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Autor:
Matthew J. Wleklinski, James A. Thomson, Evan A. Heiderscheit, Aseem Z. Ansari, James R. Dutton, Anna S. Kropornicka, Devesh Bhimsaria, Catherine K. Vu, Mackenzie C. Spurgat, Scott Swanson, Timothy J. Kamp, Ron Stewart, Asuka Eguchi, Igor I. Slukvin, Parameswaran Ramanathan
Publikováno v:
Proceedings of the National Academy of Sciences. 113
Artificial transcription factors (ATFs) are precision-tailored molecules designed to bind DNA and regulate transcription in a preprogrammed manner. Libraries of ATFs enable the high-throughput screening of gene networks that trigger cell fate decisio