Zobrazeno 1 - 10
of 42
pro vyhledávání: '"Catherine K.L. Too"'
Autor:
David M. Waisman, Rong-Zong Liu, Paola Marcato, Lynn Thomas, Roseline Godbout, Penelope J. Barnes, Patricia Colp, Paola A. Marignani, Alamelu G. Bharadwaj, Catherine K.L. Too, Ryan W. Holloway, Margaret L. Dahn
Publikováno v:
Cancers, Vol 12, Iss 3673, p 3673 (2020)
Cancers
Volume 12
Issue 12
Cancers
Volume 12
Issue 12
S100A10 (p11) is a plasminogen receptor that regulates cellular plasmin generation by cancer cells. In the current study, we used the MMTV-PyMT mouse breast cancer model, patient tumor microarray, and immunohistochemical (IHC) analysis to investigate
Publikováno v:
Breast cancer research and treatment. 164(1)
Carboxypeptidase-D (CPD) cleaves C-terminal arginine (Arg) to produce nitric oxide (NO). Upregulation of CPD and NO by 17β-estradiol, prolactin (PRL), and androgen increases survival of human breast cancer (BCa) cells in vitro. To demonstrate simila
Publikováno v:
Molecular Endocrinology. 28:331-343
Plasma membrane-bound carboxypeptidase-D (CPD) cleaves C-terminal arginine from extracellular substrates. In the cell, arginine is converted to nitric oxide (NO). We have reported that up-regulation of CPD mRNA/protein levels by 17β-estradiol and pr
Autor:
Catherine K.L. Too, David Bell, Jennifer Merrimen, Vincent Goffin, Ricardo A. Rendon, Lynn Thomas
Publikováno v:
The Prostate. 74:732-742
BACKGROUND Carboxypeptidase-D (CPD) cleaves C-terminal arginine for nitric oxide (NO) production. CPD and NO levels are upregulated by testosterone (T) and prolactin (PRL) to promote survival of prostate cancer (pCa) cells. This study evaluated CPD i
Publikováno v:
Molecular and Cellular Endocrinology. 382:254-261
Mammalian α4 phosphoprotein binds to the protein phosphatase 2A catalytic subunit (PP2Ac) to regulate PP2A activity, and to poly(A)-binding protein (PABP) and progestin-inducible EDD E3 ubiquitin ligase. This study showed induction of the EDD protei
Publikováno v:
L-Arginine in Clinical Nutrition ISBN: 9783319260075
l-Arginine is an essential amino acid that plays a critical role in the growth of breast cancer cells. l-Arginine may be derived intracellularly through biosynthesis or extracellularly from diverse sources such as the culture medium in vitro, the die
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5e3bc0ce12e2f6195f3f8f876565978d
https://doi.org/10.1007/978-3-319-26009-9_20
https://doi.org/10.1007/978-3-319-26009-9_20
Autor:
Lori D. Moffat, Michelle J. Henderson, Shirley M. Sangster, William J. McDonald, Catherine K.L. Too
Publikováno v:
Journal of Cellular Biochemistry. 110:1123-1129
Mammalian alpha4 phosphoprotein, the homolog of yeast Tap42, is a component of the mammalian target-of-rapamycin (mTOR) pathway that regulates ribogenesis, the initiation of translation, and cell-cycle progression. alpha4 is known to interact with th
Publikováno v:
The Prostate. 69:595-602
INTRODUCTION Conversion of testosterone to dihydrotestosterone (DHT) by the enzymes 5α-reductase types 1 (5αR1) and 2 (5αR2) is important for normal and pathological growth of the prostate. The predominant isoenzyme in normal prostate is 5αR2. Ho
Publikováno v:
Endocrinology. 149:4821-4828
Carboxypeptidase-D (CPD) and carboxypeptidase-M (CPM) release C-terminal arginine (Arg) from polypeptides, and both are present in the plasma membrane. Cell-surface CPD increases intracellular Arg, which is converted to nitric oxide (NO). We have rep
Publikováno v:
Molecular and Cellular Endocrinology. 263:10-17
Alpha4 phosphoprotein in the mTOR pathway is a prolactin (PRL)-downregulated gene product that interacts with the catalytic subunit of serine/threonine protein phosphatase 2A (PP2Ac) in rat Nb2 lymphoma cells. Transient overexpression of alpha4 in CO