Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Catherine J. Sanders"'
Autor:
Resha Bajracharya, Adrienne G. Randolph, Xiaoqing Liu, Zifeng Yang, Clifford S. Guy, Yunceng Weng, Wenda Guan, Nanshan Zhong, Thomas N. Wight, Peter Vogel, Catherine J. Sanders, Nicholas Wohlgemuth, Stacey Schultz-Cherry, David F. Boyd, Richard E. Rothman, Andrew Pekosz, Richard J. Webby, Peter M. Mourani, Xi-zhi J. Guo, Tanya Novak, Yimin Li, Jeremy Chase Crawford, Margaret M Newhams, Paul G. Thomas, Kuan-Fu Chen, Stephania A. Cormier, Thomas P. Fabrizio, E. Kaitlynn Allen, Natalie K. Lee, Kathryn Shaw-Saliba
Publikováno v:
Nature
Severe respiratory infections can result in acute respiratory distress syndrome (ARDS)1. There are no effective pharmacological therapies that have been shown to improve outcomes for patients with ARDS. Although the host inflammatory response limits
Autor:
Susu Duan, Victoria A Meliopoulos, Jennifer L McClaren, Xi-Zhi J Guo, Catherine J Sanders, Heather S Smallwood, Richard J Webby, Stacey L Schultz-Cherry, Peter C Doherty, Paul G Thomas
Publikováno v:
PLoS Pathogens, Vol 11, Iss 2, p e1004642 (2015)
The recent emergence of a novel H7N9 influenza A virus (IAV) causing severe human infections in China raises concerns about a possible pandemic. The lack of pre-existing neutralizing antibodies in the broader population highlights the potential prote
Externí odkaz:
https://doaj.org/article/5588ffd71821403d9c3f2a7168f990b7
Autor:
Peter S Askovich, Catherine J Sanders, Carrie M Rosenberger, Alan H Diercks, Pradyot Dash, Garnet Navarro, Peter Vogel, Peter C Doherty, Paul G Thomas, Alan Aderem
Publikováno v:
PLoS ONE, Vol 8, Iss 9, p e74863 (2013)
Influenza viruses exhibit large, strain-dependent differences in pathogenicity in mammalian hosts. Although the characteristics of severe disease, including uncontrolled viral replication, infection of the lower airway, and highly inflammatory cytoki
Externí odkaz:
https://doaj.org/article/5bc740ec4e6746ab9ad663948e88c2ba
Autor:
Margaret M Newhams, Nicholas Wohlgemuth, David F. Boyd, Kuan-Fu Chen, Yimin Li, Wenda Guan, Andrew Pekosz, Jeremy Chase Crawford, Richard J. Webby, Peter M. Mourani, Natalie K. Lee, Zifeng Yang, Thomas P. Fabrizio, Kathryn Shaw-Saliba, E. Kaitlynn Allen, Yunceng Weng, Adrienne G. Randolph, Xiaoqing Liu, Catherine J. Sanders, Nanshan Zhong, Thomas N. Wight, Resha Bajracharya, Paul G. Thomas, Peter Vogel, Richard E. Rothman, Stephania A. Cormier, Clifford S. Guy, Xi-zhi J. Guo, Tanya Novak, Stacey Schultz-Cherry
Publikováno v:
Nature. 588:E5-E5
Autor:
Alan Aderem, Carrie M. Rosenberger, Bart G. Jones, Peter C. Doherty, Jennifer L. McClaren, Pradyot Dash, Garnet Navarro, Catherine J. Sanders, Alan H. Diercks, Sherri L. Surman, Rebecca L. Podyminogin, Vincent C. Tam, Julia L. Hurwitz, Shari M. Kaiser, Jhoanna G. Noonan, Peter S. Askovich, Jacques J. Peschon, Paul G. Thomas
Publikováno v:
Journal of General Virology. 95:350-362
Type I alveolar epithelial cells are a replicative niche for influenza in vivo, yet their response to infection is not fully understood. To better characterize their cellular responses, we have created an immortalized murine lung epithelial type I ce
Autor:
Paul G. Thomas, Resha Bajracharya, Peter C. Doherty, Peter Vogel, Catherine J. Sanders, Jennifer L. McClaren
Publikováno v:
American Journal of Physiology-Lung Cellular and Molecular Physiology
During influenza virus infection, it is unclear how much alveolar cell loss can be tolerated before the host succumbs to the disease. We sought to define relevant correlates of disease severity in the mouse influenza model, hypothesizing that a susce
Autor:
Andrew T. Gewirtz, Luigi Franchi, Gabriel Núñez, Catherine J. Sanders, Shizuo Akira, Felix Yarovinsky, Satoshi Uematsu
Publikováno v:
European Journal of Immunology. 39:359-371
The ability of Toll-like Receptor (TLR) agonists to promote adaptive immune responses is attributed to their ability to robustly activate innate immunity. However, it has been observed that, for adjuvants in actual use in research and vaccination, TL
Autor:
Vineet D. Menachery, Jon M. Jacobs, Laurence Josset, Anil K. Shukla, Masato Hatta, Brian D. Aevermann, Gabriele Neumann, Chengjun Li, Brett E. Pickett, Feng Yang, Peter S. Askovich, Shari M. Kaiser, Pradyot Dash, Ralph S. Baric, Sophia Jeng, Alan H. Diercks, Paul G. Thomas, Susan C. Tilton, Jason E. McDermott, Amie J. Eisfeld, Casey Long, Ji Wen, Jing Wang, Jean Chang, Maria L. Luna, Jiangning Li, Bobbie-Jo M. Webb-Robertson, Nicolas Tchitchek, Melissa M. Matzke, Sudhakar Agnihothram, Rebecca L. Podyminogin, Martin T. Ferris, Sanjeev Kumar, Richard Green, Allison L. Totura, Qibin Zhang, Jeffrey M. Weiss, Marina A. Gritsenko, Amy C. Sims, Samuel O. Purvine, Catherine J. Sanders, Hugh D. Mitchell, Yoshihiro Kawaoka, Athena A. Schepmoes, Carrie M. Rosenberger, Amy B. Ellis, Matthew E. Monroe, Sara M. Kelly, Shufang Fan, Katrina M. Waters, Michael G. Katze, Lisa E. Gralinski, Therese R. W. Clauss, Boyd Yount, Vincent C. Tam, Thomas O. Metz, Edward B. Klem, Shannon K. McWeeney, Richard D. Smith, Armand Bankhead, Robert A. Heegel, Richard H. Scheuermann, Garnet Navarro, G. Lynn Law, Pavel Sova, Alan Aderem, Meagen Bolles, Victoria S. Carter
Publikováno v:
Scientific Data
The Systems Biology for Infectious Diseases Research program was established by the U.S. National Institute of Allergy and Infectious Diseases to investigate host-pathogen interactions at a systems level. This program generated 47 transcriptomic and
Publikováno v:
Mouse Models of Innate Immunity ISBN: 9781627034807
In vivo influenza infection models are critical for understanding viral dynamics and host responses during infection. Mouse models are extremely useful for infection studies requiring a high number of test animals. The vast array of gene knockout mic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::59ca4c3f8db6dbb46e9d252c644baca9
https://doi.org/10.1007/978-1-62703-481-4_20
https://doi.org/10.1007/978-1-62703-481-4_20
Publikováno v:
The Journal of Immunology. 196:78.22-78.22
Lung tissue damage is a major contributor to morbidity and mortality following infection with influenza A virus. Tissue repair, including remodeling of the extracellular matrix (ECM), is a critical process in recovery from infection. A Disintegrin an