Zobrazeno 1 - 10
of 175
pro vyhledávání: '"Catherine C. Hedrick"'
Autor:
Omar M. Makram, Harikrishnan Hyma Kunhiraman, Ryan A. Harris, Catherine C. Hedrick, Khurram Nasir, Neal L. Weintraub, Xiaoling Wang, Avirup Guha
Publikováno v:
American Heart Journal Plus, Vol 40, Iss , Pp 100380- (2024)
Introduction: This study aimed to investigate the relationship between risk factors of cancer among individuals with existing cardiovascular disease (CVD). Methods: The analysis included 438 and 2100 CVD patients aged 65+ from NHANES-III and Continuo
Externí odkaz:
https://doaj.org/article/a46da870650e43c789f38d61d337a952
Autor:
Nandini Chatterjee, Ravi K. Komaravolu, Christopher P. Durant, Runpei Wu, Chantel McSkimming, Fabrizio Drago, Sunil Kumar, Gabriel Valentin-Guillama, Yury I. Miller, Coleen A. McNamara, Klaus Ley, Angela Taylor, Ahmad Alimadadi, Catherine C. Hedrick
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 5, p 2894 (2024)
Monocytes are associated with human cardiovascular disease progression. Monocytes are segregated into three major subsets: classical (cMo), intermediate (iMo), and nonclassical (nMo). Recent studies have identified heterogeneity within each of these
Externí odkaz:
https://doaj.org/article/d65c30b4e2994c06bcbc7392a8e0b48f
Autor:
Melissa A. Meyer, Huy Q. Dinh, Ahmad Alimadadi, Daniel J. Araujo, Nandini Chatterjee, Norma A. Gutierrez, Yanfang Peipei Zhu, Emma L. Hunter, Shu Liang, Gregory Seumois, William B. Kiosses, Sergio D. Catz, Pandurangan Vijayanand, Christian Ottensmeier, Catherine C. Hedrick
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
PurposeDue to their abundance in the blood, low RNA content, and short lifespan, neutrophils have been classically considered to be one homogenous pool. However, recent work has found that mature neutrophils and neutrophil progenitors are composed of
Externí odkaz:
https://doaj.org/article/bf6b900ace434ede9efa62d8dbe73cc9
Autor:
Shahad Iqneibi, Ryosuke Saigusa, Amir Khan, Mohammad Oliaeimotlagh, Sujit Silas Armstrong Suthahar, Sunil Kumar, Ahmad Alimadadi, Christopher P. Durant, Yanal Ghosheh, Coleen A. McNamara, Catherine C. Hedrick, Klaus Ley
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Coronary artery disease (CAD) is a major cause of death worldwide. The role of CD8+ T cells in CAD is unknown. Recent studies suggest a breakdown of tolerance in atherosclerosis, resulting in active T cell receptor (TCR) engagement with self-antigens
Externí odkaz:
https://doaj.org/article/06e37518823a4d04818e99cb80e328fc
Autor:
Lindsey E. Padgett, Paola M. Marcovecchio, Claire E. Olingy, Daniel J. Araujo, Kathleen Steel, Huy Q. Dinh, Ahmad Alimadadi, Yanfang Peipei Zhu, Melissa A. Meyer, William B. Kiosses, Graham D. Thomas, Catherine C. Hedrick
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
CD8+ T cells drive anti-cancer immunity in response to antigen-presenting cells such as dendritic cells and subpopulations of monocytes and macrophages. While CD14+ classical monocytes modulate CD8+ T cell responses, the contributions of CD16+ noncla
Externí odkaz:
https://doaj.org/article/c4df218d6f674ff49fed2a766ea2cf59
Autor:
Jennifer L. Johnson, Elsa Meneses-Salas, Mahalakshmi Ramadass, Jlenia Monfregola, Farhana Rahman, Raquel Carvalho Gontijo, William B. Kiosses, Kersi Pestonjamasp, Dale Allen, Jinzhong Zhang, Douglas G. Osborne, Yanfang Peipei Zhu, Nathan Wineinger, Kasra Askari, Danni Chen, Juan Yu, Scott C. Henderson, Catherine C. Hedrick, Matilde Valeria Ursini, Sergio Grinstein, Daniel D. Billadeau, Sergio D. Catz
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-24 (2022)
Responsive exocytosis in neutrophil leukocytes involves actin depolymerisation-dependent sequential release of gelatinase granules, then strongly pro-inflammatory azurophilic granules. Here authors show that the actin nucleator protein WASH facilitat
Externí odkaz:
https://doaj.org/article/9638c498eebb49f28ed25260528bc5a9
Autor:
Jenifer Vallejo, Ryosuke Saigusa, Rishab Gulati, Sujit Silas Armstrong Suthahar, Vasantika Suryawanshi, Ahmad Alimadadi, Christopher P. Durant, Yanal Ghosheh, Payel Roy, Erik Ehinger, Tanyaporn Pattarabanjird, David B. Hanna, Alan L. Landay, Russell P. Tracy, Jason M. Lazar, Wendy J. Mack, Kathleen M. Weber, Adaora A. Adimora, Howard N. Hodis, Phyllis C. Tien, Igho Ofotokun, Sonya L. Heath, Avishai Shemesh, Coleen A. McNamara, Lewis L. Lanier, Catherine C. Hedrick, Robert C. Kaplan, Klaus Ley
Publikováno v:
BMC Biology, Vol 20, Iss 1, Pp 1-19 (2022)
Abstract Background Cryopreserved peripheral blood mononuclear cells (PBMCs) are frequently collected and provide disease- and treatment-relevant data in clinical studies. Here, we developed combined protein (40 antibodies) and transcript single-cell
Externí odkaz:
https://doaj.org/article/02a45738c2a44c44b7e9d1b98a16d7b0
Autor:
Hannah Hillman, Nabeela Khan, Akul Singhania, Paige Dubelko, Ferran Soldevila, Rashmi Tippalagama, Aruna D. DeSilva, Bandu Gunasena, Judy Perera, Thomas J. Scriba, Cynthia Ontong, Michelle Fisher, Angelique Luabeya, Randy Taplitz, Gregory Seumois, Pandurangan Vijayanand, Catherine C. Hedrick, Bjoern Peters, Julie G. Burel
Publikováno v:
Frontiers in Immunology, Vol 13 (2023)
IntroductionPrevious studies suggest that monocytes are an important contributor to tuberculosis (TB)-specific immune signatures in blood.MethodsHere, we carried out comprehensive single-cell profiling of monocytes in paired blood samples of active T
Externí odkaz:
https://doaj.org/article/fd2683604621403589ee1f57436e33e4
Autor:
Huy Q. Dinh, Feng Pan, Geng Wang, Qing-Feng Huang, Claire E. Olingy, Zhi-Yong Wu, Shao-Hong Wang, Xin Xu, Xiu-E Xu, Jian-Zhong He, Qian Yang, Sandra Orsulic, Marcela Haro, Li-Yan Li, Guo-Wei Huang, Joshua J. Breunig, H. Phillip Koeffler, Catherine C. Hedrick, Li-Yan Xu, De-Chen Lin, En-Min Li
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
The microenvironment of oesophageal squamous cell carcinomas (ESCC) is heterogeneous and can strongly impact response to treatment. Here, the authors characterize the ESCC tumour microenvironment with single-cell RNA-seq, finding CST1 + myofibroblast
Externí odkaz:
https://doaj.org/article/2e80dc52b5e14a5c9cab19a0f4a82e35
Autor:
Claire Olingy, Ahmad Alimadadi, Daniel J. Araujo, David Barry, Norma A. Gutierrez, Max Hardy Werbin, Edurne Arriola, Sandip Pravin Patel, Christian H. Ottensmeier, Huy Q. Dinh, Catherine C. Hedrick
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Non-small cell lung carcinoma (NSCLC) is the leading cause of cancer-related deaths globally. Immune checkpoint blockade (ICB) has transformed cancer medicine, with anti-programmed cell death protein 1 (anti-PD-1) therapy now well-utilized for treati
Externí odkaz:
https://doaj.org/article/1269b37320e04f1fb1151f73ee5673c6