Supplementary Figure Legends 1-3 from Integrin α5β1 Plays a Critical Role in Resistance to Temozolomide by Interfering with the p53 Pathway in High-Grade Glioma

Autor: Monique Dontenwill, Jan Teisinger, Sophie Martin, Julien Godet, Jacqueline Lehmann-Che, Natacha Entz-Werle, François Plenat, Pascal Chastagner, Sophie Pinel, Dominique Guenot, Eric Guerin, Fanny Noulet, Catherine Bossert, David Y. Leger, Anne Maglott, Hana Janouskova

PDF file - 85K

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::51378a6af35db20b7d5fcf7f4e14ed00
https://doi.org/10.1158/0008-5472.22391547.v1

Supplementary Figure 2 from Integrin α5β1 Plays a Critical Role in Resistance to Temozolomide by Interfering with the p53 Pathway in High-Grade Glioma

Autor: Monique Dontenwill, Jan Teisinger, Sophie Martin, Julien Godet, Jacqueline Lehmann-Che, Natacha Entz-Werle, François Plenat, Pascal Chastagner, Sophie Pinel, Dominique Guenot, Eric Guerin, Fanny Noulet, Catherine Bossert, David Y. Leger, Anne Maglott, Hana Janouskova

PDF file - 48K, Nutlin-3a decreases the total expression of Beta1 integrin subunit in U87MG cells but not its expression at the cell membrane

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc9951310e80493f76a8a068d8767b4e
https://doi.org/10.1158/0008-5472.22391553

Supplementary Table 3 from Integrin α5β1 Plays a Critical Role in Resistance to Temozolomide by Interfering with the p53 Pathway in High-Grade Glioma

Autor: Monique Dontenwill, Jan Teisinger, Sophie Martin, Julien Godet, Jacqueline Lehmann-Che, Natacha Entz-Werle, François Plenat, Pascal Chastagner, Sophie Pinel, Dominique Guenot, Eric Guerin, Fanny Noulet, Catherine Bossert, David Y. Leger, Anne Maglott, Hana Janouskova

PDF file - 27K, Relationship between Alpha5 mRNA level and p53 status in human biopsies and in human xenografts in nude mice

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c268f3214ec4ac68c520d6d915d74c6
https://doi.org/10.1158/0008-5472.22391538

Integrin α5β1 plays a critical role in resistance to temozolomide by interfering with the p53 pathway in high-grade glioma

Autor: Jacqueline Lehmann-Che, Pascal Chastagner, Hana Janouskova, Catherine Bossert, Sophie Martin, Jan Teisinger, Dominique Guenot, Eric Guérin, Anne Maglott, David Y. Leger, Sophie Pinel, Fanny Noulet, François Plénat, Julien Godet, Monique Dontenwill, Natacha Entz-Werle

Publikováno v: Cancer Research
Cancer Research, American Association for Cancer Research, 2012, 72 (14), pp.3463-3470. ⟨10.1158/0008-5472.CAN-11-4199⟩

Integrins play a role in the resistance of advanced cancers to radiotherapy and chemotherapy. In this study, we show that high expression of the α5 integrin subunit compromises temozolomide-induced tumor suppressor p53 activity in human glioblastoma

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a8dd3a4f2607d8802db755053662fbd
https://hal.archives-ouvertes.fr/hal-00746868