Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Catherine Gaulon"'
Autor:
Florian Rouzier, Ophélie Montiège, Jérôme Lhoste, Catherine Gaulon-Nourry, Anne-Sophie Castanet, Anne-Caroline Chany
Publikováno v:
The Journal of Organic Chemistry. 87:14264-14273
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b4640ff73baadddf36fbe92c46e55767
https://doi.org/10.1021/acs.joc.2c01762
https://doi.org/10.1021/acs.joc.2c01762
Autor:
Arnaud Martel, Bohdan Biletskyi, Catherine Gaulon-Nourry, Imen Abid, Sylvain Henrion, Gilles Dujardin, Annie Hémon-Ribaud, Jérôme Lhoste, Sigrid Gavelle
Publikováno v:
The Journal of Organic Chemistry. 86:4917-4931
Aldol addition of α-triisopropylsilyl-α-diazoacetone (TIPS-diazoacetone), promoted by excess lithium diisopropylamide (LDA), was developed and applied to the synthesis of original C-TIPS diazoaldols, C-TIPS diazoketols, and a related Mannich-type p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d830f5ae1f5ef44fe1bb614819b47003
https://doi.org/10.1021/acs.joc.0c02725
https://doi.org/10.1021/acs.joc.0c02725
Publikováno v:
P. Andrew Evans. Wiley, 101, pp.1-550, 2020, Organic Reactions, ⟨10.1002/0471264180.or101.01⟩
Organic Reactions
Organic Reactions
International audience; 3,4‐Dihydro‐2H‐pyrans are present in the skeletons of several natural products, and these versatile synthetic intermediates are readily transformed into tetrahydropyrans, pyridines, or 1,5‐dicarbonyl units. Among the s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fcbaf4c8f0929afe5067fa0ddc6e4253
https://hal.archives-ouvertes.fr/hal-02468277
https://hal.archives-ouvertes.fr/hal-02468277
Advances in the TBAF-induced aldol-type addition of α-trialkylsilyl-α-diazoacetones: TIPS versus TES
Autor:
Sigrid Gavelle, Catherine Gaulon-Nourry, Frédéric Legros, Souhir Abid, Imen Abid, Pascal Gosselin, Gilles Dujardin, Anne-Caroline Chany
Publikováno v:
Comptes Rendus Chimie. 20:595-600
α-Triisopropylsilyl-α-diazoacetone (TIPS-diazoacetone) underwent high-yielding “diazo-side” Mukaiyama aldol-type addition with a range of aryl and alkyl aldehydes when subjected to stoichiometric amount of tetrabutylammonium fluoride at −16
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::755e4aba5521f8a7e0758243ae61f8a6
https://doi.org/10.1016/j.crci.2016.12.005
https://doi.org/10.1016/j.crci.2016.12.005
Autor:
Uday Kumar Kundu, Heloua Haroun, Bertrand Carboni, Aurélie Macé, Catherine Gaulon-Nourry, Pascal Gosselin, Sergii Torlak, Frédéric Legros, Bohdan Biletskyi, Brigitte Renoux, Gilles Dujardin, Monique Mathé-Allainmat, Jacques Lebreton, Anne-Caroline Chany
Publikováno v:
Organic Letters
Organic Letters, American Chemical Society, 2019, 21 (9), pp.2988-2992. ⟨10.1021/acs.orglett.9b00413⟩
Organic Letters, 2019, 21 (9), pp.2988-2992. ⟨10.1021/acs.orglett.9b00413⟩
Organic Letters, American Chemical Society, 2019, 21 (9), pp.2988-2992. ⟨10.1021/acs.orglett.9b00413⟩
Organic Letters, 2019, 21 (9), pp.2988-2992. ⟨10.1021/acs.orglett.9b00413⟩
International audience; A convergent and rapid synthesis of original C2,C3-unsaturated, C11,C13-keto-enol macrocycles with a peloruside A skeleton has been developed. These original unsaturated macrocycles constitute valuable platforms to access pelo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b1181c3dce63ca7e04af06bc66beea1
https://pubmed.ncbi.nlm.nih.gov/30859834
https://pubmed.ncbi.nlm.nih.gov/30859834
Autor:
Khaoula Jebali, Thibaut Chalopin, Jacques Lebreton, Monique Mathé-Allainmat, Fabrice Dénès, Catherine Gaulon-Nourry
Publikováno v:
Tetrahedron
Tetrahedron, Elsevier, 2016, 72 (2), pp.318-327. ⟨10.1016/j.tet.2015.11.046⟩
Tetrahedron, Elsevier, 2016, 72 (2), pp.318-327. ⟨10.1016/j.tet.2015.11.046⟩
The rapid and regioselective synthesis of a series of 2,6-disubstituted dihydropyranic building-blocks bearing an oxygenated side chain is described. The corresponding 4-iodo tetrahydropyran precursors, easily prepared by Prins cyclization, underwent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22e140b2f53cc2177c32b547ba0e0730
https://doi.org/10.1016/j.tet.2015.11.046
https://doi.org/10.1016/j.tet.2015.11.046
Autor:
Imen Abid, Monique Mathé-Allainmat, Gilles Dujardin, Catherine Gaulon-Nourry, Pascal Gosselin, Souhir Abid
Publikováno v:
The Journal of Organic Chemistry. 80:9980-9988
Aldol-type addition of α-triethylsilyl-α-diazoacetone was achieved under nucleophilic activation by tetrabutylammonium fluoride (TBAF). The use of a semistoichiometric amount of TBAF (protocol P1) provided the corresponding β-hydroxy-α-diazoaceto
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d29d8228fc227c3d41d7d68906553de
https://doi.org/10.1021/acs.joc.5b01554
https://doi.org/10.1021/acs.joc.5b01554
Autor:
Thibaut Chalopin, Fabrice Dénès, Monique Mathé-Allainmat, Catherine Gaulon-Nourry, Khaoula Jebali, Jacques Lebreton
Publikováno v:
ChemInform. 47
The rapid and regioselective synthesis of a series of 2,6-disubstituted dihydropyranic building-blocks bearing an oxygenated side chain is described. The corresponding 4-iodo tetrahydropyran precursors, easily prepared by Prins cyclization, underwent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::73e86d0ebf809624323a86d17a77f743
https://doi.org/10.1002/chin.201622148
https://doi.org/10.1002/chin.201622148
Autor:
Pascal Gosselin, Gilles Dujardin, Monique Mathé-Allainmat, Imen Abid, Souhir Abid, Catherine Gaulon-Nourry
Publikováno v:
ChemInform. 47
Aldol-type addition of α-triethylsilyl-α-diazoacetone was achieved under nucleophilic activation by tetrabutylammonium fluoride (TBAF). The use of a semistoichiometric amount of TBAF (protocol P1) provided the corresponding β-hydroxy-α-diazoaceto
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4a4ba11a3d83d11c132ffdb4519b6dce
https://doi.org/10.1002/chin.201609080
https://doi.org/10.1002/chin.201609080
Autor:
Florence I. Raynaud, Ion Niculescu-Duvaz, Catherine Gaulon, Douglas Hedley, Bart M. J. M. Suijkerbuijk, Caroline J. Springer, Ruth Kirk, Arnaud Nourry, Frank Friedlos, Javier Moreno-Farre, Richard Marais, Lesley Ogilvie, Dan Niculescu-Duvaz, Alfonso Zambon, Delphine Menard, Harmen P. Dijkstra, Adrian Liam Gill, Helen A. Manne, Richard D. Taylor, Lawrence Davies, Steven R. Whittaker
Publikováno v:
Journal of Medicinal Chemistry. 52:2255-2264
BRAF is a serine/threonine kinase that is mutated in a range of cancers, including 50-70% of melanomas, and has been validated as a therapeutic target. We have designed and synthesized mutant BRAF inhibitors containing pyridoimidazolone as a new hing
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ad68c3081419fe9b96e5b2d9b200efb
https://doi.org/10.1021/jm801509w
https://doi.org/10.1021/jm801509w