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pro vyhledávání: '"Catherine Jackson-Friedman"'
Autor:
Panya S. Manoonkitiwongsa, Robert L. Schultz, Patrick D. Lyden, Catherine Jackson-Friedman, Paul J. McMillan
Publikováno v:
Journal of Cerebral Blood Flow & Metabolism. 21:1223-1231
Brain cells manufacture and secrete angiogenic peptides after focal cerebral ischemia, but the purpose of this angiogenic response is unknown. Because the maximum possible regional cerebral blood flow is determined by the quantity of microvessels in
Publikováno v:
Journal of Stroke and Cerebrovascular Diseases. 10:99-105
Recent studies have shown that nefiracetam ameliorates cognitive dysfunction because of ischemia when behavioral testing occurs during treatment. We sought to determine if there was a persistent effect after treatment, by testing spatial learning of
Publikováno v:
Experimental Neurology. 163:477-489
We sought to prolong the window for stroke treatment using synergistic combinatorial therapy. We used the intraluminal filament occlusion model in rats to cause focal cerebral ischemia and a quantal bioassay to measure efficacy. The GABA agonist musc
Publikováno v:
Stroke. 28:387-391
Background and Purpose No therapy has been rigorously proven effective for intracerebral hematoma, although surgery is frequently used for some types of lobar hemorrhages. Since intracerebral mass causes significant ischemia in surrounding brain, we
Autor:
Catherine Jackson-Friedman, Patrick D. Lyden, Robert L. Schultz, Paul J. McMillan, Panya S. Manoonkitiwongsa
Publikováno v:
Brain research. Brain research protocols. 8(1)
Previous methods for determining morphological features of vascular networks in cerebral cortex were subject to arbitrary variation and bias. Unbiased estimates of vessel number, volume, surface area and length can be obtained using stereology but th
Publikováno v:
Experimental neurology. 147(2)
Agonists of the GABA-A receptor are neuroprotective after experimental stroke, but studies of GABA-B agonists have contradicted each other. To further investigate whether GABA-B agonists may be neuroprotective, we devised a quantal bioassay using the