Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Catherine Farrokhi"'
Autor:
Robert N Pechnick, Svetlana Zonis, Kolja Wawrowsky, Rosemarie Cosgayon, Catherine Farrokhi, Liliana Lacayo, Vera Chesnokova
Publikováno v:
PLoS ONE, Vol 6, Iss 11, p e27290 (2011)
The relationships among hippocampal neurogenesis, depression and the mechanism of action of antidepressant drugs have generated a considerable amount of controversy. The cyclin-dependent kinase (Cdk) inhibitor p21(Cip1) (p21) plays a crucial role in
Externí odkaz:
https://doaj.org/article/b935c921fd924838bf4de3c0424dc712
Autor:
Chandramouli Chiruta, Catherine Farrokhi, Joshua Goldberg, David Schubert, Mariya Kopynets, Amanda J. Roberts, Marguerite Prior
Publikováno v:
Alzheimer's & Dementia. 12:678-686
Introduction Neurons die in Alzheimer's disease (AD) and are not effectively replaced. An alternative approach to maintain nerve cell number is to identify compounds that stimulate the proliferation of endogenous neural stem cells in old individuals
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7865b4a187de2378f3564fc3dc56583d
https://doi.org/10.1016/j.jalz.2016.03.016
https://doi.org/10.1016/j.jalz.2016.03.016
Autor:
Liliana M. Lacayo, Johnny Krasinkiewicz, Catherine Farrokhi, Mariana Puntel, Maria G. Castro, Kyle R. Kelson, Ghulam Muhammad A.K.M., Sukhpreet Kaur, Nathan VanderVeen, Philip Ng, Sean Kennedy, Robert N. Pechnick, Christopher Paran, Pedro R. Lowenstein, Ashley Appelhans, Kurt M. Kroeger, Alireza Salem, Donna Palmer, Chunyan Liu
Publikováno v:
Toxicology and Applied Pharmacology. 268:318-330
Adenoviral vectors (Ads) are promising gene delivery vehicles due to their high transduction efficiency; however, their clinical usefulness has been hampered by their immunogenicity and the presence of anti-Ad immunity in humans. We reported the effi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::249891079a70e919281c5cfa583d107b
https://doi.org/10.1016/j.taap.2013.02.001
https://doi.org/10.1016/j.taap.2013.02.001
Autor:
Oswald Quehenberger, Antonio Currais, Pamela Maher, David Schubert, Catherine Farrokhi, Aaron M. Armando, Richard Dargusch
Publikováno v:
The journals of gerontology. Series A, Biological sciences and medical sciences. 73(3)
Alzheimer's disease (AD) is rarely addressed in the context of aging even though there is an overlap in pathology. We previously used a phenotypic screening platform based on old age-associated brain toxicities to identify the flavonol fisetin as a p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90e72f3dd0fe356dc1a5cef44f1a4f84
https://pubmed.ncbi.nlm.nih.gov/28575152
https://pubmed.ncbi.nlm.nih.gov/28575152
Autor:
Eliezer Masliah, Jonathan Cook, Catherine Farrokhi, Jiqing Xu, Edward Rockenstein, Xin Jin, Kuo-Fen Lee, Fred de Winter, Michael Mante, Anthony Adame
Publikováno v:
Scientific Reports
Several lines of evidence suggest that neuregulin 1 (NRG1) signaling may influence cognitive function and neuropathology in Alzheimer’s disease (AD). To test this possibility, full-length type I or type III NRG1 was overexpressed via lentiviral vec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb69574081a04c1c202b49acd6b5dbe9
http://europepmc.org/articles/PMC4997345
http://europepmc.org/articles/PMC4997345
Autor:
Kyle R. Kelson, Philip Ng, Robert N. Pechnick, Pedro R. Lowenstein, Kurt M. Kroeger, Weidong Xiong, Alireza Salem, A.K.M. Ghulam Muhammad, Chunyan Liu, Donna Palmer, Liliana M. Lacayo, Mariana Puntel, Maria G. Castro, Catherine Farrokhi
Publikováno v:
Human Gene Therapy Methods. 23:271-284
Adenoviral vectors (Ads) have been evaluated in clinical trials for glioma. However, systemic immunity against the vectors can hamper therapeutic efficacy. We demonstrated that combined immunostimulation and cytotoxic gene therapy provides long-term
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::565076c4705b397a722a4a45202d5228
https://doi.org/10.1089/hgtb.2012.060
https://doi.org/10.1089/hgtb.2012.060
Autor:
Jieping Yang, Josee Bergeron, Maria G. Castro, James F. Curtin, Kevin C. Reyes, Robert N. Pechnick, Kurt M. Kroeger, Liliana M. Lacayo, Daniel Larocque, Pedro R. Lowenstein, Nicholas S. R. Sanderson, Mia Wibowo, Catherine Farrokhi, Niyati Bondale, Joe Girton
Publikováno v:
Articles
Soluble antigens diffuse out of the brain and can thus stimulate a systemic immune response, whereas particulate antigens (from infectious agents or tumor cells) remain within brain tissue, thus failing to stimulate a systemic immune response. Immune
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::742937c75a54b84ecb102802838f7157
https://doi.org/10.1073/pnas.0913496107
https://doi.org/10.1073/pnas.0913496107
Publikováno v:
Molecular psychiatry. 21(3)
Autism spectrum disorder (ASD) is a complex neurodevelopmental disorder of unknown etiology, but very likely resulting from both genetic and environmental factors. There is good evidence for immune system dysregulation in individuals with ASD. Howeve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::724aa9f68184aca3334a78c087cc4937
https://pubmed.ncbi.nlm.nih.gov/26055422
https://pubmed.ncbi.nlm.nih.gov/26055422
Autor:
Kevin C. Reyes, Jean-Philippe Vit, Charlene M. Manalo, Liliana M. Lacayo, Yasmin Bholat, Catherine Farrokhi, Robert N. Pechnick, Inna Spivak
Publikováno v:
Behavioural pharmacology. 22(3)
Acamprosate is used in the treatment of alcoholism; however, there is little information on its effects on nicotine addiction. The objective of this study was to determine whether acamprosate inhibits cue-induced relapse to nicotine self-administrati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::492ccd103e75630974f8334e43fb48c2
https://pubmed.ncbi.nlm.nih.gov/21522053
https://pubmed.ncbi.nlm.nih.gov/21522053
Autor:
David Foulad, Weidong Xiong, Gregory J. Baker, Kurt M. Kroeger, Maria G. Castro, Chunyan Liu, Philip Ng, James F. Curtin, Alireza Salem, Donna Palmer, Pedro R. Lowenstein, Niyati Bondale, Akm Ghulam Muhammad, Jonathan Lerner, Mariana Puntel, Kader Yagiz, Marianela Candolfi, Catherine Farrokhi, Robert N. Pechnick, Katherine E. Lawrence
Publikováno v:
Articles
Glioblastoma multiforme (GBM) is the most common and most aggressive primary brain tumor in humans. Systemic immunity against gene therapy vectors has been shown to hamper therapeutic efficacy; however, helper-dependent high-capacity adenovirus (HC-A
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4cdc53f3bef89146879fc1d267103d89
https://arrow.tudublin.ie/context/scschbioart/article/1053/viewcontent/Muhammad_AKM_Clin_Pharmacol_Ther_2010_for_Arrow.pdf
https://arrow.tudublin.ie/context/scschbioart/article/1053/viewcontent/Muhammad_AKM_Clin_Pharmacol_Ther_2010_for_Arrow.pdf
