Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Catherine E. Goodfellow"'
Autor:
Bėla Horváth, Partha Mukhopadhyay, Rachel Y. Gao, Pal Pacher, Galin Tanchian, Magid Lital, Mohanraj Rajesh, Raphael Mechoulam, Michelle Glass, Ogyi Park, Sandor Batkai, Catherine E. Goodfellow
Publikováno v:
British Journal of Pharmacology. 165:2462-2478
BACKGROUND AND PURPOSE Cannabinoid CB2 receptor activation has been reported to attenuate myocardial, cerebral and hepatic ischaemia-reperfusion (I/R) injury. EXPERIMENTAL APPROACH We have investigated the effects of a novel CB2 receptor agonist ((1S
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cf195d2535e65f2adac3b4e44b078174
https://doi.org/10.1111/j.1476-5381.2011.01381.x
https://doi.org/10.1111/j.1476-5381.2011.01381.x
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular Cell Research. 1813(8):1554-1560
Cannabinoid receptor 2 (CB2) is a GPCR highly expressed on the surface of cells of the immune system, supporting its role in immunomodulation. This study has investigated the trafficking properties of this receptor when stably expressed by HEK-293 ce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f1ed529e9b2a8b977f2c7c1312c2114
Publikováno v:
Journal of Neuroscience Research. 89:1685-1697
The limited availability and potential to culture primary human brain cells means that there is still a need for cell lines that reliably model human neurons and glial cells. The human-derived NTera2/D1 (NT2) cell line is a promising tool from which
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::726d18db73f222bdd9a9712eadaa5758
https://doi.org/10.1002/jnr.22692
https://doi.org/10.1002/jnr.22692
Publikováno v:
British Journal of Pharmacology. 160:747-761
Background and purpose: The therapeutic potential of cannabinoids in Huntington's disease (HD) has been investigated by several groups with complex and sometimes contrasting results. We sought to examine key points of intersection between cannabinoid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5d2fc3c671d46df384f43b8ce1da2ef7
https://doi.org/10.1111/j.1476-5381.2010.00773.x
https://doi.org/10.1111/j.1476-5381.2010.00773.x
Publikováno v:
Journal of Molecular Biology. 355:784-797
Mycobacterium tuberculosis , the cause of tuberculosis, presents a major threat to human health worldwide. Biosynthetic enzymes that are essential for the survival of the bacterium, especially in activated macrophages, are important potential drug ta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58f10a761f38fe98befd3d3a8da43598
https://doi.org/10.1016/j.jmb.2005.11.016
https://doi.org/10.1016/j.jmb.2005.11.016
Publikováno v:
Vitamins and hormones. 81
In the 15 years since its discovery anandamide has been implicated in many physiological processes. The signaling pathways mediating many of these processes are now coming to light, particularly in the CNS. The complexity of the cannabinoid system an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::db877163957a8999a700d04d4e9b3afd
https://pubmed.ncbi.nlm.nih.gov/19647109
https://pubmed.ncbi.nlm.nih.gov/19647109
In the 15 years since its discovery anandamide has been implicated in many physiological processes. The signaling pathways mediating many of these processes are now coming to light, particularly in the CNS. The complexity of the cannabinoid system an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6e4468447a5079fca177624880c56d17
https://doi.org/10.1016/s0083-6729(09)81004-2
https://doi.org/10.1016/s0083-6729(09)81004-2
Autor:
Megan J. Dowie, Emma L. Scotter, Catherine E. Goodfellow, E. Scott Graham, Michelle Glass, Natasha L. Grimsey
Publikováno v:
Journal of neuroscience methods. 171(1)
The study of endogenous cannabinoid CB1 receptor proteins in neuronal tissues and cells relies on the availability of highly specific antibodies. We have tested the ability of a series of CB1 antibodies to detect endogenous receptors in brain as well
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::529233d4e19fef83a45f28594ffe114c
https://pubmed.ncbi.nlm.nih.gov/18406468
https://pubmed.ncbi.nlm.nih.gov/18406468