Zobrazeno 1 - 10
of 104
pro vyhledávání: '"Catherine A Fox"'
Publikováno v:
PLoS Genetics, Vol 20, Iss 8, p e1011366 (2024)
In Saccharomyces cerevisiae, the forkhead (Fkh) transcription factor Fkh1 (forkhead homolog) enhances the activity of many DNA replication origins that act in early S-phase (early origins). Current models posit that Fkh1 acts directly to promote thes
Externí odkaz:
https://doaj.org/article/2360b81529ef4b71ad7488bf4d73cdf6
Autor:
Timothy A Hoggard, FuJung Chang, Kelsey Rae Perry, Sandya Subramanian, Jessica Kenworthy, Julie Chueng, Erika Shor, Edel M Hyland, Jef D Boeke, Michael Weinreich, Catherine A Fox
Publikováno v:
PLoS Genetics, Vol 14, Iss 5, p e1007418 (2018)
Most active DNA replication origins are found within euchromatin, while origins within heterochromatin are often inactive or inhibited. In yeast, origin activity within heterochromatin is negatively controlled by the histone H4K16 deacetylase, Sir2,
Externí odkaz:
https://doaj.org/article/8d599bf378214fdca25d45a07be1710b
Autor:
Antoinette M Dummer, Zhangli Su, Rachel Cherney, Koyi Choi, John Denu, Xiaolan Zhao, Catherine A Fox
Publikováno v:
PLoS Genetics, Vol 12, Iss 6, p e1006094 (2016)
The Saccharomyces cerevisiae Fkh1 protein has roles in cell-cycle regulated transcription as well as a transcription-independent role in recombination donor preference during mating-type switching. The conserved FHA domain of Fkh1 regulates donor pre
Externí odkaz:
https://doaj.org/article/bd7cfcda18e948fda28a37cea323afa3
Autor:
A Zachary Ostrow, Tittu Nellimoottil, Simon R V Knott, Catherine A Fox, Simon Tavaré, Oscar M Aparicio
Publikováno v:
PLoS ONE, Vol 9, Iss 2, p e87647 (2014)
Forkhead box (FOX) transcription factors regulate a wide variety of cellular functions in higher eukaryotes, including cell cycle control and developmental regulation. In Saccharomyces cerevisiae, Forkhead proteins Fkh1 and Fkh2 perform analogous fun
Externí odkaz:
https://doaj.org/article/f0dea4794ee94b31b24da3b547f311c2
Publikováno v:
PLoS Genetics, Vol 9, Iss 9, p e1003798 (2013)
Eukaryotic DNA replication origins are selected in G1-phase when the origin recognition complex (ORC) binds chromosomal positions and triggers molecular events culminating in the initiation of DNA replication (a.k.a. origin firing) during S-phase. Ea
Externí odkaz:
https://doaj.org/article/d39805776d0644a199ad3b44d503d8ad
Publikováno v:
PLoS Genetics, Vol 9, Iss 8, p e1003680 (2013)
Conditions of chronic stress are associated with genetic instability in many organisms, but the roles of stress responses in mutagenesis have so far been elucidated only in bacteria. Here, we present data demonstrating that the environmental stress r
Externí odkaz:
https://doaj.org/article/dc62c1acd02a4703ae13ebddd0e29b58
Autor:
Erika Shor, Christopher L Warren, Joshua Tietjen, Zhonggang Hou, Ulrika Müller, Ilaria Alborelli, Florence H Gohard, Adrian I Yemm, Lev Borisov, James R Broach, Michael Weinreich, Conrad A Nieduszynski, Aseem Z Ansari, Catherine A Fox
Publikováno v:
PLoS Genetics, Vol 5, Iss 12, p e1000755 (2009)
The origin recognition complex (ORC) marks chromosomal sites as replication origins and is essential for replication initiation. In yeast, ORC also binds to DNA elements called silencers, where its primary function is to recruit silent information re
Externí odkaz:
https://doaj.org/article/6789becc7c98478a9587243c67348fd3
Publikováno v:
Nucleic Acids Research
The pioneer event in eukaryotic DNA replication is binding of chromosomal DNA by the origin recognitioncomplex (ORC). The ORC-DNA complex directs the formation of origins, the specific chromosomal regions where DNA synthesis initiates. In all eukaryo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6724225acf6c0f148e558008010ccfcf
https://doi.org/10.1093/nar/gkab450
https://doi.org/10.1093/nar/gkab450
The Bicaudal-C (Bicc1) multi-KH domain RNA binding protein controls cell fates by binding and repressing the translation of specific target mRNAs. To provide new insights into Bicc1-RNA binding we used quantitative assays to analyze interactions betw
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6f0753e2b94b5758a1823193756ad84f
https://doi.org/10.1101/2022.07.22.501140
https://doi.org/10.1101/2022.07.22.501140
Autor:
Gemma Regan-Mochrie, Timothy Hoggard, Nikhil Bhagwat, Gerard Lynch, Neil Hunter, Dirk Remus, Catherine A. Fox, Xiaolan Zhao
Publikováno v:
Genes & development, vol 36, iss 13-14
Sumoylation is emerging as a posttranslation modification important for regulating chromosome duplication and stability. The origin recognition complex (ORC) that directs DNA replication initiation by loading the MCM replicative helicase onto origins
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af4575383268c7297c6f136c2282898c
https://pubmed.ncbi.nlm.nih.gov/35926881
https://pubmed.ncbi.nlm.nih.gov/35926881