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Autor:
Capucine Picard, Jocelyn Vedrenne, Magda Dziembowska, Dominique Charron, Marie-Claude Fondanèche, Andrew J. Cant, Alain Fischer, Wojciech Wiszniewski, Viktor Steimle, Giovanna Barbieri, Catherine Alca-Loridan, B. Lisowska-Grospierre
Publikováno v:
Immunogenetics. 53:821-829
Four transacting genes, CIITA, RFXANK, RFX5, and RFXAP, control coordinate MHC II expression. In humans, defects in these genes result in the absence of MHC II expression and thus a combined immunodeficiency. CIITA is considered to be a master MHC II