Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Catherine Paradis‑Bleau"'
Autor:
Sean Giacomucci, Laura Alvarez, Christopher D. A. Rodrigues, Felipe Cava, Catherine Paradis-Bleau
Publikováno v:
Microbiology Spectrum, Vol 10, Iss 1 (2022)
ABSTRACT While many mechanisms governing bacterial envelope homeostasis have been identified, others remain poorly understood. To decipher these processes, we previously developed an assay in the Gram-negative model Escherichia coli to identify genes
Externí odkaz:
https://doaj.org/article/deadcdc892874977b4789dc672acddb1
Publikováno v:
PLoS Genetics, Vol 10, Iss 1, p e1004056 (2014)
The cell envelope of Gram-negative bacteria is a formidable barrier that is difficult for antimicrobial drugs to penetrate. Thus, the list of treatments effective against these organisms is small and with the rise of new resistance mechanisms is shri
Externí odkaz:
https://doaj.org/article/ac59dc3744a24142b55b5b8a322e4941
Autor:
Imène, Kouidmi, Laura, Alvarez, Jean François, Collet, Felipe, Cava, Catherine, Paradis-Bleau
Publikováno v:
Journal of bacteriology. 200(19)
Peptidoglycan (PG) is the main structural component of bacterial envelopes. It protects bacterial cells against variations in osmotic pressure and cell lysis. The newly discovered Escherichia coli factor ElyC has been shown to be important for peptid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::91b5166e60f2767534aad5f6e171141d
https://pubmed.ncbi.nlm.nih.gov/30012727
https://pubmed.ncbi.nlm.nih.gov/30012727
Publikováno v:
Journal of bacteriology, Vol. 200, no. 19, p. 1-13 (2018)
Peptidoglycan (PG) is the main structural component of bacterial envelopes. It protects bacterial cells against variations in osmotic pressure and cell lysis. The newly discovered Escherichia coli factor ElyC has been shown to be important for peptid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3df2c659b5b8b7efb068873055d5a1b8
https://hdl.handle.net/2078.1/209412
https://hdl.handle.net/2078.1/209412
We describe the use of the ortho-nitrophenyl-β-galactoside (ONPG) assay developed by Lehrer et al. to which a new mathematical data treatment was applied. In this simplified assay, only one enzymatic assay is needed to provide direct evidence of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::361dde3195ccbaca527e9b446a3c738c
https://europepmc.org/articles/PMC6072009/
https://europepmc.org/articles/PMC6072009/
Publikováno v:
Molecular Microbiology. 94:242-253
Summary With antibiotic resistance mechanisms increasing in diversity and spreading among bacterial pathogens, the development of new classes of antibacterial agents against judiciously chosen targets is a high-priority task. The biochemical pathway
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3ba0b5012292b0d25ad99b701ce4337b
https://doi.org/10.1111/mmi.12758
https://doi.org/10.1111/mmi.12758
Autor:
Roger C. Levesque, Michael A. Quail, Louise Clarke, Julian Parkhill, François Sanschagrin, Catherine Paradis-Bleau, David A. Harris, Kathy Seeger, Robert E. W. Hancock, Fiona S. L. Brinkman, David S. Saunders, Craig Winstanley, Geoff Winsor, Alexandra Bignell, Nicola Lennard, Joanne L. Fothergill, Nicholas R. Thomson, Morgan G. I. Langille, Irena Kukavica-Ibrulj
Publikováno v:
Genome Research. 19:12-23
Pseudomonas aeruginosa isolates have a highly conserved core genome representing up to 90% of the total genomic sequence with additional variable accessory genes, many of which are found in genomic islands or islets. The identification of the Liverpo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e34a8cc65a676011cda354c815d84be9
https://doi.org/10.1101/gr.086082.108
https://doi.org/10.1101/gr.086082.108
Autor:
Hiba Zalloum, Roger C. Levesque, Khaled Younis, Amal G. Al-Bakri, Naji Atallah, Mutasem O. Taha, Catherine Paradis-Bleau
Publikováno v:
Bioorganic & Medicinal Chemistry. 16:1218-1235
The pharmacophoric space of streptococcal MurF was explored using a set of 39 known inhibitors. Subsequently, genetic algorithm and multiple linear regression analysis were employed to select an optimal combination of pharmacophoric models and physic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f2a916e5088706e666ea4e06dca9afb
https://doi.org/10.1016/j.bmc.2007.10.076
https://doi.org/10.1016/j.bmc.2007.10.076
Autor:
Catherine Paradis-Bleau, François Sanschagrin, Normand Voyer, Roger C. Levesque, Mélanie Beaumont
Publikováno v:
Bioorganic & Medicinal Chemistry. 15:1330-1340
As a model system for designing new inhibitors of bacterial cell division, we studied the essential and highly conserved FtsZ GTPase from Pseudomonas aeruginosa. A collection of GTP analogues were prepared using the solid-phase parallel synthesis app
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::228222c68f3c39a25a7eefb08f34412c
https://doi.org/10.1016/j.bmc.2006.11.015
https://doi.org/10.1016/j.bmc.2006.11.015
Autor:
Roger C. Levesque, Catherine Paradis-Bleau, Jérôme Laroche, Michèle Auger, Lise Lemieux, François Sanschagrin, Alain Garnier, Isabelle Cloutier
Publikováno v:
FEMS Microbiology Letters. 266:201-209
The gp144 endolysin gene from the Pseudomonas aeruginosa phage phiKZ was cloned and studies of gp144 expression into Escherichia coli showed host cell lysis. The gp144 protein was purified directly from the culture supernatant and from the bacterial
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e9c961c72a1f2c0ff1d18a069455d3a
https://doi.org/10.1111/j.1574-6968.2006.00523.x
https://doi.org/10.1111/j.1574-6968.2006.00523.x