Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Catherine Bourdon"'
Autor:
Maria J. Garcia-Leon, Cristina Liboni, Vincent Mittelheisser, Louis Bochler, Gautier Follain, Clarisse Mouriaux, Ignacio Busnelli, Annabel Larnicol, Florent Colin, Marina Peralta, Naël Osmani, Valentin Gensbittel, Catherine Bourdon, Rafael Samaniego, Angélique Pichot, Nicodème Paul, Anne Molitor, Raphaël Carapito, Martine Jandrot-Perrus, Olivier Lefebvre, Pierre H. Mangin, Jacky G. Goetz
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-19 (2024)
Abstract Despite abundant evidence demonstrating that platelets foster metastasis, anti-platelet agents have low therapeutic potential due to the risk of hemorrhages. In addition, whether platelets can regulate metastasis at the late stages of the di
Externí odkaz:
https://doaj.org/article/2da522b6db60448cb066c2604318bcd1
Autor:
Alicia Aguilar, Josiane Weber, Julie Boscher, Monique Freund, Catherine Ziessel, Anita Eckly, Stéphanie Magnenat, Catherine Bourdon, Béatrice Hechler, Pierre H. Mangin, Christian Gachet, François Lanza, Catherine Léon
Publikováno v:
Blood Advances, Vol 3, Iss 15, Pp 2368-2380 (2019)
Abstract: The biogenesis of lysosome related organelles is defective in Hermansky-Pudlak syndrome (HPS), a disorder characterized by oculocutaneous albinism and platelet dense granule (DG) defects. The first animal model of HPS was the fawn-hooded ra
Externí odkaz:
https://doaj.org/article/f9d29b63529c4e02b39d934bab4263b3
Autor:
Cécile Loubière, Emily Janus-Bell, Cyril Scandola, Ahmed Muhammad-Usman, Alexandra A. Yakusheva, Clarisse Mouriaux, Pierre Mangin, Nicolas Receveur, Anita Eckly, Christian Gachet, Mikhail A. Panteleev, Yotis A. Senis, Catherine Bourdon
Publikováno v:
Thrombosis and Haemostasis. 122:767-776
Objective Integrins are key regulators of various platelet functions. The pathophysiological importance of most platelet integrins has been investigated, with the exception of α5β1, a receptor for fibronectin. The aim of this study was to character
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9135a5ea67491b59bdda9fd5a7f131b8
https://doi.org/10.1055/a-1659-6214
https://doi.org/10.1055/a-1659-6214
Autor:
Maria J. Garcia-Leon, Olivier Lefebvre, Gautier Follain, Clarisse Mouriaux, Ignacio Busnelli, Annabel Larnicol, Florent Colin, Vincent Mittelheisser, Marina Peralta, Catherine Bourdon, Raphael Samaniego, Martine Jandrot-Perrus, Pierre H. Mangin, Jacky G. Goetz
Despite abundant evidence demonstrating that platelets foster metastasis, a therapeutic approach based on anti-platelet agents is not an option due to the risk of hemorrhages. In addition, whether platelets can regulate metastasis at the late stages
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ce57f7d95329862b676cf4d1cd61b48b
https://doi.org/10.1101/2022.10.28.514195
https://doi.org/10.1101/2022.10.28.514195
Autor:
Anne Bonnin, Arvind Arun Dev, J. M. D. Coey, Bernard Doudin, Pierre Mangin, Lucas Giacchetti, Peter Dunne, Takuji Adachi, Alessandro Sorrenti, Thomas M. Hermans, Catherine Bourdon
Publikováno v:
Nature, Vol. 581, No 7806 (2020) pp. 58-62
Nature
Nature, 2020, 581 (7806), pp.58-62. ⟨10.1038/s41586-020-2254-4⟩
Nature
Nature, 2020, 581 (7806), pp.58-62. ⟨10.1038/s41586-020-2254-4⟩
When miniaturizing fluidic circuitry, the solid walls of the fluid channels become increasingly important(1) because they limit the flow rates achievable for a given pressure drop, and they are prone to fouling(2). Approaches for reducing the wall in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b979da0a3151dcc7f41d8f598180d3b1
https://archive-ouverte.unige.ch/unige:140859
https://archive-ouverte.unige.ch/unige:140859
Autor:
Catherine Ziessel, Stéphanie Magnenat, Monique Freund, Pierre Mangin, François Lanza, Anita Eckly, Béatrice Hechler, Julie Boscher, Josiane Weber, Alicia Aguilar, Catherine Bourdon, Christian Gachet, Catherine Léon
Publikováno v:
Blood Advances
Blood Advances, The American Society of Hematology, 2019, 3 (15), pp.2368-2380. ⟨10.1182/bloodadvances.2019031286⟩
Blood Advances, The American Society of Hematology, 2019, 3 (15), pp.2368-2380. ⟨10.1182/bloodadvances.2019031286⟩
International audience; Contrary to rat platelets, mouse platelets express both RAB32 and RAB38 that play fully redundant roles for dense granule biogenesis. • Combined RAB32 and RAB38 deficiency mimics severe Hermansky-Pudlak syndrome with albinis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f141877a41889931235c98b6d2bbd60
https://hal.archives-ouvertes.fr/hal-03030677/document
https://hal.archives-ouvertes.fr/hal-03030677/document
Autor:
Anita Eckly, Catherine Bourdon, Christiane Arnold, ChaoJun Tang, Mathieu Schaff, Eric Maurer, Béatrice Hechler, Christian Gachet, Adèle De Arcangelis, Pierre Mangin, François Lanza, Cécile V. Denis, Nicolas Receveur, Olivier Lefebvre, Bernhard Nieswandt, Elisabeth Georges-Labouesse
Publikováno v:
Circulation. 128:541-552
Background— Laminins are major components of basement membranes, well located to interact with platelets upon vascular injury. Laminin-111 (α 1 β 1 γ 1 ) is known to support platelet adhesion but is absent from most blood vessels, which contain
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c454d69823c093a2fb80b5ada4bb120
https://doi.org/10.1161/circulationaha.112.000799
https://doi.org/10.1161/circulationaha.112.000799
Autor:
Anita Eckly, Nicolas Receveur, Béatrice Hechler, Pierre Mangin, Christian Gachet, Catherine Ravanat, ChaoJun Tang, François Lanza, Eric Maurer, Catherine Bourdon, Mathieu Schaff
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 33:1221-1229
Objective— The glycoprotein (GP) Ib-V-IX complex regulates the adhesion, activation, and procoagulant activity of platelets. We previously reported that RAM.1, a rat monoclonal antibody directed against the extracellular domain of mouse GPIbβ, dim
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::143584c3f0b4f992f714fe4bc9469539
https://doi.org/10.1161/atvbaha.112.301013
https://doi.org/10.1161/atvbaha.112.301013
Autor:
Pierre Mangin, Monique Freund, Gertaud Orend, Camille Brucker, Scott I. Abrams, Catherine Bourdon, Adèle De Arcangelis, Christian Gachet, Paola Zigrino, Elmina Mammadova-Bach
Publikováno v:
JCI Insight. 1
Metastatic dissemination of cancer cells, which accounts for 90% of cancer mortality, is the ultimate hallmark of malignancy. Growing evidence suggests that blood platelets have a predominant role in tumor metastasis; however, the molecular mechanism
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4afebd014705600f00657979448febfa
https://doi.org/10.1172/jci.insight.88245
https://doi.org/10.1172/jci.insight.88245
Autor:
Pierre Mangin, Catherine Bourdon, Mathieu Schaff, François Lanza, Philippe Ohlmann, Christian Gachet, Nicolas Receveur
Publikováno v:
Thrombosis and Haemostasis
Thrombosis and Haemostasis, Schattauer, 2012, 107 (4), pp.735-48. ⟨10.1160/TH11-06-0430⟩
Thrombosis and Haemostasis, Schattauer, 2012, 107 (4), pp.735-48. ⟨10.1160/TH11-06-0430⟩
Summaryβ-arrestin-1 (β-arr1) and β-arrestin-2 (β-arr2) are cytosolic proteins well-known to participate in G protein-coupled receptor desensitisation and signalling. We used genetically-inactivated mice to evaluate the role of β-arr1 or β-arr2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31ab7ac665e307244a8eb62394199abf
https://doi.org/10.1160/th11-06-0430
https://doi.org/10.1160/th11-06-0430