Výsledky vyhledávání - "Catherine J. Nicholson"

Akademický článek

Maternal nicotine exposure leads to impaired disulfide bond formation and augmented endoplasmic reticulum stress in the rat placenta.

Autor: Michael K Wong, Catherine J Nicholson, Alison C Holloway, Daniel B Hardy

Publikováno v: PLoS ONE, Vol 10, Iss 3, p e0122295 (2015)

Maternal nicotine exposure has been associated with many adverse fetal and placental outcomes. Although underlying mechanisms remain elusive, recent studies have identified that augmented endoplasmic reticulum (ER) stress is linked to placental insuf

Externí odkaz: https://doaj.org/article/dc7f12ee60124c9a94e1ddbad89f4e6a

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Fetal and neonatal exposure to nicotine leads to augmented hepatic and circulating triglycerides in adult male offspring due to increased expression of fatty acid synthase

Autor: Daniel B. Hardy, Noelle Ma, Alison C. Holloway, Michael K. Wong, Catherine J. Nicholson

Publikováno v: Toxicology and Applied Pharmacology. 275:1-11

While nicotine replacement therapy is assumed to be a safer alternative to smoking during pregnancy, the long-term consequences for the offspring remain elusive. Animal studies now suggest that maternal nicotine exposure during perinatal life leads t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5fa45195c0d35d8debad9186ab518c40
https://doi.org/10.1016/j.taap.2013.12.010

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Maternal nicotine exposure leads to impaired disulfide bond formation and augmented endoplasmic reticulum stress in the rat placenta

Autor: Catherine J. Nicholson, Alison C. Holloway, Michael K. Wong, Daniel B. Hardy

Publikováno v: PLoS ONE
PLoS ONE, Vol 10, Iss 3, p e0122295 (2015)
Physiology and Pharmacology Publications

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::21e38a7cfadecaca3d6d00706b16b7da
https://pubmed.ncbi.nlm.nih.gov/25811377

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Characterization of the adverse effects of nicotine on placental development: in vivo and in vitro studies

Autor: Nadia Alfaidy, Frederic Sergent, Aude Salomon, Jean-Jacques Feige, Vanessa Garnier, Alison C. Holloway, Mohamed Benharouga, Michael J. Soares, Catherine J. Nicholson, Sandeep Raha

Publikováno v: AJP-Endocrinology and Metabolism
AJP-Endocrinology and Metabolism, American Physiological Society, 2014, 306 (4), pp.E443-E456. ⟨10.1152/ajpendo.00478.2013⟩
AJP-Endocrinology and Metabolism, 2014, 306 (4), pp.E443-E456. ⟨10.1152/ajpendo.00478.2013⟩

In utero exposure to nicotine is associated with increased risk of numerous adverse fetal and neonatal outcomes, which suggests that it acts directly to affect placental development and the establishment of the fetomaternal circulation (FC). This stu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a535cd3bcd8797b4c34ff9601508f07
https://hal.archives-ouvertes.fr/hal-01243023

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Postnatal metabolic and reproductive consequences of fetal and neonatal exposure to the smoking cessation drug bupropion

Autor: Alison C. Holloway, Jillian R. Hyslop, Hertzel C. Gerstein, Catherine J. Nicholson, Katherine M. Morrison, Nicole E. De Long

Publikováno v: Reproductive sciences (Thousand Oaks, Calif.). 20(10)

In all, 10% to 20% of all pregnant women smoke despite intentions to quit. Smoking cessation drugs such as nicotine replacement therapy (NRT) and bupropion are recommended for pregnant women. Our observation that developmental exposure to nicotine ad

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0680df8c319bf7af9761a7d693cf976
https://pubmed.ncbi.nlm.nih.gov/23439618

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The effect of smoking cessation pharmacotherapies on pancreatic beta cell function

Autor: Catherine J. Nicholson, Amanda K. Woynillowicz, Alison C. Holloway, Sandeep Raha

The goal of our study was to evaluate whether drugs currently used for smoking cessation (i.e., nicotine replacement therapy, varenicline [a partial agonist at nicotinic acetylcholine receptors (nAChR)] and bupropion [which acts in part as a nAChR an

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b281f76d03c1f6da3836e4f9ba1cd105
https://europepmc.org/articles/PMC3620565/

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