Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Catherine Frelin"'
Autor:
Alexandra Berger, Catherine Frelin, Divya K Shah, Patricia Benveniste, Robert Herrington, Norma P Gerard, Juan-Carlos Zúñiga-Pflücker, Norman N Iscove, Christopher J Paige
Publikováno v:
PLoS ONE, Vol 8, Iss 3, p e58787 (2013)
Tachykinins are a large group of neuropeptides with both central and peripheral activity. Despite the increasing number of studies reporting a growth supportive effect of tachykinin peptides in various in vitro stem cell systems, it remains unclear w
Externí odkaz:
https://doaj.org/article/3063c4254b5f4a399fd3e2fa3ea9502b
Autor:
Patrycja K. Thompson, Edward L. Y. Chen, Renée F. de Pooter, Catherine Frelin, Walter K. Vogel, Christina R. Lee, Thomas Venables, Divya K. Shah, Norman N. Iscove, Mark Leid, Michele K. Anderson, Juan Carlos Zúñiga-Pflücker
Publikováno v:
J Immunol
The zinc-finger transcription factor GATA-3 plays a crucial role during early T cell development and also dictates later T cell differentiation outcomes. However, its role and collaboration with the Notch signaling pathway in the induction of T linea
Autor:
Mary Barbara, Guy Sauvageau, Patricia Benveniste, Catherine Frelin, Salima Janmohamed, Juan Carlos Zúñiga-Pflücker, Deborah Hyam, Christopher J. Paige, Harvey Lim, Jana Krosl, Robert Herrington, Norman N. Iscove, Carol Stocking
As hemopoietic stem cells differentiate, their proliferative lifespan shortens by unknown mechanisms. Homeobox cluster (Hox) genes have been implicated by their enhancement of self-renewal when transduced into hemopoietic cells, but gene deletions ha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75342029e11997f9057d81f9a072b752
Autor:
Abdallah Souabni, Juan Carlos Zúñiga-Pflücker, Salima Janmohamed, Patricia Benveniste, Meinrad Busslinger, Robert Herrington, Mary Barbara, Norman N. Iscove, Catherine Frelin, Gary Tran, Christopher J. Paige
Publikováno v:
Nature immunology
The transcription factor GATA-3 is expressed and required for differentiation and function throughout the T lymphocyte lineage. Despite evidence it may also be expressed in multipotent hematopoietic stem cells (HSCs), any role for GATA-3 in these cel
Autor:
Salima Janmohamed, Norman N. Iscove, Enrique M. Muro, Robert Herrington, Catherine Frelin, Miguel A. Andrade-Navarro
Publikováno v:
Proceedings of the National Academy of Sciences. 105:20286-20290
The properties and biology of mRNA transcripts can be affected profoundly by the choice of alternative polyadenylation sites, making definition of the 3′ ends of transcripts essential for understanding their regulation. Here we show that 22–52% o
Autor:
Patrick Auberger, Virginie Bottero, Klaus Schulze-Osthoff, Véronique Imbert, N Gonthier, Catherine Frelin, Ajoy K. Samraj, J F Peyron, G Courtois
Publikováno v:
Cell Death & Differentiation. 15:152-160
Apoptosis is mediated by cysteine-dependent, aspartate-directed proteases of the caspase family that proteolyse strategic intracellular substrates to induce cell suicide. We describe here that engagement of apoptotic processes by Fas triggering or by
Autor:
Virginie Bottero, V??ronique Imbert, Catherine Frelin, Jean-Louis Formento, Jean-Fran??ois Peyron
Publikováno v:
Molecular Diagnosis. 7:187-194
Autor:
Véronique Imbert, Virginie Bottero, Patrick Auberger, Catherine Frelin, Jean-Erhland Ricci, Valère Busuttil, Jean-Francois Peyron
Publikováno v:
Oncogene. 21:3213-3224
The transcription factor NF-kappaB promotes cell survival. Using a variant of Jurkat leukemic T cells expressing IkappaB-alphaDeltaN, a super-repressor of NF-kappaB activation we first show that the tumor promoter PMA could prevent Fas-induced apopto
Autor:
Elisa, Laurenti, Catherine, Frelin, Stephanie, Xie, Robin, Ferrari, Cyrille F, Dunant, Sasan, Zandi, Andrea, Neumann, Ian, Plumb, Sergei, Doulatov, Jing, Chen, Craig, April, Jian-Bing, Fan, Norman, Iscove, John E, Dick
Publikováno v:
Cell Stem Cell
Summary Regulated blood production is achieved through the hierarchical organization of dormant hematopoietic stem cell (HSC) subsets that differ in self-renewal potential and division frequency, with long-term (LT)-HSCs dividing the least. The molec
Autor:
Anne-Claude Gingras, John E. Dick, Gerald D. Gish, Robert Herrington, Catherine Frelin, Jing Jin, Mark D. Minden, Julie Ruston, Tony Pawson, Igal Louria-Hayon, Jean Philippe Lambert, Hibret A. Adissu, Michael Milyavsky, Norman N. Iscove, Michael M. Kofler
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 110(51)
The Lnk (Sh2b3) adaptor protein dampens the response of hematopoietic stem cells and progenitors (HSPCs) to a variety of cytokines by inhibiting JAK2 signaling. As a consequence, Lnk(-/-) mice develop hematopoietic hyperplasia, which progresses to a