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pro vyhledávání: '"Catherine J. Derry"'
Constraints on the Efficacy of Mucosal Tolerance in Treatment of Human and Animal Arthritic Diseases
Autor:
Norman A. Staines, Lilia Marinova‐Mutafchieva, John J. Murphy, Catherine J. Derry, D. Huw Davies, Nadira Ali
Publikováno v:
Annals of the New York Academy of Sciences. 1029:250-259
Mucosal administration of an autoantigen has been shown to be a powerful way of inducing tolerance in both animal and human arthritis clinical trials. Bovine or chicken type II collagen has been administered orally to rheumatoid arthritis patients, r
Publikováno v:
Arthritis & Rheumatism. 44:1917-1927
Objective To determine the influence of the dose of collagen given nasally on the induction of specific mucosal tolerance in collagen-induced arthritis. Methods The severity of clinical arthritis induced in DBA/1 mice was studied after the nasal admi
Publikováno v:
European Journal of Immunology. 29:419-430
The migration of lymphocytes into lymph nodes via high endothelial venules (HEV) is dependent on the expression of L-selectin on the lymphocyte cell surface. HEV express several L-selectin ligands including CD34, GlyCAM-1, MAdCAM-1 and two sulfated g
Publikováno v:
Biochemical Society transactions. 25(2)