Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Catherine G. Triandafillou"'
Publikováno v:
PLoS Computational Biology, Vol 19, Iss 10, p e1011565 (2023)
Understanding how protein sequences confer function remains a defining challenge in molecular biology. Two approaches have yielded enormous insight yet are often pursued separately: structure-based, where sequence-encoded structures mediate function,
Externí odkaz:
https://doaj.org/article/40cc7b87a8974ed7808832dd547080a9
Publikováno v:
eLife, Vol 9 (2020)
Heat shock induces a conserved transcriptional program regulated by heat shock factor 1 (Hsf1) in eukaryotic cells. Activation of this heat shock response is triggered by heat-induced misfolding of newly synthesized polypeptides, and so has been thou
Externí odkaz:
https://doaj.org/article/97f1c9ac38f7443a8b8ae635218967bc
Publikováno v:
bioRxiv
Understanding how protein sequences confer function remains a defining challenge in molecular biology. Two approaches have yielded enormous insight yet are often pursued separately: structure-based, where sequence-encoded structures mediate function,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bee1a925c3aff7d829876c8ab35131b0
https://europepmc.org/articles/PMC9949069/
https://europepmc.org/articles/PMC9949069/
Publikováno v:
Journal of Biological Chemistry. 294:7151-7159
Phase separation creates two distinct liquid phases from a single mixed liquid phase, like oil droplets separating from water. Considerable attention has focused on how the products of phase separation-the resulting condensates-might act as biologica
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a77a495e721179b2a8b3ff84435a372d
https://doi.org/10.1074/jbc.tm118.001191
https://doi.org/10.1074/jbc.tm118.001191
Publikováno v:
eLife, Vol 9 (2020)
Heat shock induces a conserved transcriptional program regulated by heat shock factor 1 (Hsf1) in eukaryotic cells. Activation of this heat-shock response is triggered by heat-induced misfolding of newly synthesized polypeptides, and so has been thou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ee41b15d90c47bd648b9d5df25d13f3
https://doi.org/10.7554/elife.54880
https://doi.org/10.7554/elife.54880
Publikováno v:
Bio Protoc
The intracellular pH of yeast is a tightly regulated physiological cue that changes in response to growth state and environmental conditions. Fluorescent reporters, which have altered fluorescence in response to local pH changes, can be used to measu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f40ad71a4cdecab85760ebc6ea89b4a
https://europepmc.org/articles/PMC7842330/
https://europepmc.org/articles/PMC7842330/
Autor:
Wenguang G. Liang, Shiladitya Banerjee, Catherine G. Triandafillou, Wei-Jen Tang, Aaron R. Dinner, Teng-Yi Huang, Shang-Cheng Hung, Medel Manuel L. Zulueta
Publikováno v:
Proceedings of the National Academy of Sciences. 113:5000-5005
CC chemokine ligand 5 (CCL5) and CCL3 are critical for immune surveillance and inflammation. Consequently, they are linked to the pathogenesis of many inflammatory conditions and are therapeutic targets. Oligomerization and glycosaminoglycan (GAG) bi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c4b36a5a7ed6a4b18facaae242baa55
https://doi.org/10.1073/pnas.1523981113
https://doi.org/10.1073/pnas.1523981113
Publikováno v:
Molecular Cell. 63:1-2
HSF1 is the supposed master regulator of the heat shock response. In this issue of Molecular Cell, Solis et al. reveal that it has a much narrower job description: organizing a small team of molecular chaperones that keep the proteome moving.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e3995925dc2eeb7b7ffd23fd79a87b6d
https://doi.org/10.1016/j.molcel.2016.06.026
https://doi.org/10.1016/j.molcel.2016.06.026
Publikováno v:
The journal of physical chemistry. A. 117(46)
In order to investigate experimentally observed phototautomerization of gas-phase cytosine, several excited-state tautomerization mechanisms were characterized at the EOM-CCSD and TDDFT levels. All pathways that took place exclusively on the S1 surfa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fefc5b0531eb646bc301744bbf8c27b3
https://pubmed.ncbi.nlm.nih.gov/24094271
https://pubmed.ncbi.nlm.nih.gov/24094271