Zobrazeno 1 - 10
of 60
pro vyhledávání: '"Catherine, Wheeler"'
Autor:
Gregory Ravizzini, Satoshi Matsushima, Yuichi Funase, Eri Nakamura, Masamichi Kajita, Tadashi Matsuura, Hirokazu Satoh, Fumiko Nomura, Mary Johansen, Timothy Madden, Ruth Ann Subach, Takeaki Suzuki, Jason Roszik, Jose Gonzalez, Elmer Santos, Dao Le, Shubham Pant, David S. Hong, Funda Meric-Bernstam, Homer Macapinlac, Holly Liu, Carlos Gonzalez-Lepera, Catherine Wheeler, David Wages, Asa McCoy, Osama Mawlawi, William Erwin, Vivek Subbiah
Purpose:90Y-FF-21101 is an Yttrium-90–conjugated, chimeric mAb that is highly specific for binding to human placental (P)-cadherin, a cell-to-cell adhesion molecule overexpressed and associated with cancer invasion and metastatic dissemination in m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::202aafe290dbe92efdbacbf6b0e01223
https://doi.org/10.1158/1078-0432.c.6529733.v1
https://doi.org/10.1158/1078-0432.c.6529733.v1
Autor:
Gregory Ravizzini, Satoshi Matsushima, Yuichi Funase, Eri Nakamura, Masamichi Kajita, Tadashi Matsuura, Hirokazu Satoh, Fumiko Nomura, Mary Johansen, Timothy Madden, Ruth Ann Subach, Takeaki Suzuki, Jason Roszik, Jose Gonzalez, Elmer Santos, Dao Le, Shubham Pant, David S. Hong, Funda Meric-Bernstam, Homer Macapinlac, Holly Liu, Carlos Gonzalez-Lepera, Catherine Wheeler, David Wages, Asa McCoy, Osama Mawlawi, William Erwin, Vivek Subbiah
Supplemental files for "Phase 1 Study of P-cadherin-Targeted Radioimmunotherapy with 90Y-FF-21101 Monoclonal Antibody in Solid Tumors" Subbiah V et al.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::95071a111f84f2a1837002a47b5e95bd
https://doi.org/10.1158/1078-0432.22477688.v1
https://doi.org/10.1158/1078-0432.22477688.v1
Autor:
Satoshi Matsushima, Tadashi Matsuura, Fumiko Nomura, Catherine Wheeler, Jason Roszik, Ruth Ann Subach, Dao B. Le, Eri Nakamura, Masamichi Kajita, Hirokazu Satoh, David S. Hong, Timothy Madden, Homer A. Macapinlac, Mary Johansen, Osama Mawlawi, Vivek Subbiah, William D. Erwin, Hui Liu, Shubham Pant, Carlos Gonzalez-Lepera, Asa McCoy, Jose Gonzalez, Takeaki Suzuki, David Wages, Elmer B Santos, Gregory Ravizzini, Funda Meric-Bernstam, Yuichi Funase
Publikováno v:
Clinical Cancer Research. 26:5830-5842
Purpose: 90Y-FF-21101 is an Yttrium-90–conjugated, chimeric mAb that is highly specific for binding to human placental (P)-cadherin, a cell-to-cell adhesion molecule overexpressed and associated with cancer invasion and metastatic dissemination in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::843b6371e728c58c1907cab170cd2d6b
https://doi.org/10.1158/1078-0432.ccr-20-0037
https://doi.org/10.1158/1078-0432.ccr-20-0037
Autor:
Vivek, Subbiah, William, Erwin, Osama, Mawlawi, Asa, McCoy, David, Wages, Catherine, Wheeler, Carlos, Gonzalez-Lepera, Holly, Liu, Homer, Macapinlac, Funda, Meric-Bernstam, David S, Hong, Shubham, Pant, Dao, Le, Elmer, Santos, Jose, Gonzalez, Jason, Roszik, Takeaki, Suzuki, Ruth Ann, Subach, Timothy, Madden, Mary, Johansen, Fumiko, Nomura, Hirokazu, Satoh, Tadashi, Matsuura, Masamichi, Kajita, Eri, Nakamura, Yuichi, Funase, Satoshi, Matsushima, Gregory, Ravizzini
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 26(22)
The safety and efficacy ofThe favorable safety profile and initial antitumor activity observed for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::4d4a8b64eec778624d635b453abd7af5
https://pubmed.ncbi.nlm.nih.gov/32816889
https://pubmed.ncbi.nlm.nih.gov/32816889
Autor:
David Tamang, Sagar Lonial, Paul G. Richardson, Robert J Markelewicz, Catherine Wheeler, Jeffrey G. Supko, Robert Z. Orlowski, Noopur Raje, Min Yang, Parameswaran Hari, Dan T. Vogl, Simon S. Jones, Sundar Jagannath
Publikováno v:
Clinical Cancer Research. 23:3307-3315
Purpose: Histone deacetylase (HDAC) inhibition improves the efficacy of proteasome inhibition for multiple myeloma but adds substantial toxicity. Preclinical models suggest that the observed synergy is due to the role of HDAC6 in mediating resistance
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b34b672fe8701743934d21ae2ebc6ecc
https://doi.org/10.1158/1078-0432.ccr-16-2526
https://doi.org/10.1158/1078-0432.ccr-16-2526
Autor:
Timothy Madden, Catherine Wheeler, Kin Yin Cheung, Vivek Subbiah, Satoshi Matsushima, David S. Wages, Debra L. Richardson, Takeaki Suzuki, Ruth Ann Subach, Devalingam Mahalingam, Aparna Kalyan, Taofeek K. Owonikoko, Susanna Varkey Ulahannan, Mary Johansen, Mary F. Mulcahy
Publikováno v:
Journal of Clinical Oncology. 39:78-78
78 Background: Overexpression of the cell-cell adhesion protein P-cadherin has been associated with a more aggressive cancer cell phenotype, cancer stem cell properties, tumor invasion and metastasis. We determined the safety and recommended Phase II
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a1f6e13cbb2c8b145c25c3ad3ed21d2c
https://doi.org/10.1200/jco.2021.39.3_suppl.78
https://doi.org/10.1200/jco.2021.39.3_suppl.78
Autor:
Catherine Wheeler, David Tamang, Jeffrey G. Supko, Edward N. Libby, Andrew Yee, Jesus G. Berdeja, Noopur Raje, Robert J Markelewicz, Peter M. Voorhees, Simon S. Jones, Min Yang, Jill N. Burke, Ellen E. Wallace, William I. Bensinger, Nicole Birrer, Paul G. Richardson
Publikováno v:
The Lancet Oncology. 17:1569-1578
Summary Background Histone deacetylase (HDAC) inhibitors are an important new class of therapeutics for treating multiple myeloma. Ricolinostat (ACY-1215) is the first oral selective HDAC6 inhibitor with reduced class I HDAC activity to be studied cl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9dfa2c7854228ace7aeba59a4eeb7997
https://doi.org/10.1016/s1470-2045(16)30375-8
https://doi.org/10.1016/s1470-2045(16)30375-8
Autor:
Paula Sedivy, Atif Abbas, Takeaki Suzuki, Ruth Ann Subach, Tadaaki Ioroi, Takeshi Matsumoto, Shiraj Sen, Erika Hamilton, Mary Johansen, Timothy Madden, Gerald Steven Falchook, Catherine Wheeler, Suzanne F. Jones, Erkut Borazanci, Gary Maier
Publikováno v:
Journal of Clinical Oncology. 37:TPS3163-TPS3163
TPS3163 Background: FF-10832 (832) is a liposomal formulation of gemcitabine (GEM) that demonstrates a prolonged half-life and preferential uptake in tumor vs normal tissues and marrow in pre-clinical models. Macrophage uptake has been shown in the t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d87d25cebf1a371b7c3a79d0c002f194
https://doi.org/10.1200/jco.2019.37.15_suppl.tps3163
https://doi.org/10.1200/jco.2019.37.15_suppl.tps3163
Autor:
Kazunori Saeki, Gerald Steven Falchook, Vivek Subbiah, Gary Maier, David S. Wages, Bhumika Prajapati, Timothy Madden, Shinji Hagiwara, Catherine Wheeler, Ruth Ann Subach, Mary Johansen, Filip Janku, Takeaki Suzuki, Milind Javle, Cassie Stone, Lindsay Bramwell, Shiraj Sen, Tracey Way, Shubham Pant
Publikováno v:
Journal of Clinical Oncology. 37:3008-3008
3008 Background: FF10502 is a synthetic pyrimidine nucleoside similar to gemcitabine (gem) with a sulfur in the pentose ring. FF10502 is a more potent inhibitor of DNA polymerase Beta than gem with activity in gem resistant patient (pt) derived xenog
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::59d08899f1022cd4c4467b0f4dd76992
https://doi.org/10.1200/jco.2019.37.15_suppl.3008
https://doi.org/10.1200/jco.2019.37.15_suppl.3008
Autor:
Zachary DelProposto, Antoinette J. Wozniak, Scott A. Boerner, Shirish M. Gadgeel, Helen Jones, Jeffrey Evelhoch, Pamela DeLuca, Alan Barge, Catherine Wheeler, Patricia LoRusso
Publikováno v:
Investigational New Drugs. 26:159-167
Background ZD6126 is a novel vascular-targeting agent that disrupts the endothelial tubulin cytoskeleton causing selective occlusion of tumor vasculature and extensive tumor necrosis. This Phase I clinical study was conducted to evaluate the dose and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b0725c4ad9cf852a0a28e3418f816abb
https://doi.org/10.1007/s10637-008-9112-9
https://doi.org/10.1007/s10637-008-9112-9