Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Catherine J Yeates"'
Autor:
Douglas J Brusich, Ashlyn M Spring, Thomas D James, Catherine J Yeates, Timothy H Helms, C Andrew Frank
Publikováno v:
PLoS Genetics, Vol 14, Iss 8, p e1007577 (2018)
Gain-of-function mutations in the human CaV2.1 gene CACNA1A cause familial hemiplegic migraine type 1 (FHM1). To characterize cellular problems potentially triggered by CaV2.1 gains of function, we engineered mutations encoding FHM1 amino-acid substi
Externí odkaz:
https://doaj.org/article/8e84afdcc7674cc9a7d61507fc3ce816
Autor:
Catherine J. Yeates, C. Andrew Frank
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 15 (2021)
Synapses and circuits rely on homeostatic forms of regulation in order to transmit meaningful information. The Drosophila melanogaster neuromuscular junction (NMJ) is a well-studied synapse that shows robust homeostatic control of function. Most prio
Externí odkaz:
https://doaj.org/article/7211046b49a546e3b9365c6636b093ee
Publikováno v:
iScience, Vol 23, Iss 12, Pp 101823- (2020)
Summary: To understand the progression of Alzheimer's disease, studies often rely on ectopic expression of amyloid-beta 42 (Aβ42) throughout an entire tissue. Uniform ectopic expression of Aβ42 may obscure cell-cell interactions that contribute to
Externí odkaz:
https://doaj.org/article/d01fb0cf2d6a41289816f9b1fbb2ba2f
Publikováno v:
iScience
iScience, Vol 23, Iss 12, Pp 101823-(2020)
iScience, Vol 23, Iss 12, Pp 101823-(2020)
Summary To understand the progression of Alzheimer's disease, studies often rely on ectopic expression of amyloid-beta 42 (Aβ42) throughout an entire tissue. Uniform ectopic expression of Aβ42 may obscure cell-cell interactions that contribute to t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df3daa112be8013a29c31cef041d8fce
https://pubmed.ncbi.nlm.nih.gov/33319169
https://pubmed.ncbi.nlm.nih.gov/33319169
Publikováno v:
Insights into Human Neurodegeneration: Lessons Learnt from Drosophila ISBN: 9789811322174
Alzheimer’s disease (AD) is a debilitating neurodegenerative disorder that predominantly affects people aged over 65 years. AD is marked by cognitive deficits and memory problems that worsen with age and ultimately results in death. Pathology of AD
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7cf6180bcb3db578252f0954d47dfb9f
https://doi.org/10.1007/978-981-13-2218-1_9
https://doi.org/10.1007/978-981-13-2218-1_9
Autor:
C. Andrew Frank, Catherine J. Yeates
Homeostasis is a vital mode of biological self-regulation. The hallmarks of homeostasis for any biological system are a baseline set point of physiological activity, detection of unacceptable deviations from the set point, and effective corrective me
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d4ce46592999ef58414bdf3d5d09d45
https://doi.org/10.1101/154930
https://doi.org/10.1101/154930
Autor:
Douglas J Brusich, Thomas D. James, Ashlyn M. Spring, Timothy H. Helms, C. Andrew Frank, Catherine J. Yeates
Gain-of-function mutations in the human CaV2.1 gene CACNA1A cause familial hemiplegic migraine type 1 (FHM1). To characterize cellular problems potentially triggered by CaV2.1 gains of function, we engineered mutations encoding FHM1 amino-acid substi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::afa289e63554deee5d9ba76c598891a6
https://doi.org/10.1101/141366
https://doi.org/10.1101/141366
Autor:
C. Andrew Frank, Ashlyn M. Spring, Douglas J. Brusich, Timothy H. Helms, Thomas D. James, Catherine J. Yeates
Publikováno v:
PLoS Genetics
PLoS Genetics, Vol 14, Iss 8, p e1007577 (2018)
PLoS Genetics, Vol 14, Iss 8, p e1007577 (2018)
Gain-of-function mutations in the human CaV2.1 gene CACNA1A cause familial hemiplegic migraine type 1 (FHM1). To characterize cellular problems potentially triggered by CaV2.1 gains of function, we engineered mutations encoding FHM1 amino-acid substi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9927de23c394e9c5fcc523b87ea75189
https://doi.org/10.1371/journal.pgen.1007577
https://doi.org/10.1371/journal.pgen.1007577
Publikováno v:
eNeuro
Homeostasis is a vital mode of biological self-regulation. The hallmarks of homeostasis for any biological system are a baseline set point of physiological activity, detection of unacceptable deviations from the set point, and effective corrective me
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f7a4a597371671517360ede2f76d07c
https://doi.org/10.1523/eneuro.0220-17.2017
https://doi.org/10.1523/eneuro.0220-17.2017