Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Catherine Doller"'
Publikováno v:
The Journal of Neuroscience. 24:6531-6539
We have developed a novelin vitromodel of the glial scar that mimics the gradient of proteoglycan foundin vivoafter spinal cord injury. In this model, regenerated axons from adult sensory neurons that extended deeply into the gradient developed bulbo
Autor:
Catherine Doller, Sucai Dong, Jerry Silver, Katherine Temple, Barbara Grimpe, Alfred T. Malouf
Publikováno v:
The Journal of Neuroscience. 22:3144-3160
We have addressed the question of whether a family of axon growth-promoting molecules known as the laminins may play a role during axon regeneration in the CNS. A narrow sickle-shaped region containing a basal lamina-independent form of laminin exist
Autor:
Heather Butler, Ram H. Nagaraj, Moonkyung H Caprara, Catherine Doller, Lixing W. Reneker, Magdalena Staniszewska, Maneesh Mailankot, Benlian Wang, Scott Howell
Publikováno v:
Laboratory investigation; a journal of technical methods and pathology
Indoleamine 2,3-dioxygenase (IDO) is the first enzyme in the kynurenine pathway. The kynurenines formed in this pathway chemically modify proteins and cause apoptosis in cells. Evidence suggests that kynurenines and their protein modifications are in
Although it has been suggested that astroglia guide pioneering axons during development, the cellular and molecular substrates that direct axon regeneration in adult white matter have not been elucidated. We show that although adult cortical neurons
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b467139ccd2d4bf2304edc1f5983adb3
https://europepmc.org/articles/PMC6730112/
https://europepmc.org/articles/PMC6730112/
Publikováno v:
The Journal of Immunology. 192:178.17-178.17
The activation and survival of T cells are both essential for the development and progression of uveitis. Cyclin-dependent kinas 5 (Cdk5) is a unique member of Cdk family that forms a complex with p35 (CDK5R1) and modulates the function of many prote
Publikováno v:
The Journal of neuroscience : the official journal of the Society for Neuroscience. 19(19)
Post-traumatic cystic cavitation, in which the size and severity of a CNS injury progress from a small area of direct trauma to a greatly enlarged secondary injury surrounded by glial scar tissue, is a poorly understood complication of damage to the
Robust regeneration of adult sensory axons in degenerating white matter of the adult rat spinal cord
Publikováno v:
The Journal of neuroscience : the official journal of the Society for Neuroscience. 19(14)
We have recently reported that minimally disturbed adult CNS white matter can support regeneration of adult axons by using a novel microtransplantation technique to inject minute volumes of dissociated adult rat dorsal root ganglion neurons directly
Publikováno v:
Experimental neurology. 149(2)
We have developed an in vitro model in which isolated senile plaque (SP) cores are presented to rat microglial cells in culture. Microglia rapidly phagocytosed, broke apart, and cleared SP cores. However, when cocultured with astrocytes, microglial p
Autor:
Rachel R. Caspi, Catherine Doller, Yan Li, Chi-Chao Chan, John J. Fung, Zhidan Tu, Lina Lu, Sunao Sugita, Dawn Smith, Feng Lin, Shiguang Qian
Publikováno v:
Investigative Opthalmology & Visual Science. 53:959
To test whether retinal pigment epithelial (RPE) cells are able to induce myeloid-derived suppressor cell (MDSC) differentiation from bone marrow (BM) progenitors.BM cells were cocultured with or without RPE cells in the presence of GM-CSF and IL-4.
Publikováno v:
Developmental biology. 156(1)
The dorsal root entry zone (DREZ) of the spinal cord is the interface between the central and peripheral nervous systems and is the pathway through which sensory afferents enter the central nervous system during development. However, in the rat, the