinate synthases (XSSs). XSSs use a glycyl radical cofactor, which is installed by an activating enzy
Externí odkaz:
https://doaj.org/article/7f0ec84e99054e999b06e030f6a72697
Publikováno v:
ACS Omega, Vol 6, Iss 21, Pp 13756-13765 (2021)
Externí odkaz:
https://doaj.org/article/3ad335d243f243cf85de2b387f0e7f5b
Autor:
Talya S. Levitz, Miriam Weckener, Ivan Fong, James H. Naismith, Catherine L. Drennan, Edward J. Brignole, Daniel K. Clare, Michele C. Darrow
Publikováno v:
Frontiers in Molecular Biosciences, Vol 9 (2022)
The specimen preparation process is a key determinant in the success of any cryo electron microscopy (cryoEM) structural study and until recently had remained largely unchanged from the initial designs of Jacques Dubochet and others in the 1980s. The
Externí odkaz:
https://doaj.org/article/b2580e688193450db37856df424dbc9b
Autor:
Talya S. Levitz, Gisele A. Andree, Rohan Jonnalagadda, Christopher D. Dawson, Rebekah E. Bjork, Catherine L. Drennan
Publikováno v:
PLoS ONE, Vol 17, Iss 6 (2022)
Ribonucleotide reductases (RNRs) use radical-based chemistry to catalyze the conversion of all four ribonucleotides to deoxyribonucleotides. The ubiquitous nature of RNRs necessitates multiple RNR classes that differ from each other in terms of the p
Externí odkaz:
https://doaj.org/article/52003eb3d4d54b7ea8f8b02ebfa4a81f
Autor:
Kimberly Rizzolo, Steven E. Cohen, Andrew C. Weitz, Madeline M. López Muñoz, Michael P. Hendrich, Catherine L. Drennan, Sean J. Elliott
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-10 (2019)
The diheme enzyme MauG forms a bis-Fe(IV) state. Here the authors identify and determine the structure of BthA, a diheme peroxidase conserved in all Burkholderia and show that BthA also forms a bis-Fe(IV) species but mechanistically differs from MauG
Externí odkaz:
https://doaj.org/article/43e89e2788134c44bc04e90574efd768
Autor:
Peter A. Meyer, Stephanie Socias, Jason Key, Elizabeth Ransey, Emily C. Tjon, Alejandro Buschiazzo, Ming Lei, Chris Botka, James Withrow, David Neau, Kanagalaghatta Rajashankar, Karen S. Anderson, Richard H. Baxter, Stephen C. Blacklow, Titus J. Boggon, Alexandre M. J. J. Bonvin, Dominika Borek, Tom J. Brett, Amedeo Caflisch, Chung-I Chang, Walter J. Chazin, Kevin D. Corbett, Michael S. Cosgrove, Sean Crosson, Sirano Dhe-Paganon, Enrico Di Cera, Catherine L. Drennan, Michael J. Eck, Brandt F. Eichman, Qing R. Fan, Adrian R. Ferré-D'Amaré, J. Christopher Fromme, K. Christopher Garcia, Rachelle Gaudet, Peng Gong, Stephen C. Harrison, Ekaterina E. Heldwein, Zongchao Jia, Robert J. Keenan, Andrew C. Kruse, Marc Kvansakul, Jason S. McLellan, Yorgo Modis, Yunsun Nam, Zbyszek Otwinowski, Emil F. Pai, Pedro José Barbosa Pereira, Carlo Petosa, C. S. Raman, Tom A. Rapoport, Antonina Roll-Mecak, Michael K. Rosen, Gabby Rudenko, Joseph Schlessinger, Thomas U. Schwartz, Yousif Shamoo, Holger Sondermann, Yizhi J. Tao, Niraj H. Tolia, Oleg V. Tsodikov, Kenneth D. Westover, Hao Wu, Ian Foster, James S. Fraser, Filipe R. N C. Maia, Tamir Gonen, Tom Kirchhausen, Kay Diederichs, Mercè Crosas, Piotr Sliz
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-12 (2016)
The validation and analysis of X-ray crystallographic data is essential for reproducibility and the development of crystallographic methods. Here, the authors describe a repository for crystallographic datasets and demonstrate some of the ways it cou
Externí odkaz:
https://doaj.org/article/72383da3679147f9a2668c703d709d2e
Autor:
Sean J. Elliott, Nicholas C. Bene, Catherine L. Drennan, Marco Jost, Cintyu Wong, Michael J. Hamill
Publikováno v:
International Journal of Molecular Sciences, Vol 13, Iss 12, Pp 16899-16915 (2012)
When exposed to known DNA-damaging alkylating agents, Escherichia coli cells increase production of four DNA repair enzymes: Ada, AlkA, AlkB, and AidB. The role of three enzymes (Ada, AlkA, and AlkB) in repairing DNA lesions has been well characteriz
Externí odkaz:
https://doaj.org/article/36ec6e4c54724e22b60f31b517989f26
Autor:
Elizabeth Taylor, Catherine L. Drennan
Publikováno v:
MedEdPORTAL, Vol 6 (2010)
Abstract This resource features 15 brief in-class examples for general chemistry lectures that relate chemical principles to inspiring topics in biology and medicine. Running between 2 to 5 minutes each, the examples are short enough to incorporate i
Externí odkaz:
https://doaj.org/article/166fdcaa8e6c470e861faa407521e02f
Autor:
Deyu Li, James C. Delaney, Charlotte M. Page, Alvin S. Chen, Cintyu Wong, Catherine L. Drennan, John M. Essigmann
Publikováno v:
Journal of Nucleic Acids, Vol 2010 (2010)
DNA alkylation can cause mutations, epigenetic changes, and even cell death. All living organisms have evolved enzymatic and non-enzymatic strategies for repairing such alkylation damage. AlkB, one of the Escherichia coli adaptive response proteins,
Externí odkaz:
https://doaj.org/article/72c0ce95c6494c019c622d58039844e0