Zobrazeno 1 - 10
of 234
pro vyhledávání: '"Catherine A. Reardon"'
Autor:
Godfrey S. Getz, Catherine A. Reardon
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 12, p 6375 (2024)
Atherosclerosis is an inflammatory reaction that develops at specific regions within the artery wall and at specific sites of the arterial tree over a varying time frame in response to a variety of risk factors. The mechanisms that account for the in
Externí odkaz:
https://doaj.org/article/cec8e1649fc2468f89503ab8411f98a8
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 8 (2021)
Externí odkaz:
https://doaj.org/article/faebca1554664e4a8b901161dbd979fd
Autor:
Brittney R. Coats, Kelly Q. Schoenfelt, Valéria C. Barbosa-Lorenzi, Eduard Peris, Chang Cui, Alexandria Hoffman, Guolin Zhou, Sully Fernandez, Lijie Zhai, Ben A. Hall, Abigail S. Haka, Ajay M. Shah, Catherine A. Reardon, Matthew J. Brady, Christopher J. Rhodes, Frederick R. Maxfield, Lev Becker
Publikováno v:
Cell Reports, Vol 20, Iss 13, Pp 3149-3161 (2017)
During obesity, adipose tissue macrophages (ATMs) adopt a metabolically activated (MMe) phenotype. However, the functions of MMe macrophages are poorly understood. Here, we combine proteomic and functional methods to demonstrate that, in addition to
Externí odkaz:
https://doaj.org/article/9dd7d9447f5a4879beccbb036e888af5
Autor:
Godfrey S. Getz, Catherine A. Reardon
Publikováno v:
Frontiers in Pharmacology, Vol 10 (2019)
Macrophages are core cellular elements of both early and advanced atherosclerosis. They take up modified lipoproteins and become lipid-loaded foam cells and secrete factors that influence other cell types in the artery wall involved in atherogenesis.
Externí odkaz:
https://doaj.org/article/66a545c911c14e599ef36a63931452e1
Autor:
Godfrey S. Getz, Catherine A. Reardon
Publikováno v:
Journal of Lipid Research, Vol 57, Iss 5, Pp 758-766 (2016)
ApoE is a multifunctional protein that is expressed by many cell types that influences many aspects of cardiovascular physiology. In humans, there are three major allelic variants that differentially influence lipoprotein metabolism and risk for the
Externí odkaz:
https://doaj.org/article/031c09eb5f1842d1af6eecc3ba80952b
Autor:
Nathalie Pamir, Patrick Hutchins, Graziella Ronsein, Tomas Vaisar, Catherine A. Reardon, Godfrey S. Getz, Aldons J. Lusis, Jay W. Heinecke
Publikováno v:
Journal of Lipid Research, Vol 57, Iss 2, Pp 246-257 (2016)
Cholesterol efflux capacity associates strongly and negatively with the incidence and prevalence of human CVD. We investigated the relationships of HDL's size and protein cargo with its cholesterol efflux capacity using APOB-depleted serum and HDLs i
Externí odkaz:
https://doaj.org/article/0ddc1206bf254b4a932d318672fb83b5
Autor:
Tapan K. Biswas, Paul A. VanderLaan, Xuchu Que, Ayelet Gonen, Paulette Krishack, Christoph J. Binder, Joseph L. Witztum, Godfrey S. Getz, Catherine A. Reardon
Publikováno v:
Antibodies, Vol 9, Iss 3, p 30 (2020)
Natural antibodies (NAbs) are important regulators of tissue homeostasis and inflammation and are thought to have diverse protective roles in a variety of pathological states. E06 is a T15 idiotype IgM NAb exclusively produced by B-1 cells, which rec
Externí odkaz:
https://doaj.org/article/a63e5d9ba0bf4b0a9b3c18adfd39be96
Autor:
Paul A. VanderLaan, Catherine A. Reardon, Veneracion G. Cabana, Chyung-Ru Wang, Godfrey S. Getz
Publikováno v:
International Journal of Molecular Sciences, Vol 20, Iss 18, p 4566 (2019)
Natural killer T (NKT) cells are a distinct subset of lymphocytes that bridge the innate and adaptive immune response and can be divided into type I invariant NKT cells (iNKT) and type II NKT cells. The objective of this study is to examine the effec
Externí odkaz:
https://doaj.org/article/f0c3f044bd6249b582dbc2fc88e3b529
Autor:
Ibra S. Fancher, Sang Joon Ahn, Crystal Adamos, Catherine Osborn, Myung‐Jin Oh, Yun Fang, Catherine A. Reardon, Godfrey S. Getz, Shane A. Phillips, Irena Levitan
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 7, Iss 5 (2018)
BackgroundHypercholesterolemia‐induced decreased availability of nitric oxide (NO) is a major factor in cardiovascular disease. We previously established that cholesterol suppresses endothelial inwardly rectifying K+ (Kir) channels and that Kir2.1
Externí odkaz:
https://doaj.org/article/b25e5cddcfa94e2d976eaa15164a2f6a
Publikováno v:
Journal of Lipid Research, Vol 56, Iss 2, Pp 215-226 (2015)
apoE is a multi-functional protein expressed in several cell types and in several organs. It is highly expressed in adipose tissue, where it is important for modulating adipocyte lipid flux and gene expression in isolated adipocytes. In order to inve
Externí odkaz:
https://doaj.org/article/07a58f2dc25940de9a40ef6270a8fc9a