Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Catherine Ewen"'
Publikováno v:
Psychotherapeut. 67:204-212
Zusammenfassung Hintergrund Kognitive Verhaltenstherapie (KVT) ist bei Depression langfristig wirksam, jedoch besteht Verbesserungsbedarf. In der Forschung zum Placeboeffekt und der Neurowissenschaft wird die zentrale Bedeutung von Erwartungen immer
Autor:
Jack C. M. Dekkers, Raymond R. R. Rowland, Dinesh M. Thekkoot, Emily H. Waide, Jason W. Ross, Christopher K. Tuggle, Carol R. Wyatt, Catherine Ewen, Alyssa B. Evans, Nick V. L. Serão, N. Matthew Ellinwood, Nicholas J. Boddicker
Publikováno v:
The Journal of Immunology. 195:3171-3179
Mutations in >30 genes are known to result in impairment of the adaptive immune system, causing a group of disorders collectively known as SCID. SCID disorders are split into groups based on their presence and/or functionality of B, T, and NK cells.
Publikováno v:
Virus Research. 195:246-249
The replication of porcine reproductive and respiratory syndrome virus (PRRSV) was studied in a line of pigs possessing a severe combined immunodeficiency (SCID). Real-time RT-PCR revealed a unique course of infection for the SCID group. During the c
Autor:
Colin C. Anderson, Catherine Ewen, Govindarajan Thangavelu, Louis Boon, Kristofor K. Ellestad
Publikováno v:
European Journal of Immunology. 44:3560-3572
The expression of the coinhibitor PD-1 on T cells is important for the establishment of immune homeostasis. We previously found that PD-1 is particularly critical for the control of self-tolerance during lymphopenia-induced proliferation of recent th
Autor:
Melissa Samuel, Kristin M. Whitworth, Jonathan Lightner, Maureen A. Kerrigan, Catherine Ewen, Alan J. Mileham, David G. McLaren, Benjamin R. Trible, Randall S. Prather, Kevin D. Wells, Ada G. Cino-Ozuna, Raymond R. R. Rowland
Publikováno v:
Nature biotechnology. 34(1)
Autor:
Catherine Ewen, Neil MacDonald, Susan de Jong, Andy I. Kokaji, Steven M. Woodside, Allen C. Eaves, Terry E. Thomas
Publikováno v:
The Journal of Immunology. 200:174.38-174.38
Peripheral blood circulating T cells can be subdivided into either antigen experienced effector and memory T cells or naïve T cells that have not yet encountered their cognate antigen. Naïve T cells are valuable tools when studying mechanisms of T
Autor:
Catherine Ewen, Kevin Hankins, Melinda J. Wilkerson, K. M. Delph, Elizabeth G. Davis, Nora M. Bello
Publikováno v:
Journal of Equine Veterinary Science. 60:29-34.e1
Although there is a commercially available vaccine for Streptococcus equi subspecies equi licensed for the intranasal (IN) route of administration, some equine practitioners are administering this vaccine orally despite a lack of evidence for its eff
Autor:
Xin Zhou, Janet E. McElhaney, Dongxu Xie, Mary Beth Barry, Alison Kleppinger, W. David Hager, Yazhen Wang, Kevin P. Kane, Catherine Ewen, R. Chris Bleackley
Publikováno v:
Vaccine. 27:2418-2425
This study compared serum antibody titers and granzyme B (GrzB) levels in virus-stimulated peripheral blood mononuclear cells following influenza vaccination. Twelve of 239 older adults who subsequently developed laboratory-diagnosed influenza illnes
Autor:
Elliot Pittman, Brenda Duggan, Catherine Ewen, R. Chris Bleackley, Richard P. Fahlman, Marcelo Marcet-Palacios, Katia Carmine-Simmen
Publikováno v:
Protein engineering, designselection : PEDS. 28(1)
The intracellular roles of Granzyme B (GrB) in immune-mediated cell killing have been extensively studied. Recent data also implicate GrB in extracellular pathways of inflammation, cytokine activation and autoimmunity. Targeting (GrB) provides a new
Publikováno v:
The Journal of Immunology. 174:3212-3219
Calreticulin is an endoplasmic reticulum-resident chaperone that is stored in the cytotoxic granules of CTLs and NK cells and is released with granzymes and perforin upon recognition of target cells. To investigate the role of calreticulin in CTL-med