Implication of Reg I in Human Pancreatic Duct-like Cells In Vivo in the Pathological Pancreas and In Vitro During Exocrine Dedifferentiation

Autor: Julie Kerr-Conte, Didier Sanchez, Günter Klöppel, Michael E. Zenilman, Odette Guy-Crotte, Valery Gmyr, Catherine Figarella, François Pattou

Publikováno v: Pancreas. 29:14-21

A feature associated frequently with the pathologic pancreas is the presence of tubular complexes produced by a phenotypic modulation of acinar cells that take on the characteristics of ductular cells. Since the type I Reg gene, an acinar cell produc

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a005df24ca33692e3d4509d6ed4657ef
https://doi.org/10.1097/00006676-200407000-00050

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Autor: Sophie Degroote, Catherine Figarella, Philippe Delmotte, Philippe Roussel, Annie Bernigaud, Isabelle Van Seuningen, Marc Merten, Jean-Marc Perini

Publikováno v: Glycoconjugate Journal. 18:487-497

In order to investigate the influence of inflammation on the peripheral glycosylation of airway mucins, a human respiratory glandular cell line (MM-39) was treated by TNFalpha. The expression and the activity of sialyl- and fucosyl-transferases, invo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::759f5b9fd19ccf369bf7680c6bc291ad
https://doi.org/10.1023/a:1016038219183

Histidylated polylysine as a synthetic vector for gene transfer into immortalized cystic fibrosis airway surface and airway gland serous cells

Autor: Michel Monsigny, Chantal Pichon, Pascale Briand, Jean-Christophe Allo, Evelyne Souil, Patrick Midoux, Marc Merten, Catherine Figarella, Isabelle Fajac

Publikováno v: The Journal of Gene Medicine
The Journal of Gene Medicine, Wiley, 2000, 2 (5), pp.368-378. ⟨10.1002/1521-2254(200009/10)2:53.0.CO;2-F⟩

Background We recently designed a cationic polymer called histidylated polylysine made of polylysine partially substituted with histidyl residues which become protonated at slightly acidic pH. This polymer is thought to induce the leakage of acidic v

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d9afd9ca23d1d8e69c67079a4f7ea98c
https://doi.org/10.1002/1521-2254(200009/10)2:5<368::aid-jgm118>3.0.co

High lysosomal activities in cystic fibrosis tracheal gland cells corrected by adenovirus-mediated CFTR gene transfer

Autor: N. Bianco, D. Naı̈mi, Wafa Kammouni, Catherine Figarella, W. Renaud, M.D. Merten

Publikováno v: Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease. 1453(1):14-22

Human tracheal gland serous (HTGS) cells are now believed to be a major target of cystic fibrosis (CF) gene therapy. To evaluate the efficiency of adenovirus-mediated gene transfer in these cells we tested the adenovirus construction containing beta-

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd982d91d2a8465a5442816ed71ab068

Targeting of CFTR protein is linked to the polarization of human pancreatic duct cells in culture

Autor: Odette Guy-Crotte, Christiane Devaux, Etienne Hollande, Catherine Figarella, Marjorie Fanjul, Jurphas Van Rietschoten, Carine Chemin-Thomas, Sophie Demolombe

Publikováno v: European Journal of Cell Biology. 76:220-227

A relationship between targeting of the protein CFTR (Cystic Fibrosis Transmembrane conductance Regulator) and cellular polarization has been observed in various types of epithelial cells. However, there are no reports on this in human exocrine pancr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::248c864e5fa86e84b409355c9ce0263b
https://doi.org/10.1016/s0171-9335(98)80037-x