Zobrazeno 1 - 10
of 41
pro vyhledávání: '"Catherine Broome"'
Autor:
Catherine Broome
Publikováno v:
Therapeutic Advances in Hematology, Vol 14 (2023)
Primary immune thrombocytopenia (ITP) is an acquired autoimmune disorder characterized by isolated thrombocytopenia. Most patients with ITP have antiplatelet antibodies of the immunoglobulin G (IgG) subtype which through interaction with platelet and
Externí odkaz:
https://doaj.org/article/3153ab6427dd42aeb663e41fdcba33e7
Autor:
Philip A. McFarlane, Martin Bitzan, Catherine Broome, Dana Baran, Jocelyn Garland, Louis-Philippe Girard, Kuljit Grewal, Anne-Laure Lapeyraque, Christopher Jordan Patriquin, Katerina Pavenski, Christoph Licht
Publikováno v:
Canadian Journal of Kidney Health and Disease, Vol 8 (2021)
Purpose of review: Thrombotic microangiopathy (TMA) is suspected in patients presenting with thrombocytopenia and evidence of a microangiopathic hemolytic anemia. Patients with TMA can be critically ill, so rapid and accurate identification of the un
Externí odkaz:
https://doaj.org/article/ec3e20004dbc4da7ae2ac0595c5deed5
Autor:
Kelly Gwathmey, Catherine Broome, Matthias Goebeler, Hiroyuki Murai, Zsuzsanna Bata-Csorgo, Adrian Newland, Peter Ulrichts, Rene Kerstens, Jeffrey Guptill, Sofiane Agha, Ming Jiang, James Howard
Publikováno v:
Sunday, April 23.
Autor:
Jon P. Fryzek, Catherine Broome, Xiaohui Jiang, Megan Mullins, Lauren C. Bylsma, Adam Rosenthal, Julia M Cunningham
Publikováno v:
Research and Practice in Thrombosis and Haemostasis
Research and Practice in Thrombosis and Haemostasis, Vol 4, Iss 4, Pp 628-635 (2020)
Research and Practice in Thrombosis and Haemostasis, Vol 4, Iss 4, Pp 628-635 (2020)
Background Cold agglutinin disease (CAD) is a rare autoimmune hemolytic anemia mediated by IgM autoantibodies that trigger hemolysis via classical complement pathway. Increased incidence of thrombotic events (TEs) has been reported in patients with o
Autor:
Ruth Biehl, Anna Yu, Mary A. Kelly, Zartash Gul, Joan C. Pehta, Robertson D. Davenport, Jose A. Cancelas, Shawnagay Nestheide, Glen Michael Fitzpatrick, Catherine Broome, Zbigniew M. Szczepiorkowski, Bridget Kinne, Neeta Rugg, Ben Antebi, Hagop M. Kantarjian, Maro Ohanian, Vinod Pullarkat, Tor Hervig, Kelly Marek, Fleur M. Aung
Publikováno v:
American journal of hematologyREFERENCES. 97(3)
Thrombosomes are trehalose-stabilized, freeze-dried group O platelets with a 3-year shelf life. They can be stockpiled, rapidly reconstituted, and infused regardless of the recipient's blood type. Thrombosomes thus represent a potential alternative p
Autor:
Jaime Morales Arias, Parija Patel, Alexander Röth, Catherine Broome, Jun Su, Heidi Reichert, Jon P. Fryzek, Xiaohui Jiang
Publikováno v:
TransfusionREFERENCES. 62(1)
Background: Cold agglutinin disease (CAD) is a rare autoimmune hemolytic anemia mediated by immunoglobulin M autoantibodies that bind to the “I” antigen on erythrocytes. IgM binding results in either agglutination at ≤37°C, activation of the c
Autor:
Yoshitaka Miyakawa, Bernd Jilma, Shirley D'Sa, Catherine Broome, Xiaoyu Jiang, Tor Henrik Anderson Tvedt, Joachim Fruebis, Wilma Barcellini, Stella Lin, Alexander Röth, Sigbjørn Berentsen, Jaime Morales-Arias, David J. Kuter, Marc Michel, Caroline Reuter, William Hobbs
Publikováno v:
The New England journal of medicine. 384(14)
Cold agglutinin disease is a rare autoimmune hemolytic anemia characterized by hemolysis that is caused by activation of the classic complement pathway. Sutimlimab, a humanized monoclonal antibody, selectively targets the C1s protein, a C1 complex se
Autor:
Christopher J. Patriquin, Katerina Pavenski, Jocelyn S. Garland, Philip A. McFarlane, Dana Baran, Anne-Laure Lapeyraque, Catherine Broome, Christoph Licht, Martin Bitzan, Kuljit Grewal, Louis-Philippe Girard
Publikováno v:
Canadian Journal of Kidney Health and Disease
Canadian Journal of Kidney Health and Disease, Vol 8 (2021)
Canadian Journal of Kidney Health and Disease, Vol 8 (2021)
Thrombotic microangiopathy (TMA) is suspected in patients presenting with thrombocytopenia and evidence of a microangiopathic hemolytic anemia. Patients with TMA can be critically ill, so rapid and accurate identification of the underlying etiology i
Autor:
Marc Michel, Alexander Röth, Quentin A. Hill, Sigbjørn Berentsen, Wilma Barcellini, Catherine Broome, David J. Kuter, Marco Montillo, Morie A. Gertz, Ulrich Jäger, Sacha Zeerleder, Bernd Jilma, Anita Hill
Autoimmune hemolytic anemias (AIHAs) are rare and heterogeneous disorders characterized by the destruction of red blood cells through warm or cold antibodies. There is currently no licensed treatment for AIHA. Due to the paucity of clinical trials, r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7eb071aa0af0247f4c7b5be60df54c9b
Autor:
Bernd Jilma, Masaki Yamaguchi, Marek Wardecki, Ilene C. Weitz, Junichi Nishimura, Frank E. Shafer, Michelle A. Lee, Sigbjørn Berentsen, Deepthi Vagge, Marc Michel, Wilma Barcellini, Josephine M.I. Vos, Parija Patel, Shirley D'Sa, Braydon Schaible, Catherine Broome, Alexander Roeth, Xiaoyu Jiang, Nancy Wong, Michael J. Storek
Publikováno v:
Blood. 138:349-349
Background: CAD is a rare autoimmune hemolytic anemia mediated by classical complement pathway activation. Sutimlimab, a first-in-class humanized monoclonal anti-C1s IgG antibody, selectively inhibited the classical pathway, halted hemolysis, and imp