Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Catherine J. Fricano"'
Autor:
Yuyan Cheng, Yuqin Yin, Alice Zhang, Alexander M. Bernstein, Riki Kawaguchi, Kun Gao, Kyra Potter, Hui-Ya Gilbert, Yan Ao, Jing Ou, Catherine J. Fricano-Kugler, Jeffrey L. Goldberg, Zhigang He, Clifford J. Woolf, Michael V. Sofroniew, Larry I. Benowitz, Daniel H. Geschwind
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-22 (2022)
Here the authors couple an integrative genomic analysis with substantial in vitro and in vivo experimental validation, identifying REST as a novel suppressor of a pro-regenerative gene program and CNS axon regeneration in mice.
Externí odkaz:
https://doaj.org/article/df6521e5d58e42ea8efb14302c66060b
Autor:
William B. Kinlaw, William B. Coleman, Burton L. Eisenberg, Catherine J. Fricano, Leila Chaychi, Luika A. Timmerman, Johannes V. Swinnen, Peter M. Morganelli, Vincent A. Memoli, Heather M. Froehlich, Jason R. Pettus, Wendy A. Wells, Brea C. Lipe, Alison J. Flanagan, Portia S. Lombardo, Evelien Rysman, Nancy B. Kuemmerle
Supplementary Figures 1-3, Table 1 from Lipoprotein Lipase Links Dietary Fat to Solid Tumor Cell Proliferation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6929d33ad0a836799c3868e6b04bde6e
https://doi.org/10.1158/1535-7163.22496952.v1
https://doi.org/10.1158/1535-7163.22496952.v1
Autor:
William B. Kinlaw, William B. Coleman, Burton L. Eisenberg, Catherine J. Fricano, Leila Chaychi, Luika A. Timmerman, Johannes V. Swinnen, Peter M. Morganelli, Vincent A. Memoli, Heather M. Froehlich, Jason R. Pettus, Wendy A. Wells, Brea C. Lipe, Alison J. Flanagan, Portia S. Lombardo, Evelien Rysman, Nancy B. Kuemmerle
Many types of cancer cells require a supply of fatty acids (FA) for growth and survival, and interrupting de novo FA synthesis in model systems causes potent anticancer effects. We hypothesized that, in addition to synthesis, cancer cells may obtain
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9693758c3b02e567cbc18d60a872ff17
https://doi.org/10.1158/1535-7163.c.6535440
https://doi.org/10.1158/1535-7163.c.6535440
Publikováno v:
PLoS ONE, Vol 11, Iss 1, p e0146721 (2016)
A conventional study design among medical and biological experimentalists involves collecting multiple measurements from a study subject. For example, experiments utilizing mouse models in neuroscience often involve collecting multiple neuron measure
Externí odkaz:
https://doaj.org/article/9946ccf96f684935bac4974116367380
Autor:
Catherine J Fricano, Tyrone eDeSpenza, Paul eFrazel, Meijie eLi, James eO'Malley, Gary L Westbrook, Bryan Weston Luikart
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 7 (2014)
Phosphatase and tensin homolog (Pten) catalyzes the reverse reaction of PI3K by dephosphorylating PIP3 to PIP2. This negatively regulates downstream Akt/mTOR/S6 signaling resulting in decreased cellular growth and proliferation. Co-injection of a len
Externí odkaz:
https://doaj.org/article/7eb076927d3d4321a1dc6c9f1ba1edec
Autor:
Yuyan Cheng, Yuqin Yin, Alice Zhang, Alexander M. Bernstein, Riki Kawaguchi, Kun Gao, Kyra Potter, Hui-Ya Gilbert, Yan Ao, Jing Ou, Catherine J. Fricano-Kugler, Jeffrey L. Goldberg, Zhigang He, Clifford J. Woolf, Michael V. Sofroniew, Larry I. Benowitz, Daniel H. Geschwind
Publikováno v:
Nature communications, vol 13, iss 1
The inability of neurons to regenerate long axons within the CNS is a major impediment to improving outcome after spinal cord injury, stroke, and other CNS insults. Recent advances have uncovered an intrinsic program that involves coordinate regulati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d752c340a9754603b7a5f4dff6d42934
https://pubmed.ncbi.nlm.nih.gov/35906210
https://pubmed.ncbi.nlm.nih.gov/35906210
Autor:
Clifford J. Woolf, Alexander M. Bernstein, Kun Gao, Jing Ou, Larry I. Benowitz, Alice Zhang, Jeffrey L. Goldberg, Riki Kawaguchi, Hui-ya Gilbert, Yuyan Cheng, Michael V. Sofroniew, Catherine J. Fricano-Kugler, Yan Ao, Daniel H. Geschwind, Kyra Potter, Yuqin Yin
The inability of neurons to regenerate long axons within the CNS is a major impediment to improving outcome after spinal cord injury, stroke, and other CNS insults. Recent advances have uncovered an intrinsic program that involves coordinate regulati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a86b585520265ac2a60d2e26264e0a9e
https://doi.org/10.21203/rs.3.rs-102518/v1
https://doi.org/10.21203/rs.3.rs-102518/v1
Autor:
Michael R. Williams, Stephanie A. Getz, Erika L. Moen, Bryan W. Luikart, Tyrone DeSpenza, Paul W. Frazel, Alistair J. O'Malley, Catherine J. Fricano-Kugler, Ashley A. Zurawel, Meijie Li
Publikováno v:
Biol Psychiatry
Background Phosphatase and tensin homolog (PTEN) negatively regulates downstream protein kinase B signaling, resulting in decreased cellular growth and proliferation. PTEN is mutated in a subset of children with autism spectrum disorder (ASD); howeve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b3ca8593a13bbeeff503e53270a4e057
https://doi.org/10.1016/j.biopsych.2017.11.025
https://doi.org/10.1016/j.biopsych.2017.11.025
Autor:
Julia R. Salinaro, Catherine J. Fricano-Kugler, Bryan W. Luikart, Meijie Li, Michael R. Williams
Publikováno v:
Journal of Visualized Experiments : JoVE
Replication defective lentiviruses or retroviruses are capable of stably integrating transgenes into the genome of an infected host cell. This technique has been widely used to encode fluorescent proteins, opto- or chemo-genetic controllers of cell a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42e4f5c559b0e5d9ec3fd633e880d4e4
https://doi.org/10.3791/53783-v
https://doi.org/10.3791/53783-v
Autor:
Christian P. Rizzuto, Stephanie A. Getz, Catherine J. Fricano-Kugler, Joseph S. Geller, Patrick D. Skelton, Bryan W. Luikart, Michael R. Williams, Meijie Li, Jeonghoon Lee
Publikováno v:
Scientific Reports
Retroviruses expressing a fluorescent protein, Cas9 and a small guide RNA are used to mimic nonsense PTEN mutations from autism patients in developing mouse neurons. We compare the cellular phenotype elicited by CRISPR-Cas9 to those elicited using sh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e6865c6dca8c399479458c1330585b8
http://europepmc.org/articles/PMC4861960
http://europepmc.org/articles/PMC4861960