Phylogenetic inference of the emergence of sequence modules and protein-protein interactions in the ADAMTS-TSL family.

Autor: Olivier Dennler, François Coste, Samuel Blanquart, Catherine Belleannée, Nathalie Théret

Publikováno v: PLoS Computational Biology, Vol 19, Iss 8, p e1011404 (2023)

Numerous computational methods based on sequences or structures have been developed for the characterization of protein function, but they are still unsatisfactory to deal with the multiple functions of multi-domain protein families. Here we propose

Externí odkaz: https://doaj.org/article/9c1a1b04859040578efcd3e7f2373bb1

Two repeated motifs enriched within some enhancers and origins of replication are bound by SETMAR isoforms in human colon cells

Autor: Yves Bigot, Thierry Lecomte, Ahmed Arnaoty, Isabelle Stévant, Peter Arensburger, Vincent Coustham, Aymeric Antoine-Lorquin, Martine Batailler, Laura Helou, Serge Guyétant, Nicolas Buisine, Bruno Pitard, Sassan Asgari, Linda Beauclair, Catherine Belleannée

Publikováno v: Genomics
Genomics, Elsevier, 2021, 113 (3), pp.1589-1604. ⟨10.1016/j.ygeno.2021.03.032⟩
Genomics, 2021, 113 (3), pp.1589-1604. ⟨10.1016/j.ygeno.2021.03.032⟩

International audience; Setmar is a gene specific to simian genomes. The function(s) of its isoforms are poorly understood and their existence in healthy tissues remains to be validated. Here we profiled SETMAR expression and its genome-wide binding

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28d23d61fed90ab9656c31a4485712a7
https://hal.archives-ouvertes.fr/hal-03385429

Logol: Expressive Pattern Matching in Sequences. Application to Ribosomal Frameshift Modeling

Autor: Catherine Belleannée, Jacques Nicolas, Olivier Sallou

Publikováno v: Pattern Recognition in Bioinformatics ISBN: 9783319091914
PRIB
PRIB2014-Pattern Recognition in Bioinformatics, 9th IAPR International Conference
PRIB2014-Pattern Recognition in Bioinformatics, 9th IAPR International Conference, Lukas KALL, Aug 2014, Stockholm, Sweden. pp.34-47, ⟨10.1007/978-3-319-09192-1_4⟩

Most of the current practice of pattern matching tools is oriented towards finding efficient ways to compare sequences. This is useful but insufficient: as the knowledge and understanding of some functional or structural aspects of living systems imp

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0cf9ea0fdce4aa5b0bc91184a32f4a5
https://doi.org/10.1007/978-3-319-09192-1_4

Comparer des structures de gènes pour la prédiction de transcrits alternatifs codants chez l'humain, la souris et le chien

Autor: Guillaudeux, Nicolas

Publikováno v: Autre [cs.OH]. Université Rennes 1, 2021. Français. ⟨NNT : 2021REN1S079⟩

Living organisms are capable of expressing several alternative transcripts (or RNAs) from a single gene. These transcripts are responsible for the regulatory mechanisms of the organism, some of them are translated into protein. Today, detecting the s

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::d8df11a4ff30a8f0a752725dbcd7b953
https://theses.hal.science/tel-03593091v2/document

Caractérisation en modules fonctionnels de la famille de protéines ADAMTS / ADAMTSL

Autor: Dennler, Olivier

Publikováno v: Bio-informatique [q-bio.QM]. 2019

International audience

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::e51303f5b5f0be4d9aba5e374346fd23
https://hal.inria.fr/hal-02403084