Zobrazeno 1 - 10
of 185
pro vyhledávání: '"Catherine A. Chen"'
Autor:
Anjali A. Dixit, Nhi Ho, Christina Inglis-Arkell, Catherine L. Chen, Marla Ferschl, Solmaz P. Manuel
Publikováno v:
Annals of Pediatric Surgery, Vol 18, Iss 1, Pp 1-8 (2022)
Abstract Background Surgery is a risk factor for opioid initiation, persistent use, and subsequent misuse in pediatric patients. The objective of this study was to assess the rate of postoperative opioid prescribing and extent of unused opioid prescr
Externí odkaz:
https://doaj.org/article/4bc01748872042478ce01c01a9b3f94c
Autor:
Qi Zhang, Peter Radvak, Juhyung Lee, Yue Xu, Vivian Cao-Dao, Miao Xu, Wei Zheng, Catherine Z. Chen, Hang Xie, Yihong Ye
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-12 (2022)
Abstract Spike-mediated entry of SARS-CoV-2 into human airway epithelial cells is an attractive therapeutic target for COVID-19. In addition to protein receptors, the SARS-CoV-2 spike (S) protein also interacts with heparan sulfate, a negatively char
Externí odkaz:
https://doaj.org/article/b7d78836b1ae4c59b03c59764d31d12c
Autor:
Miao Xu, Manisha Pradhan, Kirill Gorshkov, Jennifer D. Petersen, Min Shen, Hui Guo, Wei Zhu, Carleen Klumpp-Thomas, Sam Michael, Misha Itkin, Zina Itkin, Marco R. Straus, Joshua Zimmerberg, Wei Zheng, Gary R. Whittaker, Catherine Z. Chen
Publikováno v:
SLAS Discovery, Vol 27, Iss 2, Pp 86-94 (2022)
Effective small molecule therapies to combat the SARS-CoV-2 infection are still lacking as the COVID-19 pandemic continues globally. High throughput screening assays are needed for lead discovery and optimization of small molecule SARS-CoV-2 inhibito
Externí odkaz:
https://doaj.org/article/f90b163e74134d30a8498c4857c338e0
Autor:
Erica Langnas, Rosa Rodriguez-Monguio, Yanting Luo, Rhiannon Croci, R. Adams Dudley, Catherine L. Chen
Publikováno v:
Perioperative Medicine, Vol 10, Iss 1, Pp 1-10 (2021)
Abstract Background Opioids and multimodal analgesia are widely administered to manage postoperative pain. However, little is known on how improvements in inpatient pain control are correlated with high-risk (> 90 daily OME) discharge opioid prescrip
Externí odkaz:
https://doaj.org/article/5b5b8ba93d044314b66d4c13fd4f2e5a
Autor:
Stephanie Jensen, Catherine J. Chen
Publikováno v:
Urology Case Reports, Vol 45, Iss , Pp 102274- (2022)
A small subset of males presenting with cryptorchidism are found to have ectopic testes. The most common location for an ectopic testicle is the superficial inguinal pouch, but there are several other possibilities, necessitating a thorough physical
Externí odkaz:
https://doaj.org/article/acd96d38701148bcaf55ad080e026809
Autor:
Hu Zhu, Catherine Z. Chen, Srilatha Sakamuru, Jinghua Zhao, Deborah K. Ngan, Anton Simeonov, Mathew D. Hall, Menghang Xia, Wei Zheng, Ruili Huang
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
Abstract The recent global pandemic of the Coronavirus disease 2019 (COVID-19) caused by the new coronavirus SARS-CoV-2 presents an urgent need for the development of new therapeutic candidates. Many efforts have been devoted to screening existing dr
Externí odkaz:
https://doaj.org/article/1a6ca3565e3544ed8363995ed6f8f3f9
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Tay-Sachs disease (TSD) is an autosomal recessive disease that features progressive neurodegenerative presentations. It affects one in 100,000 live births. Currently, there is no approved therapy or cure. This review summarizes multiple drug developm
Externí odkaz:
https://doaj.org/article/3635182fa85b4adfa256c46abccea0e5
Autor:
Ying Fu, Juliana da Fonseca Rezende E Mello, Bryan D Fleming, Alex Renn, Catherine Z Chen, Xin Hu, Miao Xu, Kirill Gorshkov, Quinlin Hanson, Wei Zheng, Emily M Lee, Lalith Perera, Robert Petrovich, Manisha Pradhan, Richard T Eastman, Zina Itkin, Thomas B Stanley, Allen Hsu, Venkata Dandey, Kedar Sharma, William Gillette, Troy Taylor, Nitya Ramakrishnan, Shelley Perkins, Dominic Esposito, Eunkeu Oh, Kimihiro Susumu, Mason Wolak, Marc Ferrer, Matthew D Hall, Mario J Borgnia, Anton Simeonov
Publikováno v:
PLoS ONE, Vol 17, Iss 8, p e0272364 (2022)
Neutralizing antibodies targeting the SARS-CoV-2 spike protein have shown a great preventative/therapeutic potential. Here, we report a rapid and efficient strategy for the development and design of SARS-CoV-2 neutralizing humanized nanobody construc
Externí odkaz:
https://doaj.org/article/f2f1ebb6cd9a4991a32d3546fa2987d7
Autor:
Shengbiao Zhang, Peijun Hou, Jiyun Kang, Tianyi Li, Shahryar Mooraj, Yang Ren, Catherine H. Chen, A. John Hart, Simos Gerasimidis, Wen Chen
Publikováno v:
Journal of Materials Science & Technology. 154:149-158
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::edfdbd42dbdb177e45541a6ecdea1270
https://doi.org/10.1016/j.jmst.2023.01.018
https://doi.org/10.1016/j.jmst.2023.01.018
Autor:
Brianna M. Brooks, Manisha Pradhan, Yu-Shan Cheng, Kirill Gorshkov, Atena Farkhondeh, Catherine Z. Chen, Jeanette Beers, Chengyu Liu, Karsten Baumgaertel, Steven Rodems, Wei Zheng
Publikováno v:
Stem Cell Research, Vol 54, Iss , Pp 102447- (2021)
Alagille syndrome (ALGS) is a rare autosomal dominant disorder caused by disruption of the Notch signaling pathway due to mutations in either JAGGED1 (JAG1) (ALGS type 1) or NOTCH2 (ALGS type 2). Loss of this signaling interferes with the development
Externí odkaz:
https://doaj.org/article/2f12baeebb87454e85e831c61b5e858d