Zobrazeno 1 - 10
of 431
pro vyhledávání: '"Catherine E Costello"'
Autor:
Pamela Magistrado-Coxen, Yousuf Aqeel, Angelo Lopez, John R Haserick, Breeanna R Urbanowicz, Catherine E Costello, John Samuelson
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 13, Iss 5, p e0007352 (2019)
BackgroundAcanthamoeba castellanii, which causes keratitis and blindness in under-resourced countries, is an emerging pathogen worldwide, because of its association with contact lens use. The wall makes cysts resistant to sterilizing reagents in lens
Externí odkaz:
https://doaj.org/article/614497fdf9cd46d5ac998e60b7f4b006
Publikováno v:
PLoS ONE, Vol 12, Iss 8, p e0182395 (2017)
Cryptosporidium parvum (studied here) and Cryptosporidium hominis are important causes of diarrhea in infants and immunosuppressed persons. C. parvum vaccine candidates, which are on the surface of sporozoites, include glycoproteins with Ser- and Thr
Externí odkaz:
https://doaj.org/article/5ef6d8e65aac4ac7bc774257795dd423
Autor:
Chunxiang Yao, Jessica B Behring, Di Shao, Aaron L Sverdlov, Stephen A Whelan, Aly Elezaby, Xiaoyan Yin, Deborah A Siwik, Francesca Seta, Catherine E Costello, Richard A Cohen, Reiko Matsui, Wilson S Colucci, Mark E McComb, Markus M Bachschmid
Publikováno v:
PLoS ONE, Vol 10, Iss 12, p e0144025 (2015)
Reactive protein cysteine thiolates are instrumental in redox regulation. Oxidants, such as hydrogen peroxide (H2O2), react with thiolates to form oxidative post-translational modifications, enabling physiological redox signaling. Cardiac disease and
Externí odkaz:
https://doaj.org/article/17226e23b1354d9a9df939a220b367f6
Autor:
Aparajita Chatterjee, Andrea Carpentieri, Daniel M Ratner, Esther Bullitt, Catherine E Costello, Phillips W Robbins, John Samuelson
Publikováno v:
PLoS Pathogens, Vol 6, Iss 8, p e1001059 (2010)
The infectious and diagnostic stage of Giardia lamblia (also known as G. intestinalis or G. duodenalis) is the cyst. The Giardia cyst wall contains fibrils of a unique beta-1,3-linked N-acetylgalactosamine (GalNAc) homopolymer and at least three cyst
Externí odkaz:
https://doaj.org/article/66fab067d50b4866ba818ca1e2e623ca
Autor:
Ellena Nador, Chaoshuang Xia, Philip J. Santangelo, Kevin J. Whaley, Catherine E. Costello, Deborah J. Anderson
Publikováno v:
Antibodies, Vol 13, Iss 1, p 17 (2024)
IgG Fc N-glycosylation is necessary for effector functions and is an important component of quality control. The choice of antibody manufacturing platform has the potential to significantly influence the Fc glycans of an antibody and consequently alt
Externí odkaz:
https://doaj.org/article/f4115ee49a3541d4afd575326cb5cb11
Autor:
Korawit Kanjana, Klemen Strle, Robert B. Lochhead, Annalisa Pianta, Laura M. Mateyka, Qi Wang, Sheila L. Arvikar, David E. Kling, Cameron A. Deangelo, Lucy Curham, Alan G. Barbour, Catherine E. Costello, James J. Moon, Allen C. Steere
Publikováno v:
The Journal of Clinical Investigation, Vol 133, Iss 17 (2023)
BACKGROUND Autoimmune diseases often have strong genetic associations with specific HLA-DR alleles. The synovial lesion in chronic inflammatory forms of arthritis shows marked upregulation of HLA-DR molecules, including in postinfectious Lyme arthrit
Externí odkaz:
https://doaj.org/article/a775241c4c164c029eb30c87de7b5e80
Autor:
Saran Lotfollahzadeh, Chaoshuang Xia, Razie Amraei, Ning Hua, Konstantin V. Kandror, Stephen R. Farmer, Wenyi Wei, Catherine E. Costello, Vipul Chitalia, Nader Rahimi
Publikováno v:
Molecular Metabolism, Vol 73, Iss , Pp 101744- (2023)
Objective: Obesity is a complex disorder and is linked to chronic diseases such as type 2 diabetes. Major intrinsically disordered NOTCH2-associated receptor2 (MINAR2) is an understudied protein with an unknown role in obesity and metabolism. The pur
Externí odkaz:
https://doaj.org/article/4ab846303ffe4f03a409db021e6fe8fc
Autor:
Nader Rahimi, Mitchell R. White, Razie Amraei, Saran Lotfollahzadeh, Chaoshuang Xia, Marek Michalak, Catherine E. Costello, Elke Mühlberger
Publikováno v:
Cells, Vol 12, Iss 23, p 2694 (2023)
Cardiovascular complications are major clinical hallmarks of acute and post-acute coronavirus disease 2019 (COVID-19). However, the mechanistic details of SARS-CoV-2 infectivity of endothelial cells remain largely unknown. Here, we demonstrate that t
Externí odkaz:
https://doaj.org/article/a9c4c5004bfe4d879ee797058f0f4e62
Autor:
Hanke, Wel, Ana Maria, Garcia, Elisabet, Gas-Pascual, Macy M, Willis, Hyun W, Kim, Giulia, Bandini, Maissa Mareme, Gaye, Catherine E, Costello, John, Samuelson, Christopher M, West
Publikováno v:
Glycobiology. 33:225-244
O-GlcNAcylation is a prominent modification of nuclear and cytoplasmic proteins in animals and plants and is mediated by a single O-GlcNAc transferase (OGT). Spindly (Spy), a paralog of OGT first discovered in higher plants, has an ortholog in the ap
Publikováno v:
Arthritis & Rheumatology.