Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Catherine E. Scull"'
Publikováno v:
Frontiers in Molecular Biosciences, Vol 7 (2021)
Transcriptional riboswitches involve RNA aptamers that are typically found in the 5′ untranslated regions (UTRs) of bacterial mRNAs and form alternative secondary structures upon binding to cognate ligands. Alteration of the riboswitch's secondary
Externí odkaz:
https://doaj.org/article/59ba54e728554486be11dba23521db04
Autor:
Brittany L Ford, Ting Wei, Hester Liu, Catherine E Scull, Saman M Najmi, Stephanie Pitts, Wenjun Fan, David A Schneider, Marikki Laiho
Publikováno v:
PLoS ONE, Vol 18, Iss 5, p e0285660 (2023)
RNA Polymerase I (Pol I) has recently been recognized as a cancer therapeutic target. The activity of this enzyme is essential for ribosome biogenesis and is universally activated in cancers. The enzymatic activity of this multi-subunit complex resid
Externí odkaz:
https://doaj.org/article/deb9e959af1549c0995c621a11a4bf5f
Autor:
Schneider, Catherine E. Scull, Guy Twa, Yinfeng Zhang, Naiheng J. Yang, Robert N. Hunter, Corinne E. Augelli-Szafran, David A.
Publikováno v:
Cancers; Volume 15; Issue 13; Pages: 3303
Cancer cells are especially sensitive to perturbations in ribosome biogenesis as they rely on finely tuned protein homeostasis to facilitate their rapid growth and proliferation. While ribosome synthesis and cancer have a well-established relationshi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=multidiscipl::68088956c07b93ab00435f0b42d7d292
Autor:
Aaron T. Blanchard, Zi Li, Elizabeth C. Duran, Catherine E. Scull, J. Damon Hoff, Keenan R. Wright, Victor Pan, Nils G. Walter
Publikováno v:
Nano Lett
DNA-based FluoroCubes were recently developed as a solution to photobleaching, a ubiquitous limitation of fluorescence microscopy (Niekamp, Stuurman, & Vale, Nature Methods, 2020). FluoroCubes – compact ~4×4×5.4nm(3) four-helix bundles bound by
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e1ea601bdd4988a7bd4866ec0325667
https://europepmc.org/articles/PMC10080265/
https://europepmc.org/articles/PMC10080265/
Publikováno v:
Biophys J
Eukaryotes express three DNA-dependent RNA polymerases (Pols) that are responsible for the entirety of cellular genomic expression. The three Pols have evolved to express specific cohorts of RNAs and thus have diverged both structurally and functiona
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19f3e31a0b5197c32964d0cff071108c
https://doi.org/10.1016/j.bpj.2021.03.007
https://doi.org/10.1016/j.bpj.2021.03.007
Publikováno v:
J Biol Chem
The sequence of the DNA template has long been thought to influence the rate of transcription by DNA-dependent RNA polymerases, but the influence of DNA sequence on transcription elongation properties of eukaryotic RNA polymerase I (Pol I) fromSaccha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0acb642e7a3f28f15c821c078981b35c
https://doi.org/10.1016/s0021-9258(17)49886-3
https://doi.org/10.1016/s0021-9258(17)49886-3
Autor:
Catherine E. Scull, David A. Schneider
Publikováno v:
Trends Genet
Ribosomal RNA (rRNA) is co-and post-transcriptionally processed into active ribosomes. This process is dynamically regulated by direct covalent modifications of the polymerase that synthesizes the rRNA, RNA polymerase I (Pol I), and by interactions w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54da1f6de5ef5a12da1b3795aee496b7
https://doi.org/10.1016/j.tig.2019.07.002
https://doi.org/10.1016/j.tig.2019.07.002
Autor:
Aaron T. Blanchard, Zi Li, Elizabeth C. Duran, Catherine E. Scull, J. Damon Hoff, Keenan R. Wright, Victor Pan, Nils G. Walter
Publikováno v:
Nano Letters. 22:8032-8032
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9487c9a4dc379aee1cfc6a1f14bb52b2
https://doi.org/10.1021/acs.nanolett.2c03349
https://doi.org/10.1021/acs.nanolett.2c03349
Publikováno v:
Frontiers in Molecular Biosciences, Vol 7 (2021)
Frontiers in Molecular Biosciences
Frontiers in Molecular Biosciences
Transcriptional riboswitches involve RNA aptamers that are typically found in the 5′ untranslated regions (UTRs) of bacterial mRNAs and form alternative secondary structures upon binding to cognate ligands. Alteration of the riboswitch's secondary
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1a26fab7a00962e2e9d960731dc5196
https://www.frontiersin.org/articles/10.3389/fmolb.2020.607158/full
https://www.frontiersin.org/articles/10.3389/fmolb.2020.607158/full
Publikováno v:
Biochemistry. 58(16)
Eukaryotic cells express at least three nuclear RNA polymerases (Pols), each with a unique set of gene targets. Though these enzymes are homologous, there are many differences among the Pols. In this study, a novel assay for Pol I transcription elong
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c00130715da965f72a664254305b5e02
https://pubmed.ncbi.nlm.nih.gov/30912638
https://pubmed.ncbi.nlm.nih.gov/30912638