Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Catherine Grande"'
Autor:
Tanios S. Bekaii Saab, Renuka Iyer, Venkata K. Pokuri, Catherine Grande, Dan Iancu, Adrienne Groman, Wen Wee Ma, Usha Malhotra
Publikováno v:
American Journal of Clinical Oncology. 41:649-655
Objectives Vascular endothelial growth factor overexpression, seen in 42% to 76% of biliary tract cancers (BTCs), correlates with poor survival. We explored the safety/efficacy and potential biomarkers for bevacizumab in combination with gemcitabine-
Autor:
Venkata K. Pokuri, Gerald J. Fetterly, Catherine Grande, Edward Ashton, Sihem Ait-Oudhia, Garin Tomaszewski, Nikhil I. Khushalani, Adrienne Groman, Amit A. Lugade, Renuka Iyer, Yasmin Thanavala
Publikováno v:
American journal of clinical oncology. 41(4)
To evaluate the safety/efficacy and explore biomarkers for a rationally designed combination of sunitinib and transarterial chemoembolization (TACE) in a prospective phase 2 study of advanced hepatocellular carcinoma (HCC). Inoperable HCC patients wi
Autor:
Geoffrey Catalano, Michelle A. Romano, Carleton C. Stewart, Frank Santaniello, Nicholas W. Keiser, Thomas B. Tomasi, William J. Magner, Catherine Grande, A. Latif Kazim
Publikováno v:
The Journal of Immunology. 165:7017-7024
Epigenetic mechanisms are involved in regulating chromatin structure and gene expression through repression. In this study, we show that histone deacetylase inhibitors (DAIs) that alter the acetylation of histones in chromatin enhance the expression
Publikováno v:
Journal of Reproductive Immunology. 32:125-144
Previous work from this laboratory has shown that transforming growth factor beta 2 (TGF-beta 2) mRNA is abundant in the pregnant uterus. In the present study, we examined the synthesis and secretion of TGF-beta 1,2 and 3 in the rat uterus and mammar
Publikováno v:
Journal of Interferon & Cytokine Research. 15:485-491
The initiation of the immune response is regulated, in part, by the effect of cytokines on the level of expression of major histocompatibility complex (MHC) class II antigens on antigen-presenting cells (APC). The expression of class II antigens on B
Autor:
Hwei-Ling Cheng, Colleen M. Kane, Thomas B. Tomasi, Diane Thompson, Sara L. Schneider, Eugenia Pietrzak, Sandra O. Gollnick, Catherine Grande
Publikováno v:
Journal of Reproductive Immunology. 25:133-148
The transforming growth factor beta family of peptides have diverse actions on the reproductive tracts of primates and rodents. In this study we report the expression of high levels of mRNA of one member of this superfamily, TGF-beta 2, in the pregna
Autor:
Renuka Iyer, Tanios Bekaii-Saab, Usha Malhotra, Dan Iancu, Wen Wee Ma, Adrienne Groman, Catherine Grande
Publikováno v:
Journal of Clinical Oncology. 33:4078-4078
4078 Background: Role of antiangiogenic therapy is still undefined in ABC. We examined BV combined with G + C, a standard chemotherapy for ABC when the study began. Methods: Pts with ABC (inoperabl...
Autor:
Renuka V. Iyer, Garin Tomaszewski, Yuhsin V Wu, Boris W. Kuvshinoff, Adrienne E. Groman, Nikhil I. Khushalani, Catherine Grande, Patricia D. Zagst, Kimberly Clark, Gerald J. Fetterly
Publikováno v:
Journal of Clinical Oncology. 30:275-275
275 Background: TACE and anti-angiogenic agents have individually been effective in inoperable HCC. In this prospective phase 2 study, the effects and PFS of Su+TACE was evaluated. Methods: Eligibility: ECOG PS 0, 1, inoperable HCC, Child Pugh (CP) A