Zobrazeno 1 - 10
of 98
pro vyhledávání: '"Catherine H Botting"'
Autor:
Heidi R Fuller, Berhan eMandefro, Sally L Shirran, Andrew R Gross, Anjoscha Samija Kaus, Catherine H Botting, Glenn E Morris, Dhruv eSareen
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 9 (2016)
Spinal muscular atrophy (SMA) is an inherited neuromuscular disease primarily characterized by degeneration of spinal motor neurons, and caused by reduced levels of the SMN protein. Previous studies to understand the proteomic consequences of reduced
Externí odkaz:
https://doaj.org/article/df5a2412124f4abbb23296861b2a14bc
Autor:
Miriam Walden, John M Edwards, Aleksandra M Dziewulska, Rene Bergmann, Gerhard Saalbach, Su-Yin Kan, Ona K Miller, Miriam Weckener, Rosemary J Jackson, Sally L Shirran, Catherine H Botting, Gordon J Florence, Manfred Rohde, Mark J Banfield, Ulrich Schwarz-Linek
Publikováno v:
eLife, Vol 4 (2015)
To cause disease and persist in a host, pathogenic and commensal microbes must adhere to tissues. Colonization and infection depend on specific molecular interactions at the host-microbe interface that involve microbial surface proteins, or adhesins.
Externí odkaz:
https://doaj.org/article/0ac783f109244594ad7361157650fd3d
Autor:
Robert S Illingworth, Catherine H Botting, Graeme R Grimes, Wendy A Bickmore, Ragnhild Eskeland
Publikováno v:
PLoS ONE, Vol 7, Iss 4, p e34848 (2012)
The essential histone variant H2A.Z localises to both active and silent chromatin sites. In embryonic stem cells (ESCs), H2A.Z is also reported to co-localise with polycomb repressive complex 2 (PRC2) at developmentally silenced genes. The mechanism
Externí odkaz:
https://doaj.org/article/44b36230600343708583252199f81c68
Autor:
Johannes Beiersdorf, Zsofia Hevesi, Daniela Calvigioni, Jakob Pyszkowski, Roman Romanov, Edit Szodorai, Gert Lubec, Sally Shirran, Catherine H. Botting, Siegfried Kasper, Geoffrey W. Guy, Roy Gray, Vincenzo Di Marzo, Tibor Harkany, Erik Keimpema
Publikováno v:
JCI Insight, Vol 5, Iss 23 (2020)
Ongoing societal changes in views on the medical and recreational roles of cannabis increased the use of concentrated plant extracts with a Δ9-tetrahydrocannabinol (THC) content of more than 90%. Even though prenatal THC exposure is widely considere
Externí odkaz:
https://doaj.org/article/ee601afc4d3f4d30959f316aeb3e946f
Autor:
Jianhong Yang, Yuxi Wang, Taijing Wang, Jian Jiang, Catherine H. Botting, Huanting Liu, Qiang Chen, Jinliang Yang, James H. Naismith, Xiaofeng Zhu, Lijuan Chen
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-9 (2016)
Microtubule assembly and disassembly is the target of many anticancer therapies, with β-tubulin the most-frequent target. Here, the authors used biochemical and biophysical techniques to demonstrate pironetin binds to α-tubulin and thereby inhibits
Externí odkaz:
https://doaj.org/article/706d09f37b2b4e7daab3ae36d7438e61
Autor:
Swati Arya, Dagmara Wiatrek-Moumoulidis, Silvia A. Synowsky, Sally L. Shirran, Catherine H. Botting, Simon J. Powis, Alan J. Stewart
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-11 (2019)
Dendritic cells are key immune cells that respond to pathogens and co-ordinate many innate and adaptive immune responses. Quantitative mass spectrometry using Sequential Window Acquisition of all THeoretical fragment-ion spectra-Mass Spectrometry (SW
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doajarticles::11be156adfef81345ebbe0117fc49789
http://link.springer.com/article/10.1038/s41598-019-40773-6
http://link.springer.com/article/10.1038/s41598-019-40773-6
Autor:
Sally L. Shirran, Karina T. Wright, Heidi R. Fuller, Catherine H. Botting, Aheed Osman, Charlotte H Hulme, John S. Riddell
Publikováno v:
Spinal cord. 60(4)
Study designExplanatory and mechanistic study.ObjectivesA better understanding of the ‘whole-body’ response following spinal cord injury (SCI) is needed to guide future research aimed at developing novel therapeutic interventions and identifying
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb792b8de8d6ef49e28166bbd6d4661e
https://pubmed.ncbi.nlm.nih.gov/34601498
https://pubmed.ncbi.nlm.nih.gov/34601498
Autor:
Valentina Cinquina, Florian Halbritter, Ken Mackie, Sally L. Shirran, Matthias Farlik, Fabinan Piscitelli, Vincenzo Di Marzo, Patrick Poullet, Chris J. McBain, Zoltán Máté, Daniela Calvigioni, Christoph Bock, Matthew Fuszard, Yuchio Yanagawa, Siegfried Kasper, Victoria Fife-Gernedl, Gábor Szabó, Catherine H. Botting, Erik Keimpema, Tibor Harkany
Publikováno v:
Molecular Psychiatry
Molecular psychiatry (2019). doi:10.1038/s41380-019-0580-4
info:cnr-pdr/source/autori:Cinquina V.; Calvigioni D.; Farlik M.; Halbritter F.; Fife-Gernedl V.; Shirran S.L.; Fuszard M.A.; Botting C.H.; Poullet P.; Piscitelli F.; Mate Z.; Szabo G.; Yanagawa Y.; Kasper S.; Di Marzo V.; Mackie K.; McBain C.J.; Bock C.; Keimpema E.; Harkany T./titolo:Life-long epigenetic programming of cortical architecture by maternal 'Western' diet during pregnancy/doi:10.1038%2Fs41380-019-0580-4/rivista:Molecular psychiatry/anno:2019/pagina_da:/pagina_a:/intervallo_pagine:/volume
Molecular psychiatry (2019). doi:10.1038/s41380-019-0580-4
info:cnr-pdr/source/autori:Cinquina V.; Calvigioni D.; Farlik M.; Halbritter F.; Fife-Gernedl V.; Shirran S.L.; Fuszard M.A.; Botting C.H.; Poullet P.; Piscitelli F.; Mate Z.; Szabo G.; Yanagawa Y.; Kasper S.; Di Marzo V.; Mackie K.; McBain C.J.; Bock C.; Keimpema E.; Harkany T./titolo:Life-long epigenetic programming of cortical architecture by maternal 'Western' diet during pregnancy/doi:10.1038%2Fs41380-019-0580-4/rivista:Molecular psychiatry/anno:2019/pagina_da:/pagina_a:/intervallo_pagine:/volume
Funding: European Research Council (SECRET-CELLS, ERC-2015-AdG-695136; T.H.); Wellcome Trust grant number 094476/Z/10/Z, which funded the purchase of the TripleTOF 5600 mass spectrometer at the BSRC Mass Spectrometry and Proteomics Facility, Universi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd6d72c6b97eeebef5c045a1df9e656f
Publikováno v:
Archaea, Vol 2010 (2010)
In eukarya and bacteria, lysine methylation is relatively rare and is catalysed by sequence-specific lysine methyltransferases that typically have only a single-protein target. Using RNA polymerase purified from the thermophilic crenarchaeum Sulfolob
Externí odkaz:
https://doaj.org/article/a66d3597ba434dbba603b6303e2d704b
Autor:
Catherine H. Botting, Adolfo García-Sastre, Corinna Patzina, Richard E. Randall, Benjamin G. Hale
Publikováno v:
The Journal of General Virology
This work was partially supported by NIAID grant U19AI106754, and by CRIP (Center for Research in Influenza Pathogenesis), an NIAID funded Center of Excellence for Influenza Research and Surveillance (CEIRS, contract #HHSN272201400008C) to A. G-S. Wo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce431e17fc0edadd63eb842295543ce9
https://doi.org/10.1099/jgv.0.000909
https://doi.org/10.1099/jgv.0.000909