Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Catherine J Leader"'
Autor:
Catherine J Leader, Mohammed Moharram, Sean Coffey, Ivan A Sammut, Gerard W Wilkins, Robert J Walker
Publikováno v:
PLoS ONE, Vol 14, Iss 8, p e0220837 (2019)
ObjectivesIs global longitudinal strain (GLS) a more accurate non-invasive measure of histological myocardial fibrosis than left ventricular ejection fraction (LVEF) in a hypertensive rodent model.BackgroundHypertension results in left ventricular hy
Externí odkaz:
https://doaj.org/article/5c4924df9e5e434d91d1d3c8858a3451
Publikováno v:
Physiological Reports, Vol 8, Iss 10, Pp n/a-n/a (2020)
Abstract Hypertension plays an important role in the development and progression of chronic kidney disease. Studies to date, with mineralocorticoid receptor antagonists (MRA), have demonstrated varying degrees of results in modifying the development
Externí odkaz:
https://doaj.org/article/7b538cbd83e446bca62cbd2a518b13c5
Publikováno v:
PLoS ONE, Vol 16, Iss 11, p e0260554 (2021)
PLoS ONE
PLoS ONE
Aims The renin-angiotensin-aldosterone axis plays a key role in mediating cardiac and kidney injury. Mineralocorticoid receptor antagonism has beneficial effects on cardiac dysfunction, but effects are less well quantified in the cardiorenal syndrome
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::acc672e11ac7417802214da6e85efe67
https://doaj.org/article/e5620ebd6db5467d8437982c2cebdc72
https://doaj.org/article/e5620ebd6db5467d8437982c2cebdc72
Publikováno v:
Physiological Reports, Vol 8, Iss 10, Pp n/a-n/a (2020)
Physiological Reports
Physiological Reports
Hypertension plays an important role in the development and progression of chronic kidney disease. Studies to date, with mineralocorticoid receptor antagonists (MRA), have demonstrated varying degrees of results in modifying the development of renal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::81d34e0d11a2c62afd8bfadbc194b213
https://doaj.org/article/7b538cbd83e446bca62cbd2a518b13c5
https://doaj.org/article/7b538cbd83e446bca62cbd2a518b13c5
Autor:
Fiona J. McDonald, Ivan A. Sammut, Sama Mugloo, Robert J. Walker, Martin Fronius, Andrew Bahn, Zoe Ashley, Catherine J Leader
Publikováno v:
The FASEB Journal. 32
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::166080e61fecd5fdc3e2a93a26fce64a
https://doi.org/10.1096/fasebj.2018.32.1_supplement.581.6
https://doi.org/10.1096/fasebj.2018.32.1_supplement.581.6
Autor:
Robert J. Walker, Hans-Peter Marti, Catherine J Leader, Andreas Scherer, Jennifer J. Bedford, Aaron Jeffs, John P. Leader
Publikováno v:
PLoS ONE
PLoS ONE, Vol 11, Iss 12, p e0168240 (2016)
PLoS ONE, Vol 11, Iss 12, p e0168240 (2016)
Accurate diagnosis of fibrosis is of paramount clinical importance. A human fibrosis classifier based on metzincins and related genes (MARGS) was described previously. In this investigation, expression changes of MARGS genes were explored and evaluat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bbfdf0b79750b42aa64d6c02f52d2826
https://pubmed.ncbi.nlm.nih.gov/28002484
https://pubmed.ncbi.nlm.nih.gov/28002484