Time-Dependent Decay of mRNA and Ribosomal RNA during Platelet Aging and Its Correlation with Translation Activity.

Autor: Catherine Angénieux, Blandine Maître, Anita Eckly, François Lanza, Christian Gachet, Henri de la Salle

Publikováno v: PLoS ONE, Vol 11, Iss 1, p e0148064 (2016)

Previous investigations have indicated that RNAs are mostly present in the minor population of the youngest platelets, whereas translation in platelets could be biologically important. To attempt to solve this paradox, we studied changes in the RNA c

Externí odkaz: https://doaj.org/article/83160c48db74410eaf9bec997c2bbcc0

Lysosomal-associated transmembrane protein 5 (LAPTM5) is a molecular partner of CD1e.

Autor: Catherine Angénieux, François Waharte, Alexandre Gidon, François Signorino-Gelo, Virginie Wurtz, Rim Hojeij, Fabienne Proamer, Christian Gachet, Alain Van Dorsselaer, Daniel Hanau, Jean Salamero, Henri de la Salle

Publikováno v: PLoS ONE, Vol 7, Iss 8, p e42634 (2012)

The CD1e protein participates in the presentation of lipid antigens in dendritic cells. Its transmembrane precursor is transported to lysosomes where it is cleaved into an active soluble form. In the presence of bafilomycin, which inhibits vacuolar A

Externí odkaz: https://doaj.org/article/0f6eb4275f1744379cfb094124192b92

Discriminating young platelets on human leukocyte antigen-I expression highlights their extremely high reactivity potential

Autor: Catherine Angénieux, Adèle Couvidou, Nathalie Brouard, Anita Eckly, Arnaud Dupuis, Pierre H. Mangin, Blandine Maître

Publikováno v: Research and Practice in Thrombosis and Haemostasis. 7:100006

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::4e35ec46d9ff718d2397e79d2d9b158f
https://doi.org/10.1016/j.rpth.2022.100006

Cell surface expression of HLA I molecules as a marker of young platelets

Autor: Catherine Angénieux, Arnaud Dupuis, Christian Gachet, Henri de la Salle, Blandine Maître

Publikováno v: Journal of thrombosis and haemostasis : JTHREFERENCES. 17(9)

Background Accurate identification of the proportion of young platelets is important to distinguish peripheral thrombocytopenia from a deficit in platelet production. Young platelets are defined by their higher RNA content and are often assessed as t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b0c2827501a825f61cd4b1b19f822902
https://pubmed.ncbi.nlm.nih.gov/31207003

Fine tuning by human CD1e of lipid-specific immune responses

Autor: Gennaro De Libero, Lena Angman, Luigi Panza, Catherine Angénieux, Giulia Casorati, Steven A. Porcelli, Marco Cavallari, Paolo Dellabona, François Signorino-Gelo, Chengfeng Xia, Jacques Prandi, Luis F. Garcia-Alles, Germain Puzo, Martine Gilleron, Federica Facciotti, Peng George Wang, Lucia Mori

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America
Proceedings of the National Academy of Sciences of the United States of America, National Academy of Sciences, 2011, 108 (34), pp.14228-14233. ⟨10.1073/pnas.1108809108⟩
Proceedings of the National Academy of Sciences of the United States of America, 2011, 108 (34), pp.14228-14233. ⟨10.1073/pnas.1108809108⟩
Proceedings of the National Academy of Sciences; Vol 108
Proceedings of the National Academy of Sciences

CD1e is a member of the CD1 family that participates in lipid antigen presentation without interacting with the T-cell receptor. It binds lipids in lysosomes and facilitates processing of complex glycolipids, thus promoting editing of lipid antigens.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d8770b7a830ee4f4cd21a9d09f20752f
https://doi.org/10.1073/pnas.1108809108