Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Catherine E. Kuzmicki"'
Autor:
Jason T. Forys, Catherine E. Kuzmicki, Anthony J. Saporita, Crystal L. Winkeler, Leonard B. Maggi, Jr., Jason D. Weber
Publikováno v:
Cell Reports, Vol 7, Iss 2, Pp 514-526 (2014)
Summary: The ARF and p53 tumor suppressors are thought to act in a linear pathway to prevent cellular transformation in response to various oncogenic signals. Here, we show that loss of p53 leads to an increase in ARF protein levels, which function t
Externí odkaz:
https://doaj.org/article/eaa17c2fcc3c482b9fcfd53d0e85ad7e
Autor:
Che-Pei Kung, Emily A. Bross, Catherine E. Kuzmicki, Michael Benjamin, Leonard B. Maggi, Jason D. Weber
Publikováno v:
Journal of Clinical and Translational Science, Vol 2, Pp 34-34 (2018)
OBJECTIVES/SPECIFIC AIMS: Triple-negative breast cancer (TNBC) accounts for one-fifth of the breast cancer patient population. The heterogeneous nature of TNBC and lack of options for targeted therapy make its treatment a constant adventure. The defi
Externí odkaz:
https://doaj.org/article/0ab77ba060ee4ba0ad0038e0a0583d8d
Autor:
Corey L Anderson, Catherine E Kuzmicki, Ryan R Childs, Caleb J Hintz, Craig T January, Ravi C Balijepalli
Publikováno v:
Circulation. 132
Introduction: Hundreds of HERG potassium channel mutations are linked to type 2 Long QT Syndrome (LQT2). Most mutations are trafficking defective but correctable by culturing cells at reduced temperature (27 C) or with the pore blocker E4031. For a f
Autor:
Catherine E. Kuzmicki, Craig T. January, Corey L. Anderson, Caleb J. Hintz, Brian P. Delisle, Ryan R. Childs
Publikováno v:
Nature communications
It has been suggested that deficient protein trafficking to the cell membrane is the dominant mechanism associated with type 2 Long QT syndrome (LQT2) caused by Kv11.1 potassium channel missense mutations, and that for many mutations the trafficking