Zobrazeno 1 - 10
of 58
pro vyhledávání: '"Catherine A A, Beauchemin"'
Autor:
Jamie Porthiyas, Daniel Nussey, Catherine A. A. Beauchemin, Donald C. Warren, Christian Quirouette, Kathleen P. Wilkie
Publikováno v:
npj Systems Biology and Applications, Vol 10, Iss 1, Pp 1-12 (2024)
Abstract Mechanistic mathematical models (MMs) are a powerful tool to help us understand and predict the dynamics of tumour growth under various conditions. In this work, we use 5 MMs with an increasing number of parameters to explore how certain (of
Externí odkaz:
https://doaj.org/article/f027652e83614f288dc0c0b840413978
Autor:
Christian Quirouette, Daniel Cresta, Jizhou Li, Kathleen P. Wilkie, Haozhao Liang, Catherine A. A. Beauchemin
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-32 (2023)
Abstract A virus infection can be initiated with very few or even a single infectious virion, and as such can become extinct, i.e. stochastically fail to take hold or spread significantly. There are many ways that a fully competent infectious virion,
Externí odkaz:
https://doaj.org/article/9f83d01d52c347c0bf5eb20edbd516d1
Autor:
Daniel Cresta, Donald C Warren, Christian Quirouette, Amanda P Smith, Lindey C Lane, Amber M Smith, Catherine A A Beauchemin
Publikováno v:
PLoS Computational Biology, Vol 19, Iss 1, p e1010877 (2023)
[This corrects the article DOI: 10.1371/journal.pcbi.1009480.].
Externí odkaz:
https://doaj.org/article/1ea084e9857c4e4183c3d48f660b6879
Publikováno v:
PLoS Computational Biology, Vol 18, Iss 2 (2022)
Externí odkaz:
https://doaj.org/article/d4c6492f7c014aecab9ead0eb8d945cd
Autor:
Daniel Cresta, Donald C Warren, Christian Quirouette, Amanda P Smith, Lindey C Lane, Amber M Smith, Catherine A A Beauchemin
Publikováno v:
PLoS Computational Biology, Vol 17, Iss 10, p e1009480 (2021)
The endpoint dilution assay's output, the 50% infectious dose (ID50), is calculated using the Reed-Muench or Spearman-Kärber mathematical approximations, which are biased and often miscalculated. We introduce a replacement for the ID50 that we call
Externí odkaz:
https://doaj.org/article/ceaf78c8923c45f0a7ea8d8aea1bad0b
Publikováno v:
PLoS Computational Biology, Vol 16, Iss 11, p e1008424 (2020)
[This corrects the article DOI: 10.1371/journal.pcbi.1007705.].
Externí odkaz:
https://doaj.org/article/366872efe5da4b1eb77da7bd3efa6ebc
Autor:
Laura E Liao, Jonathan Carruthers, Sophie J Smither, CL4 Virology Team, Simon A Weller, Diane Williamson, Thomas R Laws, Isabel García-Dorival, Julian Hiscox, Benjamin P Holder, Catherine A A Beauchemin, Alan S Perelson, Martín López-García, Grant Lythe, John N Barr, Carmen Molina-París
Publikováno v:
PLoS Computational Biology, Vol 16, Iss 11, p e1008375 (2020)
Mathematical modelling has successfully been used to provide quantitative descriptions of many viral infections, but for the Ebola virus, which requires biosafety level 4 facilities for experimentation, modelling can play a crucial role. Ebola virus
Externí odkaz:
https://doaj.org/article/b54f06ac11494b4893a7a1b336957252
Publikováno v:
PLoS Computational Biology, Vol 16, Iss 4, p e1007705 (2020)
Within the human respiratory tract (HRT), virus diffuses through the periciliary fluid (PCF) bathing the epithelium. But virus also undergoes advection: as the mucus layer sitting atop the PCF is pushed along by the ciliated cell's beating cilia, the
Externí odkaz:
https://doaj.org/article/98afc44ee10543f3bacd28f8bda326f8
Publikováno v:
PLoS ONE, Vol 14, Iss 4, p e0214708 (2019)
Many aspects of the respiratory syncytial virus (RSV) are still poorly understood. Yet these knowledge gaps have had and could continue to have adverse, unintended consequences for the efficacy and safety of antivirals and vaccines developed against
Externí odkaz:
https://doaj.org/article/f96cb0c687f34786a81cf10c8642afad
Autor:
Hannah M. Creager, Troy J. Kieran, Hui Zeng, Xiangjie Sun, Joanna A. Pulit-Penaloza, Katie E. Holmes, Anders F. Johnson, Terrence M. Tumpey, Taronna R. Maines, Catherine A. A. Beauchemin, Jessica A. Belser
Publikováno v:
Journal of Virology. 97
Both in vitro and in vivo models are employed for assessing the pandemic potential of novel and emerging influenza A viruses in laboratory settings, but systematic examinations of how well viral titer measurements obtained in vitro align with results
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::787f37691f25773f74a025673aba4c5a
https://doi.org/10.1128/jvi.01536-22
https://doi.org/10.1128/jvi.01536-22