Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Catherine F. Foulon"'
Autor:
Ming Kuan Chyan, Janna Quinn, Pradip M. Pathare, D. K. Hamlin, Michael R. Zalutsky, D. Scott Wilbur, Timothy J. Wedge, Robert L. Vessella, Reudi Risler, M. Frederick Hawthorne, Catherine F. Foulon, Brian B. Kegley
Publikováno v:
Bioconjugate Chemistry. 15:203-223
An investigation has been conducted to assess the in vivo stability of a series of astatinated benzamides and astatinated nido-carborane compounds in mice. It was hypothesized that the higher bond strength of boron-astatine bonds in the nido-carboran
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bbb2433b5e3315a4c567bf78abb40564
https://doi.org/10.1021/bc034175k
https://doi.org/10.1021/bc034175k
Publikováno v:
Nuclear Medicine and Biology. 28:769-777
Receptor-mediated internalization of monoclonal antibodies (mAbs), such as those specific for the epidermal growth factor receptor variant III (EGFRvIII), can lead to rapid loss of radioactivity from the target cell. In the current study, the anti-EG
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5936ac081f9c1fb9a0297a42790c8368
https://doi.org/10.1016/s0969-8051(01)00239-6
https://doi.org/10.1016/s0969-8051(01)00239-6
Autor:
Yinhua Yu, Catherine F. Foulon, Fengji Xu, Robert C. Bast, Michael R. Zalutsky, Xiao-Guang Zhao, Susan Slade, Donna J. Affleck
Publikováno v:
Nuclear Medicine and Biology. 26:781-790
Monoclonal antibody (MAb) internalization can have a major effect on tumor retention of radiolabel. Two anti-HER-2/neu MAbs (TA1 and 520C9) were radioiodinated using the iodogen, N-succinimidyl 5-iodo-3-pyridinecarboxylate (SIPC), and tyramine-cellob
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bfdaea089407bacb20e923fce0ce7209
https://doi.org/10.1016/s0969-8051(99)00060-8
https://doi.org/10.1016/s0969-8051(99)00060-8
Publikováno v:
Bioconjugate Chemistry. 10:867-876
Radioimmunopretargeting is based on the separate injection of a modified mAb and the radionuclide and most frequently exploits the very high avidity of biotin for streptavidin (SA). Currently, we are evaluating the therapeutic potential of directly l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eece3c4a1d6a63e4ab27c455d968b67b
https://doi.org/10.1021/bc990040w
https://doi.org/10.1021/bc990040w
Publikováno v:
Nuclear Medicine and Biology. 26:405-411
Monoclonal antibodies (MAbs) such as the anti-epidermal growth factor variant III (EGFRvIII) MAb L8A4 are rapidly internalized, which can lead to rapid loss of radioactivity from the tumor cell. The aim of this study was to evaluate the potential uti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09bfcfd9f10e59a411e9d783447d018e
https://doi.org/10.1016/s0969-8051(98)00120-6
https://doi.org/10.1016/s0969-8051(98)00120-6
Publikováno v:
Nuclear Medicine and Biology. 25:81-88
We report herein the preparation and biological evaluation of two radioastatinated biotin conjugates, (3-[211At]astatobenzoyl)norbiotinamide and ((5-[211At]astato-3-pyridinyl)carbonyl)norbiotinamide. Both conjugates were stable in the presence of hum
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5144d8070964cf3bac0a43e53c3c00f4
https://doi.org/10.1016/s0969-8051(97)00166-2
https://doi.org/10.1016/s0969-8051(97)00166-2
Publikováno v:
Bioconjugate Chemistry. 8:179-186
A new class of radioiodinated biotin conjugated is described in which the amido bond between biotin and the labeled prosthetic group is reversed. One conjugate, (3-[125I]iodobenzoyl)norbiotinamide (4c, [125I]IBB) was labeled with Na125I in one step f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24bc5c76d2291645c7815dd68077e796
https://doi.org/10.1021/bc970006m
https://doi.org/10.1021/bc970006m
Publikováno v:
Applied Radiation and Isotopes. 46:1039-1046
The fastest and most reliable preparation of radiolabeled 5-iodo-2′-deoxyuridine ([ 123/125/131 I]IUdR) is accomplished by iododemetallation. We describe a series of improvements to a previously published synthesis of radiolabeled IUdR by demercura
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb479bf0c5365c8efbfb62dee5e15935
https://doi.org/10.1016/0969-8043(95)00214-x
https://doi.org/10.1016/0969-8043(95)00214-x
Publikováno v:
Nuclear medicine and biology. 24(2)
Biotinyl-3-[ 211 At]astatoanilide ([ 211 At]AtBA) was prepared in more than 80% yield by destannylation. In vitro , [ 211 At]AtBA exhibited a high affinity for streptavidin, and was stable after incubation in human serum, cerebrospinal fluid and dist
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e7a3cc3516df720b593e07951ce1751
https://pubmed.ncbi.nlm.nih.gov/9089706
https://pubmed.ncbi.nlm.nih.gov/9089706