Zobrazeno 1 - 10
of 243
pro vyhledávání: '"Catherine A Harwood"'
Autor:
Serena Ramjee, Hanen Mohamedthani, Aditya Umeshkumar Patel, Rebeca Goiriz, Catherine A Harwood, Richard H Osborne, Christina Cheng, Zeeshaan-ul Hasan
Publikováno v:
JMIR Dermatology, Vol 6, p e48981 (2023)
BackgroundGiven the expansion of remote digital dermatology services from the National Health Service, particularly during the COVID-19 pandemic, there is a need for methods that identify patients at risk of digital exclusion to guide equitable repre
Externí odkaz:
https://doaj.org/article/270cae2c93b548b7ae23a062e2cbf86c
Autor:
Kevin Lai, Catherine A Harwood, Karin J Purdie, Charlotte M Proby, Irene M Leigh, Namita Ravi, Thaddeus W Mully, Lionel Brooks, Priscilla M Sandoval, Michael D Rosenblum, Sarah T Arron
Publikováno v:
PLoS ONE, Vol 12, Iss 11, p e0188272 (2017)
Atypical fibroxanthoma (AFX), is a rare type of skin cancer affecting older individuals with sun damaged skin. Since there is limited genomic information about AFX, our study seeks to improve the understanding of AFX through whole-exome and RNA seque
Externí odkaz:
https://doaj.org/article/e97ef3f1d0b9437da097400ec0d34427
Autor:
Edit B Olasz, Lauren N Seline, Ashley M Schock, Nathan E Duncan, Argelia Lopez, Jozef Lazar, Michael J Flister, Yan Lu, Pengyuan Liu, Olayemi Sokumbi, Catherine A Harwood, Charlotte M Proby, Marcy Neuburg, Zelmira Lazarova
Publikováno v:
PLoS ONE, Vol 10, Iss 5, p e0125412 (2015)
Cutaneous squamous cell carcinoma (cSCC) is the second most common skin malignancy and it presents a therapeutic challenge in organ transplant recipient patients. Despite the need, there are only a few targeted drug treatment options. Recent studies
Externí odkaz:
https://doaj.org/article/7bef06caea524d00b6520112dd9daa05
Autor:
Arucha L Ekeowa-Anderson, Karin J Purdie, Karen Gibbon, Carolyn R Byrne, Jeffrey M Arbeit, Catherine A Harwood, Ryan F L O'Shaughnessy
Publikováno v:
PLoS ONE, Vol 7, Iss 6, p e38608 (2012)
Anogenital malignancy has a significant association with high-risk mucosal alpha-human papillomaviruses (alpha-PV), particularly HPV 16 and 18 whereas extragenital SCC has been linked to the presence of cutaneous beta and gamma-HPV types. Vulval skin
Externí odkaz:
https://doaj.org/article/10fb38da83e8489d8c9864df59090379
Autor:
Peter Bailey, Rachel A. Ridgway, Patrizia Cammareri, Mairi Treanor-Taylor, Ulla-Maja Bailey, Christina Schoenherr, Max Bone, Daniel Schreyer, Karin Purdie, Jason Thomson, William Rickaby, Rene Jackstadt, Andrew D. Campbell, Emmanouil Dimonitsas, Alexander J. Stratigos, Sarah T. Arron, Jun Wang, Karen Blyth, Charlotte M. Proby, Catherine A. Harwood, Owen J. Sansom, Irene M. Leigh, Gareth J. Inman
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-14 (2023)
Abstract The molecular basis of disease progression from UV-induced precancerous actinic keratosis (AK) to malignant invasive cutaneous squamous cell carcinoma (cSCC) and potentially lethal metastatic disease remains unclear. DNA sequencing studies h
Externí odkaz:
https://doaj.org/article/12b4077a59444dd3949da320a9c0d1e9
Publikováno v:
Acta Dermato-Venereologica, Vol 103 (2023)
Abstract is missing Short communication
Externí odkaz:
https://doaj.org/article/b3d99570d7ec437d85c20ae7167db441
Autor:
Rachel Mary Fisher, Antonio Ji-Xu, Rachel Abbott, Tanya Basu, Alistair Brown, Catherine Foley, Catriona Glen, Girish Gupta, Zeeshaan Hasan, Ferina Ismail, Amina Khalid, Andre B. S. Khoo, Dimitra Koumaki, Aoife Lally, John T. Lear, Emily Jane McGrath, Kein McKenna, Alan Milligan, Orlagh Mulholland, Fiona Tasker, Catherine A. Harwood, Charlotte M. Proby, Rubeta N. Matin
Publikováno v:
Clinical and Experimental Dermatology. 47:1976-1981
Background Individuals with a prior diagnosis of chronic lymphocytic leukaemia (CLL) have a higher risk of developing melanoma and exhibit poorer outcomes than patients without CLL. However, there are limited data reporting the clinicopathological fe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f22f024777b02111ba03834dedae2d0
https://doi.org/10.1111/ced.15324
https://doi.org/10.1111/ced.15324
Autor:
Graham W. Neill, Mike P. Philpott, Kenneth J. Linton, David P. Kelsell, Ravinder Atkar, Muhammad S. Pirzado, Catherine A. Harwood, Dimalee S. Herath, Joanne L. Selway, Allon Hazan, Muhammad M. Rahman
[A] Various exon 24 clones generated from heterogeneous populations of PTCH1 suppressed NEB1 cells show reduced PTCH1 and increased GLI1 mRNA expression. [B] Both human and mouse SMO protein sequences contain predicted nuclear and nucleolar localisat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::60b044d18f7b24f0f78ee05c491128fa
https://doi.org/10.1158/0008-5472.22420313
https://doi.org/10.1158/0008-5472.22420313
Autor:
Daniele Bergamaschi, Catherine A. Harwood, Rubeta N. Matin, Christian Posch, Andrea Maurichi, Monica Rodolfo, Elisabetta Vergani, Giovanna Chiorino, Maria Scatolini, Tania Maffucci, Tiffanie-Marie Borg, Luke Gammon, Viviana Mannella, Lucia Fraile Garcia, Ankit Patel
Targeting the MAPK pathway by combined inhibition of BRAF and MEK has increased overall survival in advanced BRAF-mutant melanoma in both therapeutic and adjuvant clinical settings. However, a significant proportion of tumors develop acquired resista
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a7bd3b6ee6e425241bf7d6fa8e37e16
https://doi.org/10.1158/0008-5472.c.6511894.v1
https://doi.org/10.1158/0008-5472.c.6511894.v1
Autor:
Graham W. Neill, Mike P. Philpott, Kenneth J. Linton, David P. Kelsell, Ravinder Atkar, Muhammad S. Pirzado, Catherine A. Harwood, Dimalee S. Herath, Joanne L. Selway, Allon Hazan, Muhammad M. Rahman
Small-molecule inhibitors of the Hedgehog (HH) pathway receptor Smoothened (SMO) have been effective in treating some patients with basal cell carcinoma (BCC), where the HH pathway is often activated, but many patients respond poorly. In this study,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::843ce48a60ee1307e6d00253da450b72
https://doi.org/10.1158/0008-5472.c.6510620
https://doi.org/10.1158/0008-5472.c.6510620