Zobrazeno 1 - 10
of 61
pro vyhledávání: '"Catherine A. Makarewich"'
Publikováno v:
iScience, Vol 26, Iss 6, Pp 106781- (2023)
Summary: Ongoing efforts to generate a complete and accurate annotation of the genome have revealed a significant blind spot for small proteins (
Externí odkaz:
https://doaj.org/article/15a51f219e434dc8a7ae5221b6c39cee
Autor:
Emily D. Morales, Yongping Yue, Thais B. Watkins, Jin Han, Xiufang Pan, Aaron M. Gibson, Bryan Hu, Omar Brito‐Estrada, Gang Yao, Catherine A. Makarewich, Gopal J. Babu, Dongsheng Duan
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 12, Iss 3 (2023)
Background Cardiomyopathy is a leading health threat in Duchenne muscular dystrophy (DMD). Cytosolic calcium upregulation is implicated in DMD cardiomyopathy. Calcium is primarily removed from the cytosol by the sarcoendoplasmic reticulum calcium ATP
Externí odkaz:
https://doaj.org/article/9a37d2fd69cd4921bac7c1d3539ed8f5
Autor:
Catherine A. Makarewich, Kedryn K. Baskin, Amir Z. Munir, Svetlana Bezprozvannaya, Gaurav Sharma, Chalermchai Khemtong, Akansha M. Shah, John R. McAnally, Craig R. Malloy, Luke I. Szweda, Rhonda Bassel-Duby, Eric N. Olson
Publikováno v:
Cell Reports, Vol 23, Iss 13, Pp 3701-3709 (2018)
Summary: Micropeptide regulator of β-oxidation (MOXI) is a conserved muscle-enriched protein encoded by an RNA transcript misannotated as non-coding. MOXI localizes to the inner mitochondrial membrane where it associates with the mitochondrial trifu
Externí odkaz:
https://doaj.org/article/7104ce443c914948b23d40e5e3e40066
Autor:
Catherine A Makarewich, Amir Z Munir, Gabriele G Schiattarella, Svetlana Bezprozvannaya, Olga N Raguimova, Ellen E Cho, Alexander H Vidal, Seth L Robia, Rhonda Bassel-Duby, Eric N Olson
Publikováno v:
eLife, Vol 7 (2018)
Calcium (Ca2+) dysregulation is a hallmark of heart failure and is characterized by impaired Ca2+ sequestration into the sarcoplasmic reticulum (SR) by the SR-Ca2+-ATPase (SERCA). We recently discovered a micropeptide named DWORF (DWarf Open Reading
Externí odkaz:
https://doaj.org/article/17910729edca42d2bb94d6b5f26cec6c
Autor:
Zegeye Hailu Jebessa, Andrea Schneider, Matthias Dewenter, Michael Berlin, Catherine A Makarewich, Eric N Olson, Marc Freichel, Martin Busch, Johannes Backs, Patrick Most
Publikováno v:
Circulation Research. 131
Background & Objectives: SR Ca2+ load, which is sustained by SERCA2a pump activity, is a critical determinant for cardiac performance regulation & adaptation. Independent studies identified both S100A1 & STRIT1 as molecular enhancers of SERCA2a activ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0ce560a0284b51d55d14aa1ef21d6091
https://doi.org/10.1161/res.131.suppl_1.p2006
https://doi.org/10.1161/res.131.suppl_1.p2006
Publikováno v:
Circulation Research. 131
Although they were originally misclassified as lncRNAs due to oversights in genome annotation methods, microproteins—proteins with open reading frames (ORFs) of 150 amino acids or less—execute critical roles in heart and skeletal muscle. We have
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::664f4c33cb63276048c1fd1a919ef786
https://doi.org/10.1161/res.131.suppl_1.p2009
https://doi.org/10.1161/res.131.suppl_1.p2009
Autor:
Deo R. Singh, Michael P. Dalton, Eric N. Olson, Catherine A. Makarewich, Seth L. Robia, Marsha P. Pribadi, Jaroslava Seflova, Ellen E. Cho, Taylor J. Zak
Publikováno v:
J Mol Biol
The recently-discovered single-span transmembrane proteins endoregulin (ELN), dwarf open reading frame (DWORF), myoregulin (MLN), and another-regulin (ALN) are reported to bind to the SERCA calcium pump in a manner similar to that of known regulators
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a494dd7955e39ed8bb91a89316d25a5
https://doi.org/10.1016/j.jmb.2019.07.037
https://doi.org/10.1016/j.jmb.2019.07.037
Autor:
Catherine A. Makarewich, Rhonda Bassel-Duby, John R. McAnally, Svetlana Bezprozvannaya, Thomas P Matthews, Sean J. Morrison, Eric N. Olson, Misty Martin, Amir Z Munir, Aaron M. Gibson
Publikováno v:
Circulation. 142
Introduction: Emerging evidence suggests that many RNA molecules currently annotated as noncoding contain short open reading frames that code for functional small proteins called microproteins. Microproteins play critical roles in a diverse range of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::784e26504eea5d4d989de15afc92aad0
https://doi.org/10.1161/circ.142.suppl_3.16602
https://doi.org/10.1161/circ.142.suppl_3.16602
Autor:
Catherine A. Makarewich
Publikováno v:
Exp Cell Res
Proteins are critical components of biological membranes and play key roles in many essential cellular processes. Membrane proteins are a structurally and functionally diverse family of proteins that have recently expanded to include a number of newl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::faa1fdabe6fe1c8bb8987b879b97253b
https://europepmc.org/articles/PMC7050383/
https://europepmc.org/articles/PMC7050383/
