Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Catherine Diener"'
Autor:
Lothar Lindemann, Michal Stawarski, Ruth C. Werthmann, Jens Lamerz, Catherine Diener, Christophe Fischer, Thorsten Fritzius, Martin Gassmann, Angélique Augustin, Luca Trovò, Bernhard Bettler, Adi Raveh, Manuel Tzouros
Publikováno v:
Neuropharmacology. 190:108426
For a long time metabotropic glutamate receptors (mGluRs) were thought to regulate neuronal functions as obligatory homodimers. Recent reports, however, indicate the existence of heterodimers between group-II and -III mGluRs in the brain, which diffe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c73f87087a186e1c3ef8d0d145dac862
https://doi.org/10.1016/j.neuropharm.2020.108426
https://doi.org/10.1016/j.neuropharm.2020.108426
Autor:
Gerhard Hoffmann, Will Spooren, Eric Prinssen, Silvia Gatti, Thomas Hartung, Michael Honer, Neil Parrott, Bernd Büttelmann, Lothar Lindemann, Porter Richard Hugh Phillip, Georg Jaeschke, Christophe Fischer, Sabine Kolczewski, Eric Vieira, Aubin Michalon, Christophe Flament, Joseph G. Wettstein, Catherine Diener
Publikováno v:
Journal of Pharmacology and Experimental Therapeutics. 339:474-486
The metabotropic glutamate receptor 5 (mGlu5) is a glutamate-activated class C G protein-coupled receptor widely expressed in the central nervous system and clinically investigated as a drug target for a range of indications, including depression, Pa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2bd76b52481ac1f6b61f6cb201859d2
https://doi.org/10.1124/jpet.111.185660
https://doi.org/10.1124/jpet.111.185660
Autor:
Natalie‑Anne Ward, Andreas Mühlemann, Pari Malherbe, Georg Jaeschke, Nicole A. Kratochwil, Andy Stucki, Porter Richard Hugh Phillip, Catherine Diener, Christophe Fischer
Publikováno v:
European Journal of Pharmacology. 529:95-104
Several mutations in the seven-transmembrane region of rat metabotropic glutamate 5 (rmGlu5) receptors were produced by site-directed mutagenesis and expressed in CHO cells. Using functional intracellular calcium ([Ca(2+)](i)) mobilisation, we identi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48f8b34a82c16e96b36716376ee6efb2
https://doi.org/10.1016/j.ejphar.2005.11.008
https://doi.org/10.1016/j.ejphar.2005.11.008
Autor:
Porter Richard Hugh Phillip, Jenny Piussi, Andreas Mühlemann, Andy Stucki, Christophe Fischer, Catherine Diener
Publikováno v:
British Journal of Pharmacology. 144:1118-1125
1 Several combinations of cysteine to serine mutations at positions 57, 93, 99 and 129 in the extracellular N-terminal domain of human metabotropic 5a (hmGlu5a) receptors were produced and expressed in HEK293 cells. Quisqualic acid-induced intracellu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3e6891ae37f72f55551b358d9f34af2e
https://doi.org/10.1038/sj.bjp.0706152
https://doi.org/10.1038/sj.bjp.0706152
Autor:
Christophe Fischer, Marie-Théeése Zenner, Nicole A. Kratochwil, Catherine Diener, Claudia Kratzeisen, Porter Richard Hugh Phillip, Jenny Piussi, Pari Malherbe
Publikováno v:
Molecular Pharmacology. 64:823-832
Metabotropic glutamate (mGlu) 5 is a G-protein-coupled metabotropic glutamate receptor that plays an important role as a modulator of synaptic plasticity, ion channel activity, and excitotoxicity. 2-Methyl-6-(phenylethynyl)-pyridine (MPEP) is a highl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::927ad161812f783a01a4e6f9f81d7e86
https://doi.org/10.1124/mol.64.4.823
https://doi.org/10.1124/mol.64.4.823
Autor:
Eric Prinssen, Manfred Brockhaus, Hansruedi Loetscher, Jennifer L. Beck, Helmut Jacobsen, Diana Schuhbauer, Joseph G. Wettstein, Lothar Lindemann, Christophe Schweitzer, Dieter P. Reinhardt, Silvia Gatti Mcarthur, Christophe Fischer, Catherine Diener
Publikováno v:
The FASEB Journal. 22:671-671
Oseltamivir is a potent and selective inhibitor of the influenza virus neuraminidases, specifically targeting influenza virus A- and B-subtypes including the A/H5N1 influenza virus. To date, the dr...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ba713ab0ee9de84fd888a4620f2b9839
https://doi.org/10.1096/fasebj.22.2_supplement.671
https://doi.org/10.1096/fasebj.22.2_supplement.671
Autor:
Pari, Malherbe, Nicole, Kratochwil, Marie-Thrse, Zenner, Jenny, Piussi, Catherine, Diener, Claudia, Kratzeisen, Christophe, Fischer, P, Porter Richard H
Publikováno v:
Molecular Pharmacology; October 2003, Vol. 64 Issue: 4 p823-32, 10p